DRSC/TRiP Functional Genomics Resources

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Protein Alignment Trim9 and trim63b

DIOPT Version :9

Sequence 1:NP_001188786.1 Gene:Trim9 / 34453 FlyBaseID:FBgn0051721 Length:740 Species:Drosophila melanogaster
Sequence 2:NP_957389.1 Gene:trim63b / 394070 ZFINID:ZDB-GENE-040426-1003 Length:348 Species:Danio rerio


Alignment Length:467 Identity:91/467 - (19%)
Similarity:159/467 - (34%) Gaps:163/467 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MEDELRCPTCKQLYANP-VLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHG 64
            :|.:|.||.|..::..| |:|||.|.||.|||.|:.                             
Zfish    19 LEKQLSCPICLDMFTKPVVILPCQHNLCRGCASDLY----------------------------- 54

  Fly    65 NGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVCC 129
                                                                             
Zfish    55 ----------------------------------------------------------------- 54

  Fly   130 SNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCA 194
             ::..|..::|     ||            ..||.||..|..|..||..|.....:|.|:|    
Zfish    55 -DSRNPYRFSG-----GV------------FRCPTCRFEVVLDRHGVHGLQRNLLVENIID---- 97

  Fly   195 REALRCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRESVCGEHE 259
                              |.:|         ::......|.....:.:||:.:   :|.:|.|||
Zfish    98 ------------------IYKQ---------QQEGGGGGGGSTTESPIKPKSS---KELMCQEHE 132

  Fly   260 -ETLSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEFIQRL 323
             |.::.||::.:.|.|.:|....:|:..:|..:....:|||.|||:.:..|       .....||
Zfish   133 DEKINIYCVTHQTPTCSMCKVFGQHKDCEVSPLASVYQAQKGELSNAIDAL-------VAGNGRL 190

  Fly   324 KGMSDKVTESCMEFE------RLVHAQC-EALIQAIHDRREYLLEAIRMDKDTKIRILKDQQSNC 381
            :.:.:::.|:|...:      :....:| ::|..|:.:|:..|||.|..::|.|:..|:......
Zfish   191 QALLNQMEEACTAVQDNAQRAKQKFGECFDSLYAALEERKNALLERIGKEQDEKVGALRSLARRY 255

  Fly   382 TGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTLDD 446
            ..:||..|.|....::||:::.:|.|||....||::..:...:...| ....|....:...|||.
Zfish   256 GDRLQAATELTDMAVQALEQSGAAEFLQASKNLISQTKDAAKSSLAE-ERPEPGFERMDHFTLDT 319

  Fly   447 AALARAIDNLNF 458
            ..:...:..::|
Zfish   320 EQVETLLSKMDF 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Trim9NP_001188786.1 RING-HC_TRIM9_like_C-I 2..37 CDD:319490 17/35 (49%)
zf-B_box 250..291 CDD:306989 13/41 (32%)
ClassIIa_HDAC_Gln-rich-N 298..420 CDD:330228 33/128 (26%)
FN3 472..564 CDD:238020
SPRY_PRY_TRIM67_9 561..735 CDD:293947
trim63bNP_957389.1 RING 25..76 CDD:238093 23/162 (14%)
zf-B_box 123..165 CDD:279037 13/44 (30%)
iSH2_PI3K_IA_R 172..297 CDD:304922 33/131 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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