DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18301 and lipl-8

DIOPT Version :9

Sequence 1:	NP_609419.1	Gene:	CG18301 / 34451	FlyBaseID:	FBgn0032265	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_506641.1	Gene:	lipl-8 / 190108	WormBaseID:	WBGene00013050	Length:	401	Species:	Caenorhabditis elegans

Alignment Length:	365	Identity:	107/365 - (29%)
Similarity:	179/365 - (49%)	Gaps:	34/365 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LNTIQLISKYGYPAENYTVQSDDGYLLGLFRI-------------ARPGALPVLLVHGLMDSSDT 95
            |:....||.|||..|.:.|.:||||.:.|.||             .||   .|..:|||..||..
Worm    23 LDAADTISHYGYTVEKHYVTTDDGYTVQLQRIPVGRDDRSILGCSKRP---VVFFMHGLFGSSYH 84

  Fly    96 WVMMGPSSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAEDSDFWNFSFHEMGIFDLPAIIDYI 160
            :::..||.|..|:..:.|:|||:.|:||..|...|..:|....:|||||.:|...:||...|:|:
Worm    85 FLLNLPSQSAAYIFADAGFDVWLGNIRGTEYGLNHTSFSTNGVNFWNFSLYEHSHYDLRQQIEYV 149

  Fly   161 LMQSGFGQLHYIGHSQGSTI-FWILASERPEYMEKIVMMQALAPVA-FLSHCRSPIVNLLASQDT 223
            |..:....|.|:|||||:.: |..||.....:..||.:..||.|.| |:    .|::.....::.
Worm   150 LDYTRHESLFYVGHSQGTAVMFARLAEADVTWQSKIRVFFALGPTAGFM----KPLMPFTLLEEN 210

  Fly   224 AVASFLSAAGYNEF--LP---SNSVIDQFKRYACRDIISSSVCQSLFFILFGFNG-QQVNQTMLP 282
            .:.:.:..|...:|  ||   ..::..:|..: |.....:.:|.:.|.:..|... .|||.:.:|
Worm   211 YLQALIQFALDGKFGILPVEIPRAIASKFADF-CSSKFFTFLCSAGFKVAAGIETLGQVNDSRIP 274

  Fly   283 IVVGHTPAGASIRQMHHYGQLRNSGKFQQFDYGLL-NFLHYGSLSPPPYELEKVKAKVAIYYAKN 346
            |::.|.|:..|...:.|:.|:....:.::.|.|.. |.:.||....|..|:..:.|:..:|::|:
Worm   275 IILSHFPSATSTLNLLHWMQIFKYHELRRLDLGTARNLIAYGQKDAPRLEIGNIIAQTILYFSKD 339

  Fly   347 DWIAPPEDV-DMLFNRL-PNVVEKYLVPNENFNHFDLVWG 384
            |.|....|| :::..:: |.::|.|.:  ::|.|||.:.|
Worm   340 DQITDEVDVREIIMKQMGPGLIESYDL--DHFTHFDFILG 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18301	NP_609419.1	Abhydro_lipase	46..100	CDD:282003	22/66 (33%)
		PLN02872	48..407	CDD:215470	106/361 (29%)
		Abhydrolase_5	82..225	CDD:289465	49/144 (34%)
		Abhydrolase_5	<327..379	CDD:289465	13/53 (25%)
lipl-8	NP_506641.1	PLN02872	26..401	CDD:215470	106/362 (29%)
		Abhydro_lipase	26..89	CDD:282003	22/65 (34%)
		Abhydrolase_5	71..>193	CDD:289465	45/121 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930