DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lrr47 and PIRL4

DIOPT Version :9

Sequence 1:	NP_001260355.1	Gene:	Lrr47 / 34449	FlyBaseID:	FBgn0010398	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_195272.1	Gene:	PIRL4 / 829699	AraportID:	AT4G35470	Length:	549	Species:	Arabidopsis thaliana

Alignment Length:	321	Identity:	76/321 - (23%)
Similarity:	140/321 - (43%)	Gaps:	55/321 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 DGKTTIGF-----IQP------PDNLLIKCDPIQL--KGFL----------QTLKLGMDGKDAIN 118
            |.::::.|     ::|      .|:.:.|..|..|  .||.          .||..|.||:....
plant   143 DSQSSLNFSERAPVRPKDMVSRDDSFVTKSKPSSLYSDGFAAPPRRPQILDSTLTTGNDGEKLSL 207

  Fly   119 LRLNINAATAIPQKAQPQVRMV-ISKRSEYPIKGFP------RTLKSLTINNSQLVKLSFEICTL 176
            ::|    |:.|...|:...:.: :..:....::..|      .:|.||.::.:.:|.|...|..|
plant   208 IKL----ASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKLSSLTSLDLSENHIVVLPNTIGGL 268

  Fly   177 RNLTKLDVSGNKLTKIPSELGR-LPLTSLHLGNNLLGTQNDWCWLRGTKLCQSLGELDLSGNGLT 240
            .:|||||:..|::.::|..:|. |.|..|:||:|.|.:...    ..::|.: |.|||||.|.|.
plant   269 SSLTKLDLHSNRIGQLPESIGELLNLVYLNLGSNQLSSLPS----AFSRLVR-LEELDLSCNNLP 328

  Fly   241 YFPPPLVKFESLVSLNLNNNLLSRLPFAIRRMKALRKLYVCSNELESLPSAVEDL-RIDLLDVWG 304
            ..|..:....||..|::..|.:..:|::|....:|.:|....|:|::||.|:..: .:::|.|..
plant   329 ILPESIGSLVSLKKLDVETNDIEEIPYSIGGCSSLIELRADYNKLKALPEAIGKITTLEILSVRY 393

  Fly   305 NCFKEFNADAAQQMYLQK------AASNSPQPLWL--------LGARAVDKYMLPLSAGSI 351
            |..::.....:....|::      ...:.|:.|..        :|....|...||.|.|::
plant   394 NNIRQLPTTMSSLASLKELDVSFNELESVPESLCFATTLVKLNIGNNFADMVSLPRSIGNL 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lrr47	NP_001260355.1	LRR_8	154..211	CDD:290566	21/57 (37%)
		LRR_4	156..194	CDD:289563	13/37 (35%)
		leucine-rich repeat	156..178	CDD:275380	7/21 (33%)
		leucine-rich repeat	179..199	CDD:275380	8/20 (40%)
		leucine-rich repeat	201..228	CDD:275380	7/26 (27%)
		leucine-rich repeat	229..274	CDD:275380	15/44 (34%)
		leucine-rich repeat	275..298	CDD:275380	7/23 (30%)
PIRL4	NP_195272.1	LRR	194..>471	CDD:227223	67/270 (25%)
		leucine-rich repeat	271..293	CDD:275380	8/21 (38%)
		leucine-rich repeat	294..316	CDD:275380	7/25 (28%)
		leucine-rich repeat	317..339	CDD:275380	9/21 (43%)
		leucine-rich repeat	340..362	CDD:275380	5/21 (24%)
		leucine-rich repeat	363..385	CDD:275380	7/21 (33%)
		leucine-rich repeat	386..408	CDD:275380	3/21 (14%)
		leucine-rich repeat	409..431	CDD:275380	3/21 (14%)
		leucine-rich repeat	432..456	CDD:275380	6/23 (26%)
		leucine-rich repeat	457..479	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910