DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18302 and Lipm

DIOPT Version :9

Sequence 1:	NP_609420.1	Gene:	CG18302 / 34452	FlyBaseID:	FBgn0032266	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_076392.1	Gene:	Lipm / 78753	MGIID:	1926003	Length:	422	Species:	Mus musculus

Alignment Length:	401	Identity:	128/401 - (31%)
Similarity:	217/401 - (54%)	Gaps:	19/401 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ILISLFIFCDTASGDLIKVDKTILEDANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIP---- 73
            ||::..:..:..||.|  ..|....:|.:...::||..|||:|.:::..:||::|:.:|||
Mouse    21 ILVAYLLQRNVNSGHL--PTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQT 83

  Fly    74 ---KPGGQP-VLLVHGLLDSSVAYVILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQ 134
               |.|.:| |||.||||..:..::...|..||||:|:|.|:|||:.|:|||.:|||||.....|
Mouse    84 RLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQ 148

  Fly   135 PQFWDFSFHELGVYDLPAAIDYVLARSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQAL 199
            .:||.||:.|:..:||||.|:::|.::.. ::::|||:|||||..|:..|.......|||:..||
Mouse   149 DEFWAFSYDEMARFDLPAVINFILQKTGQ-KKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFAL 212

  Fly   200 APVVFWDYIDSPIILTFVKY-LRPLVFIARSFGIYEFPPENEVWRSLIHKIC-SFVFQNTCTYFL 262
            ||:....|..||    ..|: |.|.:.|...||..||..:...:|.|...:| ..:....|:..:
Mouse   213 APIATVKYARSP----GTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNII 273

  Fly   263 MEAMGVDYAQFNSSLLPLFTGHASSGSSVKSLEHYGQQIHSGGFFKYNYYSTWENRRNHGVDTPP 327
            :...|.:....|.|...::..|..:|:||:::.|:.|.::||....:::.|..:|:......||.
Mouse   274 LLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQPTPI 338

  Fly   328 QYKLTNVDCKVALYYSRNDRLTSDKDVVRLRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLND 392
            :||:.::....|::....|.|::..||..|...:.|::.....|:  :.|::||||.|....:.:
Mouse   339 RYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPE--WAHVDFIWGLDAPQRVYN 401

  Fly   393 RMIELMRKVDN 403
            .:|.||::..|
Mouse   402 EIIHLMKQEPN 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18302	NP_609420.1	PLN02872	13..399	CDD:215470	126/395 (32%)
		Abhydro_lipase	43..97	CDD:282003	22/61 (36%)
		Abhydrolase_5	79..>208	CDD:289465	57/129 (44%)
Lipm	NP_076392.1	PLN02872	50..408	CDD:215470	119/364 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831835
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.810