DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18302 and CG2772

DIOPT Version :9

Sequence 1:	NP_609420.1	Gene:	CG18302 / 34452	FlyBaseID:	FBgn0032266	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	140/393 - (35%)
Similarity:	202/393 - (51%)	Gaps:	48/393 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 IKKYGYPAETHKIQAKDGFVLTAHRIP-------------KPGGQPVLLV-HGLLDSSVAYVILG 97
            |.::|||||:|.::..||:||...|||             ....:||:|: |||...|..:::.|
  Fly    39 IAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNG 103

  Fly    98 PERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHELGVYDLPAAIDYVLARSK 162
            ||.:|.:..:|.||||||.|.|||.|||.:.|.:...|.||.||:||:|..||||.|||:||.:.
  Fly   104 PEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILAETG 168

  Fly   163 DFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQALAPVVFWDYIDSPIILTFVKYLRPLVFIA 227
            . :.:||||||||.||||||||.|..|..|||....|||.|:.......:|::    ..||
  Fly   169 Q-QSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPPVYMGNSTEGLIVS----TAPL---- 224

  Fly   228 RSFGIYEFP----------PENEVWRSLIHKICSF--VFQNTCTYFLMEAMGVDYAQFNSSLLPL 280
              ||.:...          |:|...:.::...||.  :..:.|....:...|.:....|.:|||.
  Fly   225 --FGHHGIGSTLLENQVLLPQNAFIQRVLDTTCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQ 287

  Fly   281 FTGHASSGSSVKSLEHYGQQIHSGGFFKYNYYSTWENRRN---HGVDTPPQYKLTNVDCKVALYY 342
            ......:|.|.....||.|...|..|..|:    |.::||   :||..||.|.||.:..::.|||
  Fly   288 IAETHPAGVSSNQAIHYIQSYASNDFRLYD----WGSKRNLEYYGVSEPPAYDLTKITSELYLYY 348

  Fly   343 SRNDRLTSDKDVVRLRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLNDRMIELMRKVD----N 403
            ...|...:.:|:.||.|:|||:.|.:..||..:.|::||:..:||.|:||.:::..:..|    |
  Fly   349 GLADGSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLDYSKAYDARETN 413

  Fly   404 GEV 406
            .|:
  Fly   414 NEI 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18302	NP_609420.1	PLN02872	13..399	CDD:215470	137/380 (36%)
		Abhydro_lipase	43..97	CDD:282003	21/63 (33%)
		Abhydrolase_5	79..>208	CDD:289465	68/129 (53%)
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	132/368 (36%)
		Abhydro_lipase	36..103	CDD:282003	21/63 (33%)
		Abhydrolase	113..>196	CDD:304388	50/83 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439492
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	11	10.800