DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lip4 and Gm8978

DIOPT Version :9

Sequence 1:	NP_001260356.1	Gene:	Lip4 / 34450	FlyBaseID:	FBgn0032264	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_001310180.1	Gene:	Gm8978 / 668106	MGIID:	3647649	Length:	399	Species:	Mus musculus

Alignment Length:	388	Identity:	131/388 - (33%)
Similarity:	212/388 - (54%)	Gaps:	24/388 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 VDPNIQEDSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRIAR-----PGATPVLLV---HGLL 129
            :..|...:|::|...:||.:.||:|.:.:.|||||||.::||..     ....|.::|   |||.
Mouse    21 IGQNKNPESNMNVSEIIKHWEYPSEEYEVVTDDGYILPINRIPHGKNNANSTAPKMVVFCLHGLF 85

  Fly   130 DSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEMGKHDIPA 194
            .::..||...|:..|.::|.|.|||||:.|.||:|.::|||..:|...:||.|::.||.|:|:||
Mouse    86 STAGIWVSNPPDNSLAFILADAGYDVWLGNNRGSTRAKKHVTLNTDSKEFWAFSYDEMIKYDLPA 150

  Fly   195 TMDYILNSTGVSQLHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVAFLKHC----RSPVVN 255
            .:.:||..||..|::|.||||||::.....:...|..:||.|...:|||..:|:.    |.|.
Mouse   151 IIKFILEKTGQKQIYYTGHSQGTLIALGAFATNQELAEKIKLSILIAPVHTVKYVKGAGRLPA-- 213

  Fly   256 FLAEWHLSVSLVLKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTTGFDKLQLNETM 320
                 :.:.:....:.|..||.|...| |..::.:|| ..:....|:.|:...||:...|.|.:.
Mouse   214 -----YFTPTAFKIVFGEKEFFPTKVF-SRLSQHVCD-IKLVDAGCATVLGSLTGYSPEQFNTSR 271

  Fly   321 LPVIVGHSPAGASTKQMQHFGQLNRSGGFRQYDHGW-LRNHWIYGTIDPPSYHLENVRAKVALYY 384
            :.|.:.||...:|.:.:.|:||..|||.|:.||.|. ..|...|....||.|::|:::...|::.
Mouse   272 IDVYITHSLGESSIQILIHYGQAIRSGVFQAYDWGSPSLNMQHYNQTTPPVYNVEDMKVPTAMFS 336

  Fly   385 GQNDWLAPPEDVEMLNRKLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRMLEIMRNHENSI 447
            |..|:|:.||||..|..|:.|:....::.|  |:|||||.|::||:.:.:.:|.|:|.::..|
Mouse   337 GLKDFLSNPEDVANLVPKISNLTYHKIISD--FSHLDFIMGLNARKEVSEEILTILRKYDGDI 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip4	NP_001260356.1	PLN02872	88..446	CDD:215470	127/370 (34%)
		Abhydro_lipase	88..139	CDD:282003	21/58 (36%)
		Abhydrolase_5	121..>253	CDD:289465	54/138 (39%)
		Abhydrolase_5	<368..419	CDD:289465	17/50 (34%)
Gm8978	NP_001310180.1	PLN02872	17..391	CDD:215470	129/380 (34%)
		Abhydro_lipase	33..94	CDD:282003	21/60 (35%)
		Abhydrolase_5	77..242	CDD:289465	60/172 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831865
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8736
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.910