DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lip4 and CG17097

DIOPT Version :9

Sequence 1:	NP_001260356.1	Gene:	Lip4 / 34450	FlyBaseID:	FBgn0032264	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_609429.1	Gene:	CG17097 / 34461	FlyBaseID:	FBgn0265264	Length:	1087	Species:	Drosophila melanogaster

Alignment Length:	387	Identity:	167/387 - (43%)
Similarity:	239/387 - (61%)	Gaps:	15/387 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 FKTPTFLGRSVAVDSNVRLENDVDPNIQEDSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRIA 115
            ||||.:|               ...:|.:::.|.|..||:|||||:|.:.:.::|||.|.||||.
  Fly   707 FKTPNYL---------------TQEDILDNTKLTTVDLIEKYGYPSETNYVTSEDGYRLCLHRIP 756

  Fly   116 RPGATPVLLVHGLLDSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFW 180
            ||||.||||||||:.|||:||.:||..||.|:||.:||||||.|.|||.|||:::.......|:|
  Fly   757 RPGAEPVLLVHGLMASSASWVELGPKDGLAYILYRKGYDVWMLNTRGNIYSRENLNRRLKPNKYW 821

  Fly   181 DFTFHEMGKHDIPATMDYILNSTGVSQLHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVAF 245
            ||:|||:||.|:||.:|:||..|...::.|||||||:.||::|.||:|.|..|:.|||.|:|..:
  Fly   822 DFSFHEIGKFDVPAAIDHILIHTHKPKIQYIGHSQGSTVFFVMCSERPNYAHKVNLMQALSPTVY 886

  Fly   246 LKHCRSPVVNFLAEWHLSVSLVLKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTTG 310
            |:..||||:.||..:....|::|.|:|.:|...|.:.|..|.:.||..:.:...||:...|:..|
  Fly   887 LQENRSPVLKFLGMFKGKYSMLLNLLGGYEISAKTKLIQQFRQHICSGSELGSSICAIFDFVLCG 951

  Fly   311 FDKLQLNETMLPVIVGHSPAGASTKQMQHFGQLNRSGGFRQYDHGWLRNHWIYGTIDPPSYHLEN 375
            ||....|.|:.|::..|:..|||.||:.|:.||.....|:::|||.:.|...|.:.:||:|:|..
  Fly   952 FDWKSFNTTLTPIVAAHASQGASAKQIYHYAQLQGDLNFQRFDHGAVLNRVRYESSEPPAYNLSQ 1016

  Fly   376 VRAKVALYYGQNDWLAPPEDVEMLNRKLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRML 437
            ..:||.|::|:.|||....||..|..:|||:||...|:.:.|:|.||....|.|.||:..:|
  Fly  1017 TTSKVVLHHGEGDWLGSTSDVIRLQERLPNLVESRKVNFEGFSHFDFTLSKDVRPLLYSHVL 1078

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip4	NP_001260356.1	PLN02872	88..446	CDD:215470	159/350 (45%)
		Abhydro_lipase	88..139	CDD:282003	33/50 (66%)
		Abhydrolase_5	121..>253	CDD:289465	72/131 (55%)
		Abhydrolase_5	<368..419	CDD:289465	21/50 (42%)
CG17097	NP_609429.1	Abhydro_lipase	726..780	CDD:282003	34/53 (64%)
		MhpC	746..1061	CDD:223669	143/314 (46%)
		Abhydrolase_5	762..>899	CDD:289465	75/136 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438233
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850