DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18302 and Lipo3

DIOPT Version :9

Sequence 1:	NP_609420.1	Gene:	CG18302 / 34452	FlyBaseID:	FBgn0032266	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001013792.2	Gene:	Lipo3 / 381236	MGIID:	2147592	Length:	399	Species:	Mus musculus

Alignment Length:	379	Identity:	121/379 - (31%)
Similarity:	203/379 - (53%)	Gaps:	19/379 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 DANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIP-----KPGGQPVLLV---HGLLDSSVAYV 94
            :|::...::||.:.||:|.:::...||::|..:|||     .....|.::|   ||||.:..|:|
Mouse    28 EAHMNVSEIIKHWDYPSEEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCQHGLLATPGAWV 92

  Fly    95 ILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHELGVYDLPAAIDYVLA 159
            ...|..||.|:|:|.|||||:.::||:.:::||...:....:||||||.::..|||||.|:::|.
Mouse    93 SNPPVNSLAFILADAGYDVWMGSSRGSTWAKKHVALNPDSKEFWDFSFDQMIKYDLPATINFILD 157

  Fly   160 RSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQALAPVVFWDYIDSPIILTFVKYLRPLV 224
            ::.. :||:|:||||||.......:......:||||...|||:  :....|..|.....||.|..
Mouse   158 KTGQ-KQIYYIGHSQGTLLAIGAFATNQTLAEKIKLNILLAPI--YSVQHSKGISHLASYLTPTT 219

  Fly   225 FIARSFGIYEFPPENEVWRSLIHKICSFVFQNTCTYFLMEAMGVDYA--QFNSSLLPLFTGHASS 287
             |...||..||.| ..|:..:...:|:..|.......:|.:|| .|:  |.|.|.|.::.....:
Mouse   220 -IKLLFGEKEFFP-TVVFSEVGACVCNINFFTAICAAIMGSMG-GYSPDQLNKSRLDVYVKLNLA 281

  Fly   288 GSSVKSLEHYGQQIHSGGFFKYNYYSTWENRRNHGVDTPPQYKLTNVDCKVALYYSRNDRLTSDK 352
            |:|||.|.||.|...||....|::.|...|.:::...|||.|.:.::....|::....|.|:..:
Mouse   282 GTSVKVLIHYNQVGRSGILQAYDWGSPSLNMQHYNQTTPPVYNVEDMKVPTAMFTGLKDFLSDPE 346

  Fly   353 DVVRLRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLNDRMIELMRKVDNGEV 406
            ||..|:..:.|  |.|:...|.::|.:||.|.:.:..:::.::.::||.: |:|
Mouse   347 DVEILKPKIHN--LTYLKTIPDFSHFDFILGLNARKEVSEEILTILRKYE-GDV 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18302	NP_609420.1	PLN02872	13..399	CDD:215470	117/370 (32%)
		Abhydro_lipase	43..97	CDD:282003	19/61 (31%)
		Abhydrolase_5	79..>208	CDD:289465	52/131 (40%)
Lipo3	NP_001013792.2	PLN02872	34..391	CDD:215470	116/364 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.810