DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18302 and CG31089

DIOPT Version :9

Sequence 1:	NP_609420.1	Gene:	CG18302 / 34452	FlyBaseID:	FBgn0032266	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_733128.1	Gene:	CG31089 / 43135	FlyBaseID:	FBgn0051089	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	129/381 - (33%)
Similarity:	197/381 - (51%)	Gaps:	26/381 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 ANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIP-----------KPGGQPVLLVHGLLDSSVA 92
            :.:.|.|....:|||:|.|.|..:||::|...|||           :|   .|||.|||...|.|
  Fly    44 SKITTADRTAAHGYPSEHHHIVTEDGYILGVFRIPYSHKLQNQNEKRP---IVLLQHGLTSCSDA 105

  Fly    93 YVILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHELGVYDLPAAIDYV 157
            :::.||...|.:||:|.|:|||:.|.||..|||.|.......|.||.||:||:|:||:.|.|||.
  Fly   106 WILQGPNDGLPYLLADAGFDVWMGNARGTSYSRNHTTLSPDHPNFWKFSWHEIGIYDITAIIDYA 170

  Fly   158 LA--RSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQALAPVVFWDYIDSPIILTFVKYL 220
            |:  ..:..:.|||||||||||.||.:.|....|..|||.....|||.....:.|.::.:...||
  Fly   171 LSTENGQGQDAIHYVGHSQGTTVFFALMSWIPEYNDKIKTAHMFAPVAIMKNLSSGLVRSVGPYL 235

  Fly   221 RPLVFIARSFGIYEFPPENEVWRSLIHKIC--SFVFQNTCTYFLMEAMGVDYA--QFNSSLLPLF 281
            ......:..||..||.|.||...::...||  .|:.:..|.    .||...||  :.|.:.:|..
  Fly   236 GHRNTYSVLFGSQEFLPHNEFLMAIFFNICQPDFMLRPVCE----SAMEKLYAGGRVNMTAMPEG 296

  Fly   282 TGHASSGSSVKSLEHYGQQIHSGGFFKYNYYSTWENRRNHGVDTPPQYKLTNVDCKVALYYSRND 346
            .....:|.|...:.||.|:..| |:|:...:.|.:|...:|...||:|.:..::..|.::|:.:|
  Fly   297 MATHPAGCSTDQMLHYLQEQQS-GYFRLFDHGTKKNLEVYGTQEPPEYPVELINSLVHMWYADSD 360

  Fly   347 RLTSDKDVVRLRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLNDRMIELMRKVD 402
            .|.:.:||.::.:.|||.|:..| .|..:||.:|....:|:..:|:.:|::|.:.:
  Fly   361 NLAAVEDVEQIAERLPNKVMHRM-ADTEWNHGDFALNWEVRKYINEPVIDIMMEYE 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18302	NP_609420.1	PLN02872	13..399	CDD:215470	128/376 (34%)
		Abhydro_lipase	43..97	CDD:282003	23/64 (36%)
		Abhydrolase_5	79..>208	CDD:289465	61/130 (47%)
CG31089	NP_733128.1	Abhydro_lipase	48..110	CDD:282003	23/64 (36%)
CG31089	NP_733128.1	Abhydrolase	<86..>237	CDD:304388	65/153 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439512
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	9	8.990