Protein Alignment Trim9 and Trim55

DIOPT Version :9

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001074750.1
• Gene: Trim55 / 381485
• MGIID: 3036269
• Length: 545
• Species: Mus musculus
• Alignment Length: 699
• Identity: 136/699 - (19%)
• Similarity: 214/699 - (30%)
• Gaps: 256/699 - (36%)

  Fly     1 MEDELRCPTCKQLYANP-VLLPCFHALCLGCALDI---QTPYSPGSALPGAVNGAGAASAAGHNG 61
            :|.:|.||.|.:::..| |:|||.|.||..||.||   ..||.|
Mouse    20 LEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLP--------------------- 63

  Fly    62 LHGNGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGV 126
                                   ||.
Mouse    64 -----------------------TRG--------------------------------------- 66

  Fly   127 VCCSNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDR 191
                                 |..||..|.   ..||.||..|..|..||..|.....:|.|:|
Mouse    67 ---------------------GTTVASGGR---FRCPSCRHEVVLDRHGVYGLQRNLLVENIID- 106

  Fly   192 FCAREALRCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRESVCG 256
                                 |.:|          |.|.|.:      .|.:|         :|.
Mouse   107 ---------------------IYKQ----------ESTRPEK------KLDQP---------MCE 125

  Fly   257 EH-EETLSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEFI 320
            || ||.::.|||:|:.|.|.||.....|:...|..:....:.||:|||..:..|....
Mouse   126 EHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAVLVGSN------- 183

  Fly   321 QRLKGMSDKVTESCMEFERLVHAQ----CEA---LIQAIHDRREYLLEAIRMDKDTKIRILKDQQ 378
            .|::|:..::.::|...|.....|    ||.   |...:.:|:..:.:||...::.|:..::...
Mouse   184 DRVQGVISQLEDTCKTIEECCRKQKQDLCEKFDHLYGILEERKTEMTQAITRTQEEKLEHVRTLI 248

  Fly   379 SNCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEV-------------- 429
            ...:..|:..:.|::..|:.:.|.:.|.|||....|:.::......:..|.
Mouse   249 RKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLQKIVEASKAFQMEKLEQGYEIMSNFTVN 313

  Fly   430 TNAAPRVSPIVDLTL-----------------DDAALARAIDNLNFIQMRAVKDGDERCPAAPMT 477
            .|...::...:|.:.                 :||......:|     ::....|:|........
Mouse   314 LNREEKIIREIDFSREEEEEEDAGEIDEEGEGEDAVEVEEAEN-----VQIASSGEEESLEKAAE 373

  Fly   478 PTILPSDCSAENNSVTVAWQPPNHSF--------VEGYVLELDDGSGGEFREVYCGKETICTVDG 534
            |:.||::.......:..:...|..|.        .:|.|:.:  ||....:....|.....|.|.
Mouse   374 PSQLPAELQVAPEPLPASSPEPFSSMPPAADVLVTQGEVVPI--GSQQTTQSETSGPSAAETADP 436

  Fly   535 LHFNSMYNARVK--------AFNSAGEGEYSEL----IGLQTAEVAWFTFDPVLSGGAGSGLIFS 587
            |.:.|.|..:.:        ...|.|.|:...|    ..:|:||||....:   ...|.||...|
Mouse   437 LFYPSWYKGQSRKTSSNPPCTHGSEGLGQIGPLGIEDSSVQSAEVAEAATN---EQAAVSGKESS 498

  Fly   588 KNNATVSVEGWE------HRVALGSVGFSRGVHYWEFTIDNYTADTDPA 630
            ...||..: |:|      ...||||.|               .||.:||
Mouse   499 STAATSQI-GFEAPSPQGQSAALGSGG---------------GADPEPA 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9_like_C-I	2..37	CDD:319490	17/38 (45%)
		zf-B_box	250..291	CDD:306989	15/41 (37%)
		ClassIIa_HDAC_Gln-rich-N	298..420	CDD:330228	27/128 (21%)
		FN3	472..564	CDD:238020	19/111 (17%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	22/76 (29%)
Trim55	NP_001074750.1	RING	26..85	CDD:238093	28/165 (17%)
		zf-B_box	120..161	CDD:279037	16/49 (33%)
		iSH2_PI3K_IA_R	168..294	CDD:304922	27/132 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910