Protein Alignment Myo31DF and myo1b

DIOPT Version :9

• Sequence 1: NP_001188784.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: XP_005168005.1
• Gene: myo1b / 541515
• ZFINID: ZDB-GENE-030131-695
• Length: 1167
• Species: Danio rerio
• Alignment Length: 1180
• Identity: 442/1180 - (37%)
• Similarity: 632/1180 - (53%)
• Gaps: 226/1180 - (19%)

  Fly     8 GVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFEN 72
            ||.|.|||:.:|.|.|::||:|||.:..||||||.|.:|||||:.::||..|.:.:|:.|..:|.
Zfish    13 GVGDMVLLEPLSEESFIENLKKRFDHNEIYTYIGSVVISMNPYKSLSIYSAEKVEEYRNRNFYEL 77

  Fly    73 APHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLI 137
            :||::|:||.|||.|:.:.:|.||||:||||||||||||.:|.|:|||. .:|| |:.:||..|:
Zfish    78 SPHIYALADEAYRSLRHQDKDQCILITGESGAGKTEASKFVMSYVAAVC-GKGQ-EVNKVKEQLL 140

  Fly   138 QSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSF 202
            |||.:||.||||||.|||||||||||||||||:|.||:||:|:||||||||||:|..||||||.|
Zfish   141 QSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHIF 205

  Fly   203 YQLLRGANDNELRQYELQKETGKYHYLNQGSMDI--LTEKSDYKGTCNAFKTLGFSTDEVQTIWR 265
            ||||.||:|:.|::.:|.::..||:||:..|..:  |.:.:.::...||.:.:||..||||:|..
Zfish   206 YQLLSGASDDMLKKLKLDRDFSKYNYLSLDSATVNGLDDAASFRTVRNAMQIVGFMEDEVQSILE 270

  Fly   266 TIAAVLHLGNVEFQTIE-----DELVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVMQK 325
            .|||||.|||:||:...     ||..:.:|..||...:||.:.::.|..|.:.|.:.|....:..
Zfish   271 LIAAVLKLGNIEFKPESRVNGFDESRVKDKNDLKEMCELLGIEQSVLERAFSFRTVEAKMEKVST 335

  Fly   326 DHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDS--N 388
            ..|..||.|.:|||||.:|.|||||:::|||.:|   .::|:.| ..|:|||||||||||::  |
Zfish   336 TLNVAQAYYARDALAKNLYSRLFTWLVNRINESI---KAQTKTR-KKVMGVLDIYGFEIFENGDN 396

  Fly   389 SFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDE 453
            |||||.||||||||||:||||.|::|||||.||||||||||||||.|||||:|....||:|::||
Zfish   397 SFEQFIINYCNEKLQQIFIELTLREEQEEYIREGIEWTNIEYFNNAIICDLIENNKNGILAMLDE 461

  Fly   454 ACLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKP----TDKELKHREDFRITHYAGDVIYNINGF 514
            .||..|.|||:|.|..::...::|.|:.||..|.    ||..|.| ..|||.||||.|:|.:.||
Zfish   462 ECLRPGTVTDETFLDKLNTVCAEHQHFESRLSKNSKFLTDHSLPH-NCFRIQHYAGKVLYRVEGF 525

  Fly   515 IEKNKDTLYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEP 579
            ::||.|.||:|..:.::.:....:..::||| ...|...|||.|||..|:.|:..|:..||.|.|
Zfish   526 VDKNNDLLYRDLSQAMYKANHNLIKLLFPEG-NPAKVNLKRPPTAGFQFRASVGTLMKNLLTKNP 589

  Fly   580 FYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPN 644
            .|:|||||||.|::.:|.:..|.||||||||:||:||||||:..||.|:..|.||||:.:.|||:
Zfish   590 NYIRCIKPNDKKAAHIFTDSLVCHQVRYLGLMENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPH 654

  Fly   645 FRAGSDRDGVRVLIEEKKF-AQDVKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWI 708
            :: |..|:||.||:.:.:. |::..||.:|||||:|||||.||.:|.:.:..:..|:||..|||.
Zfish   655 WK-GPAREGVEVLLSDLQVPAEEFAYGRSKIFIRNPRTLFFLEEKRRQCLEDLAALIQKIYRGWK 718

  Fly   709 VRRNFKKMKAAITIVRAY------------------------KAYKLRSYVQELANRLRKAKQMR 749
            .|.:|..:|.:..:|.|:                        :.:|.|..::||.::.|..:.:.
Zfish   719 CRTHFLLLKKSQVVVAAWYRRFAQQKKYQKIRCSALVVQSFIRGWKARKLLRELKHKKRCEEAVT 783

  Fly   750 D-----YGKSIQWPQPPLAGRKVEA-KLHRMFDFWRANMILHKYPRSEWPQLRLQIIAATALAGR 808
            .     :|...:|   .|...|.|| ..|.:...|.|  .|....|.|..:|:.:..:..|::..
Zfish   784 TISAYWHGTQARW---ELRRLKKEAWNKHAVSVIWAA--WLGTKARRELQKLKHEACSKQAVSVI 843

  Fly   809 RPYW-------------GQARR----------WVG-----DYLANSQENSGYEAYNGSIKNI--- 842
            ...|             .:|||          |:|     :|....:.|:|.:.|:.:|:.|
Zfish   844 WACWQGTKARRELKRLKEEARRKHAIAVIWAYWLGLKVRREYRKFFRANAGKKIYDFTIQRIIQK 908

  Fly   843 ------RNHPA----------------DG------------------------------------ 849
                  :..|:                ||
Zfish   909 YYLGLKKTMPSMSPIDKSWSTCPYGFLDGTHQELRRIFHLWRCKKYRSQFTEEKKATYEEKLAAS 973

  Fly   850 ETFQ------------------------------------QVLFSSFVKKFNHFN-KQANRAFIV 877
            |.|:                                    :||.:..|.|.|..| |...|.|::
Zfish   974 ELFKDKKALYPSSVSQPFKGDYVEITKNPKYQKLNSLVEDKVLLADVVSKINRANGKGTPRIFLL 1038

  Fly   878 SDSTIHKLDGIKNKFKDMKRTIKIRELTSISVSPGRDQLIVFHSSKNKDLVFSLESEYTPLKEDR 942
            :...:...|   .|...:|.::.:.:|:|:.||...|..  |.....:....:.:.:|. |..||
Zfish  1039 TKKCLVLAD---QKTGQVKASVPLPDLSSVFVSTQNDGF--FALKLREGATSAAKGDYL-LSSDR 1097

  Fly   943 IGEVV------------------------------GIVCKKYHDLTGTELRVNVTTNISCRLDGK 977
            :.|::                              ..||.|:  :.||....|   ::||:....
Zfish  1098 LIEIITKLYCTGAASAERNQIKIDISDEFLVQFKQDKVCVKF--IQGTPKNSN---SVSCKRKNN 1157

  Fly   978 ARIITVEAAS 987
             |::.|...|
Zfish  1158 -RLLEVSVPS 1166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_001188784.1	MYSc	6..690	CDD:214580	360/695 (52%)
		MYSc_Myo1	21..677	CDD:276829	344/669 (51%)
		Myosin_TH1	801..983	CDD:283635	50/337 (15%)
myo1b	XP_005168005.1	MYSc	13..700	CDD:214580	360/695 (52%)
		MYSc_Myo1	26..687	CDD:276829	344/669 (51%)
		Myosin_TH1	969..1142	CDD:283635	28/180 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53790
OrthoDB	1	1.010	-	-		D122881at2759
OrthoFinder	1	1.000	-	-		FOG0000187
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100187
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.730