DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18301 and lipa

DIOPT Version :9

Sequence 1:	NP_609419.1	Gene:	CG18301 / 34451	FlyBaseID:	FBgn0032265	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001015847.2	Gene:	lipa / 548564	XenbaseID:	XB-GENE-952977	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	368	Identity:	131/368 - (35%)
Similarity:	211/368 - (57%)	Gaps:	13/368 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 DAHLNTIQLISKYGYPAENYTVQSDDGYLLGLFRI------ARPGALPVL-LVHGLMDSSDTWVM 98
            :|.:|..:||...|||:|.|.|.::|||:|.:.||      |..|..||: |.|||:.....||.
Frog    44 EATMNISELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVT 108

  Fly    99 MGPSSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAEDSDFWNFSFHEMGIFDLPAIIDYILMQ 163
            ...::|||::|.:.|||||:.|.||||::::|...|.:..:||.||:.|:...||||::|:|..:
Frog   109 NLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKK 173

  Fly   164 SGFGQLHYIGHSQGSTIFWILASERPEYMEKIVMMQALAPVAFLSHCRSPIVNLLASQDTAVASF 228
            :|..|:.|:|||||:||.:|..|..|:..:||.|...|||||.:...:||:..|....:..:...
Frog   174 TGQEQIFYVGHSQGTTIAFIAFSSLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVLPEFLIEEL 238

  Fly   229 LSAAGYNEFLPSNSVIDQFKRYACRDIISSSVCQSLFFILFGFNGQQVNQTMLPIVVGHTPAGAS 293
            .   |..||||...:|.....:.|...|:..:|.::||:|.|||.:.:|.:.:.:...|.|||.|
Frog   239 F---GKGEFLPQTYLITWLATHFCTHAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAGTS 300

  Fly   294 IRQMHHYGQLRNSGKFQQFDYGLL-NFLHYGSLSPPPYELEKVKAKVAIYYAKNDWIAPPEDVDM 357
            ::.|.|:.|...||:.:.||:|.. |.:||...:||.|.:..:....|::...|||:|..:||.:
Frog   301 VQNMLHWRQGVRSGELKAFDFGTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVAL 365

  Fly   358 LFNRLPNVVEKYLVPNENFNHFDLVWGRDAKRILWNRMLGVMQ 400
            |..::.|:|....:|  ::.|.|.:||.||...::|.::.:|:
Frog   366 LLTQVSNLVYHKEIP--DWEHLDFIWGLDAPERMYNEIIAMMK 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18301	NP_609419.1	Abhydro_lipase	46..100	CDD:282003	24/60 (40%)
		PLN02872	48..407	CDD:215470	129/361 (36%)
		Abhydrolase_5	82..225	CDD:289465	59/143 (41%)
		Abhydrolase_5	<327..379	CDD:289465	14/51 (27%)
lipa	NP_001015847.2	Abhydro_lipase	49..110	CDD:282003	24/60 (40%)
		PLN02872	50..409	CDD:215470	129/362 (36%)
		Abhydrolase_5	91..>229	CDD:289465	59/137 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm47739
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.030