Protein Alignment Trim9 and Trim63

DIOPT Version :9

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001034137.2
• Gene: Trim63 / 433766
• MGIID: 2447992
• Length: 355
• Species: Mus musculus
• Alignment Length: 457
• Identity: 92/457 - (20%)
• Similarity: 147/457 - (32%)
• Gaps: 153/457 - (33%)

  Fly     1 MEDELRCPTCKQLYANP-VLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHG 64
            :|.:|.||.|.:::..| |:|||.|.||..||.||..     :|.|...|..|:.|.:|..
Mouse    17 LEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQ-----AANPYWTNRGGSVSMSGGR---- 72

  Fly    65 NGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVCC 129
                                                                             
Mouse    73 ----------------------------------------------------------------- 72

  Fly   130 SNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCA 194
                                          ..||.||..|..|..||..|.....:|.|:|
Mouse    73 ------------------------------FRCPSCRHEVIMDRHGVYGLQRNLLVENIID---- 103

  Fly   195 REALRCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRESVCGEHE 259
               :..|.|.:.|                 .::.:||                      :|.|||
Mouse   104 ---IYKQECSSRP-----------------LQKGSHP----------------------MCKEHE 126

  Fly   260 -ETLSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEFIQRL 323
             |.::.|||:|:.|.|.||.....|||.:|..:....:.||||||:.:..|..........|.:|
Mouse   127 DEKINIYCLTCEVPTCSLCKVFGAHQACEVAPLQSIFQGQKTELSNCISMLVAGNDRVQTIISQL 191

  Fly   324 KGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQSNCTGKLQQT 388
            :.......|:..:.:..:..:.:.|...:.:::..||:.|..:::.|:..::........:|:::
Mouse   192 EDSCRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEEKLGFIEALILQYREQLEKS 256

  Fly   389 TGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTLDDAALA-RA 452
            |.|::..|::|.|...|.||.....||..:...........|...........|.|:..|.| ||
Mouse   257 TKLVETAIQSLDEPGGATFLSSAKQLIKSIVEASKGCQLGKTEQGFENMDYFTLDLEHIAEALRA 321

  Fly   453 ID 454
            ||
Mouse   322 ID 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9_like_C-I	2..37	CDD:319490	17/35 (49%)
		zf-B_box	250..291	CDD:306989	17/41 (41%)
		ClassIIa_HDAC_Gln-rich-N	298..420	CDD:330228	26/121 (21%)
		FN3	472..564	CDD:238020
		SPRY_PRY_TRIM67_9	561..735	CDD:293947
Trim63	NP_001034137.2	RING	23..82	CDD:238093	25/162 (15%)
		Interaction with TTN. /evidence=ECO:0000250	74..218		45/189 (24%)
		zf-B_box	120..159	CDD:279037	18/60 (30%)
		iSH2_PI3K_IA_R	166..283	CDD:304922	24/116 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910