DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18302 and SPBC14C8.15

DIOPT Version :9

Sequence 1:	NP_609420.1	Gene:	CG18302 / 34452	FlyBaseID:	FBgn0032266	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_595918.1	Gene:	SPBC14C8.15 / 2539842	PomBaseID:	SPBC14C8.15	Length:	460	Species:	Schizosaccharomyces pombe

Alignment Length:	393	Identity:	106/393 - (26%)
Similarity:	182/393 - (46%)	Gaps:	44/393 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EDANLITP-----DLIKKYGYPAETHKIQAKDGFVLTAHRI-PKPGGQ--------PVLLVHGLL 87
            ::||.:|.     ||...:||..|.|.::..||::|..||: .|..|:        |||.:|||:
pombe    64 DNANKLTDARDTIDLCALHGYDLEEHFVRTTDGYLLGLHRVYKKKKGKIEELNYLPPVLFIHGLM 128

  Fly    88 DSSVAYVI-LGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHELGVYDLP 151
            .:|.::|. |..|.::.|.|.:.||||||.|.|||:||.|:.::....|:|||||...:.::|:|
pombe   129 MNSESWVCNLKKEDAIPFALVEQGYDVWLGNLRGNKYSIKNIKFSSQNPKFWDFSLDSIAIFDIP 193

  Fly   152 AAIDYVLARSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQALAPVVFWDYIDSPIILTF 216
            :.:.|:|: ...|:.|..||.|||....|...|..:.....::...||||.:.........:.:.
pombe   194 SIVKYILS-VNSFDSISLVGFSQGAILAFAALSIDTELRNSVRAFIALAPAIAPKKYSGRTVKSI 257

  Fly   217 VKYLRPLVFIARSFGIYEFPPENEVWRSLIHKICSFVFQNTCTYFLMEAMGVDYAQFNSSLLPLF 281
            :.....|:::  .||..........|:::::..   ||......||...:.......:.:...:.
pombe   258 IHANSQLLYL--MFGRNSMLGSAVFWQAVLYPP---VFAKIVDLFLRFFLSWTGKNISETQKIVA 317

  Fly   282 TGHASSGSSVKSLEHYGQ-------QIH--SGGFFKYNYYSTWENRRNHGVDTPPQYKLTNVDCK 337
            ..|..|.:|||...|:.|       |::  |.| ||.:||:        .::...:|.:.|:...
pombe   318 YSHLYSFTSVKCFVHWAQITRRKVLQMYDDSPG-FKPSYYT--------NLNRIARYPIENIRLP 373

  Fly   338 VALYYSRNDRLTSDKDVVRLRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLNDRMIELMRKVD 402
            :.|.|..||.:.   |:..|:..||  .|......|.|.|::.|.|:..|.::..:::|.:..|.
pombe   374 ITLVYGSNDNMV---DIETLKTQLP--PLSQCIQIPNYEHLDIIMGDTKKDIVIQQVVEQLNHVI 433

  Fly   403 NGE 405
            .|:
pombe   434 AGD 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18302	NP_609420.1	PLN02872	13..399	CDD:215470	104/385 (27%)
		Abhydro_lipase	43..97	CDD:282003	22/68 (32%)
		Abhydrolase_5	79..>208	CDD:289465	48/129 (37%)
SPBC14C8.15	NP_595918.1	Abhydro_lipase	75..138	CDD:282003	21/62 (34%)
		Abhydrolase_1	119..412	CDD:278959	84/312 (27%)
		Abhydrolase_5	120..>260	CDD:289465	48/140 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	10	9.770