DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18301 and Lip4

DIOPT Version :9

Sequence 1:	NP_609419.1	Gene:	CG18301 / 34451	FlyBaseID:	FBgn0032265	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001260356.1	Gene:	Lip4 / 34450	FlyBaseID:	FBgn0032264	Length:	448	Species:	Drosophila melanogaster

Alignment Length:	370	Identity:	222/370 - (60%)
Similarity:	290/370 - (78%)	Gaps:	2/370 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IPSSVLEDAHLNTIQLISKYGYPAENYTVQSDDGYLLGLFRIARPGALPVLLVHGLMDSSDTWVM 98
            :..::.||:||||..||.||||||||:|:::||||:|.|.|||||||.||||||||:|||.||||
  Fly    73 VDPNIQEDSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRIARPGATPVLLVHGLLDSSATWVM 137

  Fly    99 MGPSSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAEDSDFWNFSFHEMGIFDLPAIIDYILMQ 163
            |||:..|||:||:|||||||||||||||:::||:||...:.||:|:|||||..|:||.:||||..
  Fly   138 MGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEMGKHDIPATMDYILNS 202

  Fly   164 SGFGQLHYIGHSQGSTIFWILASERPEYMEKIVMMQALAPVAFLSHCRSPIVNLLASQDTAVASF 228
            :|..||||||||||:.:|||:|||:||||:||::||.|||||||.|||||:||.||....:|:..
  Fly   203 TGVSQLHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVAFLKHCRSPVVNFLAEWHLSVSLV 267

  Fly   229 LSAAGYNEFLPSNSVIDQFKRYACRD-IISSSVCQSLFFILFGFNGQQVNQTMLPIVVGHTPAGA 292
            |...|.:||||.|..|..|.|..|.: .|:..:|.::.|:..||:..|:|:||||::|||:||||
  Fly   268 LKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTTGFDKLQLNETMLPVIVGHSPAGA 332

  Fly   293 SIRQMHHYGQLRNSGKFQQFDYG-LLNFLHYGSLSPPPYELEKVKAKVAIYYAKNDWIAPPEDVD 356
            |.:||.|:|||..||.|:|:|:| |.|...||::.||.|.||.|:||||:||.:|||:||||||:
  Fly   333 STKQMQHFGQLNRSGGFRQYDHGWLRNHWIYGTIDPPSYHLENVRAKVALYYGQNDWLAPPEDVE 397

  Fly   357 MLFNRLPNVVEKYLVPNENFNHFDLVWGRDAKRILWNRMLGVMQS 401
            ||..:||||||||||.::.|||.|.:||.||:.:||:|||.:|::
  Fly   398 MLNRKLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRMLEIMRN 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18301	NP_609419.1	Abhydro_lipase	46..100	CDD:282003	40/53 (75%)
		PLN02872	48..407	CDD:215470	216/356 (61%)
		Abhydrolase_5	82..225	CDD:289465	98/142 (69%)
		Abhydrolase_5	<327..379	CDD:289465	35/51 (69%)
Lip4	NP_001260356.1	PLN02872	88..446	CDD:215470	216/355 (61%)
		Abhydro_lipase	88..139	CDD:282003	39/50 (78%)
		Abhydrolase_5	121..>253	CDD:289465	93/131 (71%)
		Abhydrolase_5	<368..419	CDD:289465	34/50 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438223
Domainoid	1	1.000	104	1.000	Domainoid score	I6695
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	1	1.000	-	-		H28267
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D29915at7147
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm26515
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	12	11.800