DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lip4 and Lipf

DIOPT Version :9

Sequence 1:	NP_001260356.1	Gene:	Lip4 / 34450	FlyBaseID:	FBgn0032264	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_080610.1	Gene:	Lipf / 67717	MGIID:	1914967	Length:	395	Species:	Mus musculus

Alignment Length:	372	Identity:	143/372 - (38%)
Similarity:	218/372 - (58%)	Gaps:	19/372 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 DSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRI-------ARPGATPV-LLVHGLLDSSATWV 136
            ::::|...:|..:|||:|.:.:.|:|||||.::||       ...|..|| .|.|||:.|:..|:
Mouse    29 EANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKKNSENIGKRPVAYLQHGLIASATNWI 93

  Fly   137 MMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEMGKHDIPATMDYILN 201
            ...||..|.::|.|.|||||:.|.||||:|||:|.||....:||.|:|.||.|:|:|||:|:|:.
Mouse    94 TNLPNNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATIDFIVQ 158

  Fly   202 STGVSQLHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVAFLKHCRSPV--VNFLAEWHLSV 264
            .||..::||:||||||.:.:|..|..|....||.....|||||.:|:..||.  ::.:.::.|.|
Mouse   159 KTGQEKIHYVGHSQGTTIGFIAFSTNPALAKKIKRFYALAPVATVKYTESPFKKISLIPKFLLKV 223

  Fly   265 SLVLKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTTGFDKLQLNETMLPVIVGHSP 329
                 :.|...|:|.|.........:|....:.. :|||.:|:..||||..||.:...|.:||:|
Mouse   224 -----IFGNKMFMPHNYLDQFLGTEVCSRELLDL-LCSNALFIFCGFDKKNLNVSRFDVYLGHNP 282

  Fly   330 AGASTKQMQHFGQLNRSGGFRQYDHGW-LRNHWIYGTIDPPSYHLENVRAKVALYYGQNDWLAPP 393
            ||.||:.:.|:.||.:||..:.|:.|. |:|...|....||.|.:..:...:|::.|.:|.||.|
Mouse   283 AGTSTQDLFHWAQLAKSGKLQAYNWGSPLQNMLHYNQKTPPYYDVSAMTVPIAVWNGGHDILADP 347

  Fly   394 EDVEMLNRKLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRMLEIM 440
            :||.||..||||::  |..:...:|||||||.:||.:.:::.::.:|
Mouse   348 QDVAMLLPKLPNLL--YHKEILPYNHLDFIWAMDAPQEVYNEIVTMM 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip4	NP_001260356.1	PLN02872	88..446	CDD:215470	142/364 (39%)
		Abhydro_lipase	88..139	CDD:282003	22/58 (38%)
		Abhydrolase_5	121..>253	CDD:289465	64/132 (48%)
		Abhydrolase_5	<368..419	CDD:289465	18/50 (36%)
Lipf	NP_080610.1	PLN02872	35..389	CDD:215470	141/361 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831806
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8736
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1506
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.840