DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18302 and Lipo1

DIOPT Version :9

Sequence 1:	NP_609420.1	Gene:	CG18302 / 34452	FlyBaseID:	FBgn0032266	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_006231364.1	Gene:	Lipo1 / 294097	RGDID:	1565682	Length:	397	Species:	Rattus norvegicus

Alignment Length:	401	Identity:	121/401 - (30%)
Similarity:	203/401 - (50%)	Gaps:	26/401 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LISLF--IFCDTASGDLIKVDKTILEDANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIP--- 73
            ||.:|  |||      |::.:|.  .::::...::||.:.||:..:::...||::|..:|||
  Rat    10 LIHVFGKIFC------LLEPNKN--PESHMNVSEIIKYWNYPSLEYEVVTDDGYILPINRIPHGK 66

  Fly    74 --KPGGQPVLLV---HGLLDSSVAYVILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRY 133
              .....|.::|   |||..:...:|...|:.||.|:|::.||||||.|:||:.:::||......
  Rat    67 NNANSSAPKMVVFCQHGLFSTPGVWVANPPDNSLAFILAEAGYDVWLGNSRGSTWAKKHVTLSPD 131

  Fly   134 QPQFWDFSFHELGVYDLPAAIDYVLARSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQA 198
            ..:||.|||.::..|||||.|:::| .:...|||:|:|||.||.......|......:||||...
  Rat   132 SEEFWAFSFDQMIAYDLPATINFIL-NTTGQEQIYYIGHSLGTLIALGAFSTNQELAEKIKLNIL 195

  Fly   199 LAPVVFWDYIDSPIILTFVKYLRPLVFIARSFGIYEFPPENEVWRSLIHKICSFVFQNT-CTYFL 262
            :|||....|:..  ....:.|..|..| ...||..||.| ..|:......:|:....:. |...|
  Rat   196 IAPVRTVKYVKG--FGRLLAYFSPEAF-KLVFGKKEFLP-TVVFSEYSKYVCNIKLVDAGCAGVL 256

  Fly   263 MEAMGVDYAQFNSSLLPLFTGHASSGSSVKSLEHYGQQIHSGGFFKYNYYSTWENRRNHGVDTPP 327
            ....|....|.|:|.:.::..|:.:|:|.:.|.|.||.|.||.|..|::.|...|.:::...|||
  Rat   257 GSLTGFSEDQLNTSRIDVYITHSLAGTSTQILIHAGQAIRSGEFQAYDWGSPSLNMQHYNQTTPP 321

  Fly   328 QYKLTNVDCKVALYYSRNDRLTSDKDVVRLRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLND 392
            .|.:.|:.....::....|.|...|||..|...:.|::.....|:  ::|::||.|.:.||.::|
  Rat   322 LYSVENMKVPTVMFTGLKDFLADPKDVANLVPKIFNLIYHKTIPE--FSHLDFIVGLNAKTEVSD 384

  Fly   393 RMIELMRKVDN 403
            .::.::.:.|:
  Rat   385 EILTILGEYDS 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18302	NP_609420.1	PLN02872	13..399	CDD:215470	120/395 (30%)
		Abhydro_lipase	43..97	CDD:282003	16/61 (26%)
		Abhydrolase_5	79..>208	CDD:289465	51/131 (39%)
Lipo1	XP_006231364.1	Abhydro_lipase	33..94	CDD:282003	16/60 (27%)
		Abhydrolase_1	77..375	CDD:278959	97/304 (32%)
		Abhydrolase_5	77..>199	CDD:289465	48/122 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.810