Protein Alignment Trim9 and trim21

DIOPT Version :10

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_002942762.2
• Gene: trim21 / 100490741
• XenbaseID: XB-GENE-17329851
• Length: 525
• Species: Xenopus tropicalis
• Alignment Length: 744
• Identity: 141/744 - (18%)
• Similarity: 217/744 - (29%)
• Gaps: 316/744 - (42%)

  Fly     1 MEDELRCPTCKQLYANPVLLPCFHALCLGC---ALDIQTPYSPGSALPGAVNGAGAASAAGHNGL 62
            :.:||.|..|..:|::|::|||.|..|.||   .||.|
 Frog     7 LREELNCSVCLSIYSDPIMLPCGHNFCQGCIGRVLDTQ--------------------------- 44

  Fly    63 HGNGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVV 127
                                                                             
 Frog    45 ----------------------------------------------------------------- 44

  Fly   128 CCSNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRF 192
                       .|||:                .|||.||..........||    |.:..|.:||
 Frog    45 -----------EGTGV----------------YTCPECRAEYPERPALQRN----RTLGNIAERF 78

  Fly   193 -CAR-----EALRCQMCETDPKVASLICEQCEIRYCDACRELTH-PARGPLAKHTLVKPRGAAQQ 250
             ||:     ..:.|..|...|..|:..|..||...|:     :| ......|:|.||:|..|.::
 Frog    79 LCAQPGPGGTGIYCTYCIHSPVAAAKSCLLCEASLCE-----SHVRVHSRSAEHVLVEPTTAPEK 138

  Fly   251 RESVCGEHEETLSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARS 315
            |:  |..|.|.|..||....|..|..|....:|:.|.|:.::.....:|.:|...|..|......
 Frog   139 RK--CSAHGEPLKYYCYEDSACICASCCLGGQHKRHRVELLSEASDRKKEQLRKVLLNLPLMIEE 201

  Fly   316 TTEFIQRLKGMSDKVTESCM-EFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKD--- 376
            |....|:|:....::.|... |.:|:|     ||...|.:|    |||:..      |:|.:
 Frog   202 TERGAQKLQERRVQMQEQAAGEMDRVV-----ALFADIRER----LEALER------RVLSEIAR 251

  Fly   377 QQSNCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVD 441
            |:...|.:..:   ||. .:|..||..|...||.                :|:.|.|   .|:..
 Frog   252 QEEELTARASE---LIH-QLEIKKEELSRKILQT----------------EELCNMA---DPLAV 293

  Fly   442 LTLDDAALARAIDNLNFIQMRAVKDGDERCPAAPMTPTILPSDCSAENNSVTVAWQPPNHSFVEG 506
            |...|                                       |.|::.|..:.:|...|.
 Frog   294 LQTHD---------------------------------------SDEHDGVRESQEPRGPSL--- 316

  Fly   507 YVLELDDGSGGEFRE------VYCGKETICTVDGLHFNSMYNARVKAFNSAGEGEYSELIGLQTA 565
                      |:..|      ::.|.|:|...            .|.....|:|....|:.:.||
 Frog   317 ----------GDLNEDLISETLHAGLESIVMA------------AKGLGVYGKGAAHVLLDINTA 359

  Fly   566 EVAWFTFDPVLSGGAGSGLIFSKNNATVSVE---------------------GWEHRVALGSVGF 609
                                  .||..||.:                     |::   .|.:..|
 Frog   360 ----------------------SNNVAVSEDRKTASWTSTNQLRPQTPPRFIGYQ---ILSTNSF 399

  Fly   610 SRGVHYWEFTIDNYTADTDPAFGVARIDVAR--NKM-LGKDEKSFAMYIDRQRSWFQHNSIHERR 671
            :.|.|:|:..:   :.......|||...:.|  |:. :|.:.||:.:       |..:|:...|.
 Frog   400 TSGRHFWDMEV---SESGSWRVGVAYPSIGRKGNQFWIGNNIKSWCL-------WRWNNAYSVRH 454

  Fly   672 VEGG-----ITTGSTIGVLLDLERHTLSF 695
            .:.|     :.:.:.|.|.||.....|||
 Frog   455 DQHGTDLPLLPSCTRIRVSLDYGAGRLSF 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9-like_C-I	2..>35	CDD:438238	15/35 (43%)
		Bbox1_TRIM9-like_C-I	199..244	CDD:380861	13/45 (29%)
		Bbox2_TRIM9-like	255..291	CDD:380822	12/35 (34%)
		CC_brat-like	298..420	CDD:475168	30/125 (24%)
		FN3	472..564	CDD:238020	14/97 (14%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	31/164 (19%)
trim21	XP_002942762.2	RING-HC_TRIM25_C-IV	6..77	CDD:438259	28/192 (15%)
		Bbox_SF	92..132	CDD:469587	13/44 (30%)
		Bbox2_TRIM16-like	139..185	CDD:380827	13/47 (28%)
		CC_brat-like	184..295	CDD:475168	34/148 (23%)
		SPRY_PRY_C-I_2	352..514	CDD:293949	32/167 (19%)