DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lip4 and lipl-3

DIOPT Version :9

Sequence 1:	NP_001260356.1	Gene:	Lip4 / 34450	FlyBaseID:	FBgn0032264	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_503233.1	Gene:	lipl-3 / 178572	WormBaseID:	WBGene00020016	Length:	404	Species:	Caenorhabditis elegans

Alignment Length:	436	Identity:	142/436 - (32%)
Similarity:	218/436 - (50%)	Gaps:	52/436 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 SLCLLQSGIVEGISLSLGDITLFNVNFKTPTFLGRSVAVDSNVRLENDVDPNIQEDSHLNTYSLI 89
            |||          :|.|..:.:.||:.|:                    ||.:    |:.|..:|
Worm     4 SLC----------ALLLVILAVHNVHAKS--------------------DPEL----HMTTPQII 34

  Fly    90 KKYGYPAENHTLETDDGYILTLHRIAR--------PGATPVLLV-HGLLDSSATWVMMGPNKGLG 145
            :::||||..:::.|||||||.||||..        .|..||:.: ||||.:|..|.|..|.:...
Worm    35 ERWGYPAMIYSVTTDDGYILELHRIPHGKTNVTWPNGKQPVVFMQHGLLCASTDWTMNLPEQSAA 99

  Fly   146 YLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEMGKHDIPATMDYILNSTGVSQLHY 210
            ::..|.|:|||:.|:||||||.||......|:.||::::.||..:|:||.:|.:|..||...|:|
Worm   100 FIFADAGFDVWLGNMRGNTYSMKHKNLKASHSDFWEWSWDEMATYDLPAMIDKVLEVTGQESLYY 164

  Fly   211 IGHSQGTV-VFWIMASEKPEYMDKIILMQGLAPVAFLKHCRSPVVNFLAEWHLSVSLVLKLIGVH 274
            :||||||: :|..::.:...:..||.....||||..:|..:..:..|...:.|.......:.|..
Worm   165 MGHSQGTLTMFSHLSKDDGIFAKKIKKFFALAPVGSVKDIKGFLSFFAHYFSLEFDGWFDVFGAG 229

  Fly   275 EFLPKNEFISMFNRIICDETTITKEICSNVIFLTTGFDKLQLNETMLPVIVGHSPAGASTKQMQH 339
            ||||.|..:.:..:.||....|..::|.||.||..|.:..|.|.|.:||...|.|||.:|:.:.|
Worm   230 EFLPNNWAMKLAAKDICGGLKIESDLCDNVCFLIAGPESDQWNSTRVPVYASHDPAGTATQNIVH 294

  Fly   340 FGQLNRSGGFRQYDHGWLRNHWIYGTIDPPSYHLENVR-AKVALYYGQNDWLAPPEDVE--MLNR 401
            :.|:.|.||...||.|...|...||..:||.|....:: .::.||:...||||...|:.  :|.|
Worm   295 WIQMVRHGGVPAYDWGSKENKKKYGQANPPEYDFTAIKGTQIYLYWSDADWLADKTDITNYLLTR 359

  Fly   402 KLPNVV--EKYLVDDKEFNHLDFIWGIDARELLWDRMLEIMRNHEN 445
            ..|.::  ..|..|   :||.||::|:.|...::..:::|.....|
Worm   360 LNPAIIAQNNYFTD---YNHFDFVFGLRAPNDIYLPIVDICTKDYN 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lip4	NP_001260356.1	PLN02872	88..446	CDD:215470	130/373 (35%)
		Abhydro_lipase	88..139	CDD:282003	26/59 (44%)
		Abhydrolase_5	121..>253	CDD:289465	52/133 (39%)
		Abhydrolase_5	<368..419	CDD:289465	15/55 (27%)
lipl-3	NP_503233.1	PLN02872	10..390	CDD:215470	136/406 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156599
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm4823
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.760