Protein Alignment Lrr47 and lrr-1

DIOPT Version :9

• Sequence 1: NP_001260355.1
• Gene: Lrr47 / 34449
• FlyBaseID: FBgn0010398
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_494928.1
• Gene: lrr-1 / 173869
• WormBaseID: WBGene00018016
• Length: 453
• Species: Caenorhabditis elegans
• Alignment Length: 478
• Identity: 98/478 - (20%)
• Similarity: 179/478 - (37%)
• Gaps: 120/478 - (25%)

  Fly     1 MKILCEVQVVNRATQTNKTPRPVKSTLAIGYKQSARDANGNTKKELEMVLFSGQNKTGNRYKVKD 65
            |::.|||............|:|.||.......|..|    .|..:.::.:....:||||:::: :
 Worm     1 MRLPCEVVFARYKANAGVNPKPTKSQKGFVILQKLR----QTPPQYQITVAVAGDKTGNKFEL-N 60

  Fly    66 NIHVVHTKFVLDGKTTIGFIQPPDNL--LIKCDPIQLKGFLQTLKLGMDGKDAINLRLNINAATA 128
            ...::..||:..|||||.|...|..:  :.|.:|..|...::.::..:.|::.
 Worm    61 KPPIILDKFIAQGKTTITFQTTPAVMVCISKANPEALAQLIEAIRKIVKGENV------------ 113

  Fly   129 IPQKAQPQVRMVISKRSEYPIKGFPRTLKSLTINNSQLVKLSFEIC-----TLR----------- 177
                   .:..|..|.|::.    |.|   :|:||....|...:.|     ||:
 Worm   114 -------DIEKVKVKSSDFK----PTT---ITVNNQATYKKQMQSCSEFLKTLKIEPIDLRRPDK 164

  Fly   178 ------NLTKLDVSGN-------------KLTKIPS------ELGRLPLTSLHLGNNLLGTQNDW 217
                  |||:|.::||             ||.::.|      .|..:|:.::
 Worm   165 AWRFCHNLTRLTLNGNPIGAHNRDLDVFSKLKQLQSLEMRSCSLELIPVPAM------------- 216

  Fly   218 CWLRGTKLCQSLGELDLSGNGLTYFPPPLVKFESLVSLNLNNNLLSRLPFAIRRMKALRKLYVCS 282
            |.: ..:|..|:..||...|.|:.| ||:...:.|..:|..:|.:..||..|..::.|..:.|.:
 Worm   217 CTM-FRELPTSISLLDFGDNHLSIF-PPIFHLKQLKIINAAHNAIKYLPSRIGVLQNLNTIDVSN 279

  Fly   283 NELESLP------SAVEDLRIDLLDVWGNCFKEFNADAAQQMY-----LQKAASNSPQPLWLLGA 336
            |.:.:||      .::|.:.|:..|......:|......:::.     ::.........|..:.|
 Worm   280 NLMTALPYVFSKIPSIEHVGINANDQMVRLEEEIGPIFIRRLLTKVDNIEYTHEGGVDKLGTIAA 344

  Fly   337 RAV-----------DKYMLPLSAGSIPAVLIDLIREAPRCPCGELCY-AQRKEDLFQRVVQPKFI 389
            .|:           .:..|||   |:...:.||:.|.|.....|||. ..|...:  |.::|..|
 Worm   345 NAIHREECSKSMKFGRQFLPL---SLRFDMDDLMFEKPGISSLELCTGCVRLRHI--RYIRPLII 404

  Fly   390 TVKNLTYSRE---HQIYADVVLC 409
            ..:.:..|.:   ..:..|.:||
 Worm   405 QSRQIANSVDVIGRFVTFDRLLC 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lrr47	NP_001260355.1	LRR_8	154..211	CDD:290566	19/97 (20%)
		LRR_4	156..194	CDD:289563	15/72 (21%)
		leucine-rich repeat	156..178	CDD:275380	7/43 (16%)
		leucine-rich repeat	179..199	CDD:275380	9/38 (24%)
		leucine-rich repeat	201..228	CDD:275380	2/26 (8%)
		leucine-rich repeat	229..274	CDD:275380	13/44 (30%)
		leucine-rich repeat	275..298	CDD:275380	6/28 (21%)
lrr-1	NP_494928.1	LRR	<146..>303	CDD:227223	36/171 (21%)
		LRR_RI	149..>303	CDD:238064	36/168 (21%)
		leucine-rich repeat	172..197	CDD:275380	7/24 (29%)
		leucine-rich repeat	198..226	CDD:275380	5/41 (12%)
		leucine-rich repeat	227..248	CDD:275380	7/21 (33%)
		leucine-rich repeat	249..271	CDD:275380	6/21 (29%)
		leucine-rich repeat	272..294	CDD:275380	5/21 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48628
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007359
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3791
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950