DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18301 and LIP1

DIOPT Version :9

Sequence 1:	NP_609419.1	Gene:	CG18301 / 34451	FlyBaseID:	FBgn0032265	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_179126.2	Gene:	LIP1 / 816012	AraportID:	AT2G15230	Length:	393	Species:	Arabidopsis thaliana

Alignment Length:	398	Identity:	113/398 - (28%)
Similarity:	188/398 - (47%)	Gaps:	38/398 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 FQLAIPSSVLEDAHLNTI--QLISKYGYPAENYTVQSDDGYLLGLFRIARPG-----ALPVLLVH 87
            |.....|.:|..:.:|::  .||....|....:::|:.|||:|.|.|:|..|     ..||||.|
plant    15 FSALTQSHLLHGSPVNSLCADLIHPANYSCTEHSIQTKDGYILALQRVASLGPRLQSGPPVLLQH 79

  Fly    88 GLMDSSDTWVMMGPSSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAEDSDFWNFSFHEMGIFD 152
            ||..:.|.|.:..|..|||::|.:.|:|||:.||||..|:..||..|..|.:||::|:.::.::|
plant    80 GLFMAGDVWFLNSPKESLGFILADHGFDVWVGNVRGTRYSYGHVTLSDTDKEFWDWSWQDLAMYD 144

  Fly   153 LPAIIDYILMQSGFGQLHYIGHSQGSTIFWILASERPEYMEKIVMMQALAPVAFLSHCRSPIVNL 217
            |..:|.|:...|. .::..:||||| ||....|..:|...|.:.....|.|:::|.|..:|:|..
plant   145 LAEMIQYLYSISN-SKIFLVGHSQG-TIMSFAALTQPHVAEMVEAAALLCPISYLDHVTAPLVER 207

  Fly   218 LASQDTAVASFLSAAGYNEFLPSNSVIDQFKRYA---------CRDIISSSVCQSLFFILFGFNG 273
            :....  :...:.|.|.::.   |...|...:..         |.|.::|....:..|
plant   208 MVFMH--LDQMVVALGLHQI---NFRSDMLVKLVDSLCEGHMDCTDFLTSITGTNCCF------- 260

  Fly   274 QQVNQTMLPIVVGHTPAGASIRQMHHYGQLRNSGKFQQFDYGLL-NFLHYGSLSPPPYELEKVKA 337
               |.:.:...:.:.|..:|::.:.|..|:...|.|.|:|||.. |...||...||.:.|..:.|
plant   261 ---NASKIEYYLDYEPHPSSVKNIRHLFQMIRKGTFAQYDYGYFKNLRTYGLSKPPEFILSHIPA 322

  Fly   338 KVAIY--YAKNDWIAPPEDVDMLFNRLPNVVEKYLVPNENFNHFDLVWGRDAKRILWNRMLGVMQ 400
            .:.::  |...|.:|...||:.....||:..|  |:..|::.|.|.|.|..||..::..|:...:
plant   323 SLPMWMGYGGTDGLADVTDVEHTLAELPSSPE--LLYLEDYGHIDFVLGSSAKEDVYKHMIQFFR 385

  Fly   401 SVVPYSSY 408
            :.|..||:
plant   386 AKVKSSSW 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18301	NP_609419.1	Abhydro_lipase	46..100	CDD:282003	21/60 (35%)
		PLN02872	48..407	CDD:215470	107/375 (29%)
		Abhydrolase_5	82..225	CDD:289465	51/142 (36%)
		Abhydrolase_5	<327..379	CDD:289465	14/53 (26%)
LIP1	NP_179126.2	PLN02872	6..393	CDD:215470	112/396 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D651396at2759
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.970