DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18302 and Lipf

DIOPT Version :9

Sequence 1:	NP_609420.1	Gene:	CG18302 / 34452	FlyBaseID:	FBgn0032266	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_080610.1	Gene:	Lipf / 67717	MGIID:	1914967	Length:	395	Species:	Mus musculus

Alignment Length:	373	Identity:	133/373 - (35%)
Similarity:	202/373 - (54%)	Gaps:	21/373 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 DANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIP-------KPGGQPV-LLVHGLLDSSVAYV 94
            :||:....:|..:|||:|.:::..:||::|..:|||       ..|.:|| .|.|||:.|:..::
Mouse    29 EANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKKNSENIGKRPVAYLQHGLIASATNWI 93

  Fly    95 ILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHELGVYDLPAAIDYVLA 159
            ...|..||.|:|:|.||||||.|:|||.:|||:..|.....:||.|||.|:..|||||.||:::.
Mouse    94 TNLPNNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATIDFIVQ 158

  Fly   160 RSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQALAPVVFWDYIDSPI--ILTFVKYLRP 222
            ::.. |:|||||||||||..|:..|...|..||||...|||||....|.:||.  |....|:|..
Mouse   159 KTGQ-EKIHYVGHSQGTTIGFIAFSTNPALAKKIKRFYALAPVATVKYTESPFKKISLIPKFLLK 222

  Fly   223 LVFIARSFGIYEFPPENEVWRSLIHKICS-FVFQNTCTYFLMEAMGVDYAQFNSSLLPLFTGHAS 286
            ::     ||...|.|.|.:.:.|..::|| .:....|:..|....|.|....|.|...::.||..
Mouse   223 VI-----FGNKMFMPHNYLDQFLGTEVCSRELLDLLCSNALFIFCGFDKKNLNVSRFDVYLGHNP 282

  Fly   287 SGSSVKSLEHYGQQIHSGGFFKYNYYSTWENRRNHGVDTPPQYKLTNVDCKVALYYSRNDRLTSD 351
            :|:|.:.|.|:.|...||....||:.|..:|..::...|||.|.::.:...:|::...:|.|...
Mouse   283 AGTSTQDLFHWAQLAKSGKLQAYNWGSPLQNMLHYNQKTPPYYDVSAMTVPIAVWNGGHDILADP 347

  Fly   352 KDVVRLRDILPNVVL-DYMFPDPLYNHINFIWGNDVKTVLNDRMIELM 398
            :||..|...|||::. ..:.|   |||::|||..|....:.:.::.:|
Mouse   348 QDVAMLLPKLPNLLYHKEILP---YNHLDFIWAMDAPQEVYNEIVTMM 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18302	NP_609420.1	PLN02872	13..399	CDD:215470	133/373 (36%)
		Abhydro_lipase	43..97	CDD:282003	19/61 (31%)
		Abhydrolase_5	79..>208	CDD:289465	64/129 (50%)
Lipf	NP_080610.1	PLN02872	35..389	CDD:215470	130/362 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831805
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.810