DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18302 and CG31871

DIOPT Version :9

Sequence 1:	NP_609420.1	Gene:	CG18302 / 34452	FlyBaseID:	FBgn0032266	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_723607.1	Gene:	CG31871 / 34463	FlyBaseID:	FBgn0051871	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	174/382 - (45%)
Similarity:	248/382 - (64%)	Gaps:	10/382 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GDLIKVDKTILEDANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIPKPGGQPVLLVHGLLDSS 90
            |..:|.|  :||||:||||.||:|||||:|||.:..|||::|..|||||.|.|||||:||:||:|
  Fly    64 GRNLKSD--VLEDASLITPKLIRKYGYPSETHTVVTKDGYILEMHRIPKKGAQPVLLMHGILDTS 126

  Fly    91 VAYVILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHELGVYDLPAAID 155
            ..:|::||:..||::|||:|||||:.|:||||||:.|...:....:||||:|||:|.|||||.||
  Fly   127 ATWVLMGPKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDYQEFWDFTFHEMGKYDLPANID 191

  Fly   156 YVLARSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQALAPVVFWDYIDSPIILTFVKYL 220
            |:|::: .:||:||:||||||..|:|:.||:.||.:||..|.||||:.:...:.||:..|.|.:|
  Fly   192 YILSKT-GYEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSMHALAPIAYIHDMKSPLFRTLVLFL 255

  Fly   221 RPLVFIARSFGIYEFPPENEVWRSLIHKIC--SFVFQNTCTYFLMEAMGVDYAQFNSSLLPLFTG 283
            ..|....|...|.||.|..:........:|  :.:.|:.|:..|....|.:..|.|.::||:...
  Fly   256 DFLTAATRMLRITEFMPNTKFLVDHSQVVCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLPVMLS 320

  Fly   284 HASSGSSVKSLEHYGQQIHSGGFFKYN--YYSTWENRRNHGVDTPPQYKLTNVDCKVALYYSRND 346
            |..||:|:|.|||:||.:.||.|.|::  |.   .|:..:...|||.|.|:.|...||||||.||
  Fly   321 HTPSGASIKQLEHFGQLMKSGHFRKFDRGYL---RNQLEYNRMTPPDYDLSRVKVPVALYYSVND 382

  Fly   347 RLTSDKDVVRLRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLNDRMIELMRKVDN 403
            .|.|...|.||...||||:..|:.|...:||::|:|..|||.::.:|::..:|:|:|
  Fly   383 LLVSTTGVDRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVRNVRRVEN 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18302	NP_609420.1	PLN02872	13..399	CDD:215470	171/376 (45%)
		Abhydro_lipase	43..97	CDD:282003	33/53 (62%)
		Abhydrolase_5	79..>208	CDD:289465	70/128 (55%)
CG31871	NP_723607.1	Abhydro_lipase	79..133	CDD:282003	33/53 (62%)
		MhpC	93..436	CDD:223669	151/346 (44%)
		Abhydrolase_5	115..281	CDD:289465	81/166 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438244
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	11	10.800