DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18301 and lipf

DIOPT Version :9

Sequence 1:	NP_609419.1	Gene:	CG18301 / 34451	FlyBaseID:	FBgn0032265	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_998569.1	Gene:	lipf / 406713	ZFINID:	ZDB-GENE-040426-2737	Length:	396	Species:	Danio rerio

Alignment Length:	387	Identity:	133/387 - (34%)
Similarity:	215/387 - (55%)	Gaps:	24/387 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 QLAIPSSVLE-DAHLNTIQLISKYGYPAENYTVQSDDGYLLGLFRI----------ARPGALPVL 84
            |.|:..:.|: :.::|..::|..:|||||.:.|.::|||:|.:.||          .:|   .|.
Zfish    20 QSALDGTGLDPEVNMNISEIIRHWGYPAEEFEVVTEDGYILSINRIPHGVKNKNEEVKP---VVF 81

  Fly    85 LVHGLMDSSDTWVMMGPSSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAEDSDFWNFSFHEMG 149
            |.|||:.:...||...|::|||::|.:.|:|||:.|.||||::.:||.......::|.||..||.
Zfish    82 LQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRGNTWSCKHVSLDPRQKEYWKFSHDEMA 146

  Fly   150 IFDLPAIIDYILMQSGFGQLHYIGHSQGSTIFWILASERPEYMEKIVMMQALAPVAFLSHCRSPI 214
            ..||||:|::|...:|..|:.|:|||||:||.::..|..||...||.|..||||||.:...:||:
Zfish   147 KKDLPAVINFITKMTGQEQIFYVGHSQGTTIAFMAFSTMPELASKIKMFFALAPVATVGMTKSPM 211

  Fly   215 VNLLASQDTAVASFL--SAAGYNEFLPSNSVIDQFKRYACRDIISSSVCQSLFFILFGFNGQQVN 277
            ..|     :.:..||  ...|..:|.|.|.:|..|....|.....|.:|.::||:|.||:.:.:|
Zfish   212 TKL-----SVIPEFLIWDLFGQKDFFPQNELIKFFATEFCSRKPLSVLCGNVFFLLCGFDEKNLN 271

  Fly   278 QTMLPIVVGHTPAGASIRQMHHYGQLRNSGKFQQFDYGLL-NFLHYGSLSPPPYELEKVKAKVAI 341
            .:..|:...|.|||.|::.|.|:.|...|.|...:|||.. |..||...:||.|.::.:....|:
Zfish   272 MSRTPVYTAHCPAGTSVQNMIHWAQAVKSSKLMAYDYGRAGNMAHYNQSTPPLYNIQDMMVPTAV 336

  Fly   342 YYAKNDWIAPPEDVDMLFNRLPNVVEKYLVPNENFNHFDLVWGRDAKRILWNRMLGVMQSVV 403
            :....|.:|.|:||.:|..::|.:|.|..:  :::.|.|.:||.||.:.::.:|:.:|:..|
Zfish   337 WSGGQDTLADPKDVALLLTQIPKLVYKRDI--KHWEHLDFIWGMDAPQEMYEKMIEIMRENV 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18301	NP_609419.1	Abhydro_lipase	46..100	CDD:282003	21/63 (33%)
		PLN02872	48..407	CDD:215470	129/369 (35%)
		Abhydrolase_5	82..225	CDD:289465	59/142 (42%)
		Abhydrolase_5	<327..379	CDD:289465	13/51 (25%)
lipf	NP_998569.1	PLN02872	4..393	CDD:215470	131/382 (34%)
		Abhydro_lipase	36..97	CDD:282003	21/63 (33%)
		Abhydrolase_5	78..242	CDD:289465	67/171 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574741
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	265	1.000	Inparanoid score	I3034
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm26515
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.810