Protein Alignment Trim9 and trim46b

DIOPT Version :10

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_009292294.1
• Gene: trim46b / 100034631
• ZFINID: ZDB-GENE-060503-466
• Length: 780
• Species: Danio rerio
• Alignment Length: 832
• Identity: 195/832 - (23%)
• Similarity: 294/832 - (35%)
• Gaps: 245/832 - (29%)

  Fly     1 MEDELRCPTCKQLYANPVLLPCFHALCLGCALD--IQTPYSPGSALPGAVNGAGAASAAGHNGLH 63
            ||.||:||.||.:...|::|||.|::||.||.:  ||:.| |...||...|
Zfish    20 MEQELQCPVCKDIVKQPIVLPCLHSVCLMCASEVLIQSGY-PQPELPPEPN-------------- 69

  Fly    64 GNGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVC 128
                       :|.:.||....|                  .:.....:||:|.
Zfish    70 -----------SPASTPNMRSPR------------------QMRRPMPKSDRVD----------- 94

  Fly   129 CSNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGG----VRNLPTYRAMEAIV 189
                  .:..:|:|..||......|| ......|..|.:.|...:.|    :|||    |:|.||
Zfish    95 ------RLLRSGSGTYPGRRRKDGPP-PLMLFPCAPCGRDVELGERGLAECMRNL----ALERIV 148

  Fly   190 DRF-----CAREALRCQMCETDPKV-ASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAA 248
            :|:     ....|:.||.|:....: |:..|..|...:|:.|.:|.||...|.|:|..|:|....
Zfish   149 ERYRHTVSLGSVAVMCQFCKPPQALEATKGCADCRASFCNECFKLYHPWGTPRAQHEHVQPTLNF 213

  Fly   249 QQRESVCGEH-EETLSQYCLSCKAPACGLCIGELR--HQAHDVQSINVTCKAQKTELSHNLQQ-L 309
            :.:...|.|| :|.|..||.||:...|.||  :||  |..|.:..:....:..|.:::..|.. |
Zfish   214 RPKVLTCPEHDQERLQYYCKSCQMLLCSLC--KLRRVHAGHKIAPVTQAYQTLKDKITKELNYIL 276

  Fly   310 SEKARSTTEFIQRLKGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRIL 374
            |.:....|:..|....::.....|....|:|.|...| ::..:.:|:..|.:|:...:..:...|
Zfish   277 SNQDMVLTQITQLESAVTQTEVNSVSAKEQLSHCVKE-IMALLTERQTMLAQALEGSRQRRADAL 340

  Fly   375 KDQQSNCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPI 439
            ..|.:.....|:. .||:.|..|.|||.|.::|:....:..||:..:..:......:|.|...
Zfish   341 SSQVAEKRSLLEH-AGLMAFTQELLKENDPSSFVHAARITHNRLAQSIESMQHFALSADPSFR-- 402

  Fly   440 VDLTLDDAALARAIDNLNFIQMRAVKDGDERCPAAPMTPTI----------------LPSDCSAE 488
             ...||.:...:.:.:|||||             ||..|.|                ||.|.
Zfish   403 -HFQLDISRELKLLTDLNFIQ-------------APFAPVIDTQRTLAYDQLFLCWRLPQDS--- 450

  Fly   489 NNSVTVAWQPPNHSFVE----GYVLELDDGSGGEFR-------------EVYCGKETICTVDGLH 536
                |.||    |..||    |.|  ...|:.|..|             |...|  |...:|.|.
Zfish   451 ----TPAW----HFSVEFRRRGVV--PGGGARGGIRGGLAAARWGWQRLEEVTG--TCAVIDRLE 503

  Fly   537 FNSMYNARVKAFNSAGEGEYSELIGLQTAEVAWFTFDPVLS-------GGAGSGLIFSKNNATV- 593
            .:|:|..||:..|.||.|||||.:.|.|...      |||:       |.....|:.||.....
Zfish   504 MDSVYVLRVRGCNKAGFGEYSEEVYLHTPPA------PVLNFYLDSRWGLHADRLVVSKEQRCAR 562

  Fly   594 SVEGWE------------HRVA---LGSVGFSRGVHYWEFTIDNYTADTDPAFGVARIDVARNKM 643
            ||.|..            |..|   :|.|..::|.|||..::       :|...:.::.|.....
Zfish   563 SVPGLSLLQAADRALTSCHLTADLLVGDVAITQGRHYWACSV-------EPGSYLVKVGVGLESK 620

  Fly   644 L-----------------------GKDEKS-----FAMYIDRQRSWFQHNSIHERRV-----EGG 675
            |                       |.::.|     ||.........:..:|::....     |.|
Zfish   621 LQEWFHLPQDMASPRFDPDSGHDSGAEDSSDSPPPFAFLTMGMGKIYLPSSVNSHHCNANYRESG 685

  Fly   676 ITTGS--------------TIGVLLDLERHTLSFLVNEMPQGSVAFRDLYGV 713
            .|.|:              .:||.||.|:            |.|.|.|.:.:
Zfish   686 FTNGNGPSSPTGVTYPLPPRLGVCLDFEK------------GRVTFYDAHSL 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9-like_C-I	2..>35	CDD:438238	16/34 (47%)
		Bbox1_TRIM9-like_C-I	199..244	CDD:380861	15/45 (33%)
		Bbox2_TRIM9-like	255..291	CDD:380822	16/38 (42%)
		CC_brat-like	298..420	CDD:475168	28/122 (23%)
		FN3	472..564	CDD:238020	36/124 (29%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	41/223 (18%)
trim46b	XP_009292294.1	RING-HC_TRIM46_C-I	20..55	CDD:438415	17/34 (50%)
		Bbox1_TRIM46_C-I	161..213	CDD:380907	17/51 (33%)
		Bbox_SF	216..262	CDD:469587	16/47 (34%)
		CC_brat-like	259..378	CDD:475168	26/120 (22%)
		COS	367..416	CDD:465805	8/51 (16%)
		FN3	438..531	CDD:238020	32/107 (30%)
		SPRY_PRY_TRIM46	538..756	CDD:293952	36/207 (17%)