Protein Alignment Trim9 and Trim54

DIOPT Version :9

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001013235.1
• Gene: Trim54 / 362708
• RGDID: 1306453
• Length: 364
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 102/542 - (18%)
• Similarity: 180/542 - (33%)
• Gaps: 203/542 - (37%)

  Fly     1 MEDELRCPTCKQLYANP-VLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHG 64
            :|.:|.||.|.::::.| |:|||.|.||..||.|:
  Rat    20 LEKQLICPICLEMFSKPVVILPCQHNLCRKCANDV------------------------------ 54

  Fly    65 NGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVCC 129
                                      ..|::....:.||.:|:|
  Rat    55 --------------------------FQASNPLWQSRGSTTVSS--------------------- 72

  Fly   130 SNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCA 194
                                     |..:  .||.||..|..|..||..|.....:|.|:|
  Rat    73 -------------------------GGRF--RCPSCRHEVVLDRHGVYGLQRNLLVENIID---- 106

  Fly   195 REALRCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRESVCGEHE 259
                                                     :.|....:|..:..::..:|.|||
  Rat   107 -----------------------------------------IYKQESSRPLHSKAEQHLMCEEHE 130

  Fly   260 -ETLSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEFIQRL 323
             |.::.|||||:.|.|.||.....|:..:|..:....|.||:|||..:..|..........|.::
  Rat   131 DEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQM 195

  Fly   324 KGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQSNCTGKLQQT 388
            :.:...:.::....::|::.:.|.|...:.:|:..||:|:...::.|::.::.........|:.:
  Rat   196 EEVCQTIEDNSRRQKQLLNQKFETLCAVLEERKGELLQALARVQEEKLQRVRSLIRQYGDHLEAS 260

  Fly   389 TGLIQFCIEALKETDSAAFLQVGSMLINRV---TNTDMTWHQEV-TNAAPRVSPIVDLTLDDAAL 449
            :.|::..|::::|...|.:||....|||:|   :..::....|. ..:..:.|.||:..   |.:
  Rat   261 SKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFSVIVEHV---AEM 322

  Fly   450 ARAIDNLNFIQMRAVKDGDERCPAAPMTPTILPSDCSAENNSVTVAWQPPNHSFVEGYVLELDDG 514
            .|.||      .:....|||                  |::.||               |:.::|
  Rat   323 LRTID------FQPGASGDE------------------EDDEVT---------------LDGEEG 348

  Fly   515 SGGEFREVYCGKETICTVDGLH 536
            :.|...|...|.|      |||
  Rat   349 NTGLEEERLDGPE------GLH 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9_like_C-I	2..37	CDD:319490	16/35 (46%)
		zf-B_box	250..291	CDD:306989	16/41 (39%)
		ClassIIa_HDAC_Gln-rich-N	298..420	CDD:330228	26/124 (21%)
		FN3	472..564	CDD:238020	12/65 (18%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947
Trim54	NP_001013235.1	RING	26..85	CDD:238093	24/162 (15%)
		zf-B_box	125..163	CDD:279037	16/37 (43%)
		Mediates microtubule-binding and homooligomerization. /evidence=ECO:0000250	168..211		8/42 (19%)
		iSH2_PI3K_IA_R	170..>273	CDD:304922	18/102 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..364		13/74 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910