Protein Alignment Trim9 and trim69

DIOPT Version :10

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_073769570.1
• Gene: trim69 / 101883816
• ZFINID: ZDB-GENE-030131-857
• Length: 562
• Species: Danio rerio
• Alignment Length: 730
• Identity: 134/730 - (18%)
• Similarity: 213/730 - (29%)
• Gaps: 305/730 - (41%)

  Fly     4 ELRCPTCKQLYANPVLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHGNGGG 68
            :|.|..|..|:..||.|||.|..|..|.    |.|.
Zfish    87 DLTCSICLDLFKQPVSLPCDHTFCEACI----TSYW----------------------------- 118

  Fly    69 AGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVCCSNTS 133
                        :||..:                                          |.
Zfish   119 ------------SGPRVK------------------------------------------CQ--- 126

  Fly   134 RPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCAREAL 198
                 ||:|                  :||.||| ||.   |....|. |.:..||:.:|.
Zfish   127 -----AGSG------------------SCPQCRK-VFH---GKSYRPN-RIVANIVESYCQ---- 159

  Fly   199 RCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRESVCGEHEETLS 263
              .|.|:..::.:                ::.||  |.|               .:|..|.|.|.
Zfish   160 --GMEESGVRLGA----------------VSEPA--PTA---------------PLCMRHREELK 189

  Fly   264 QYCLSCKAPACGLCIGELRHQAH------DVQ-----SINVTCKAQKTELSHNLQQLSEKARSTT 317
            .||...:...|.:|.....|:||      |.|     |:..:..|.:.||:..|    |..|.|.
Zfish   190 LYCEEDQELVCLVCGISQDHRAHTLVCVQDAQKRYRASLTTSANALQKELNTAL----ECERETE 250

  Fly   318 EFIQRLKGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQSNCT 382
            |.:::||       :...:.::.:.||...|.|.::...:.|          ::::..:::.
Zfish   251 EEVKKLK-------DHTADLKQRIEAQFSELHQFLYQEEKLL----------QVKLKTEERR--- 295

  Fly   383 GKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTLDDA 447
                          |.::..:..|.|.|....:.|..|       ::.:......|
Zfish   296 --------------ELIRLDEHKALLSVEISRLRRAVN-------DIEDKLSEQDP--------- 330

  Fly   448 ALARAIDNLNFIQMRAVKDGDERCPAAPMTPTILPSDCSAENNSVTVAWQPPNHSFVEGYVLELD 512
                      :..:|::|...:|.|.....||:.|.                  |..||..
Zfish   331 ----------YTLLRSIKGLLQRQPPKFERPTLTPP------------------SLCEGRF---- 363

  Fly   513 DGSGG-EFREVYCGKETICTVDGLHFNSMYNARVKAFNSAGEGEYSELIGLQTAEVAWFTFDPVL 576
              :|. ::|.....|.:|..|..          ...|||.....:..|....|. |.:.||:..:
Zfish   364 --AGPLQYRVWKSLKGSIYPVPS----------AITFNSKTANPWLSLTSSLTC-VRYQTFNSSV 415

  Fly   577 SGGAGSGLIFSKNNATVSVEGWEHRVALGSVGFSRGVHYWEFTIDNYTADTDPAFGVARIDVARN 641
            ....      .:.||.:|:        :|..||::|.||||..:.:.|..|   .||||..|.|.
Zfish   416 QDNP------QRFNAALSL--------MGGQGFTKGRHYWEVEVYSSTVWT---VGVARESVTRK 463

  Fly   642 KMLGKDEKSFAMYIDRQRSWFQHNSIHERRVEGGITTGST----------IGVLLDLERHTLSFL 696
            .::..        :.....|....|...:.:.|  |:..|          |||.||.:|..:||.
Zfish   464 GVINT--------MPANGFWTLSLSYGVQYMAG--TSPPTLLSLEEPLARIGVYLDYKRGLVSFY 518

  Fly   697 VNEMPQGSVAFRDLY 711
            ..|.......|||.:
Zfish   519 NAESMTHLYTFRDTF 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9-like_C-I	2..>35	CDD:438238	12/30 (40%)
		Bbox1_TRIM9-like_C-I	199..244	CDD:380861	6/44 (14%)
		Bbox2_TRIM9-like	255..291	CDD:380822	13/46 (28%)
		CC_brat-like	298..420	CDD:475168	19/121 (16%)
		FN3	472..564	CDD:238020	16/92 (17%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	40/161 (25%)
trim69	XP_073769570.1	None