Protein Alignment Myo31DF and MYO7B

DIOPT Version :9

• Sequence 1: NP_001188784.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: XP_016859658.1
• Gene: MYO7B / 4648
• HGNCID: 7607
• Length: 2164
• Species: Homo sapiens
• Alignment Length: 877
• Identity: 295/877 - (33%)
• Similarity: 454/877 - (51%)
• Gaps: 130/877 - (14%)

  Fly     8 GVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFEN 72
            ||.|.:.|..::....:.||..|:|...||||.|.:.|::||::.:.:|..|.::.|..|.:.|.
Human    66 GVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHMGEL 130

  Fly    73 APHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLI 137
            .||:||||::.|..:|:.::|.|.:|||||||||||.:|:|::::|.::   ||:  ..::..::
Human   131 PPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS---GQH--SWIEQQVL 190

  Fly   138 QSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSF 202
            ::|.|||.||||||.|||||||||||:||.|:......|..|..:|||||||.:|.|.|||:|.|
Human   191 EANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIF 255

  Fly   203 YQLLRG--ANDNELRQYELQKETGKYHYLNQG---SMDILTEKSDYKGTCNAFKTLGFSTDEVQT 262
            |.:|.|  |.|.:|.......|   ||||..|   |.:.|.:..||....:|.|.|.||..|...
Human   256 YCMLMGVSAEDKQLLSLGTPSE---YHYLTMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWD 317

  Fly   263 IWRTIAAVLHLGNVEFQ-TIEDELVISNKQH---LKSTAKLLQVTETELSTALTKRVIAAGGNVM 323
            :.:.:||:||||||.|. ::.:.|..|:...   ..:..|||:|...||...|.|..|...|..:
Human   318 VIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFV 382

  Fly   324 QKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSN 388
            .:..|..||...:||..|.||..||.||:.:||.||....::........||:|||:|||.|::|
Human   383 TRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENN 447

  Fly   389 SFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDE 453
            ||||.|||:.||.|||.|::.|...|||||:.|.|.|..|.|.:|:...||:......||:::||
Human   448 SFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDE 512

  Fly   454 ACLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIYNINGFIEKN 518
            .    .:....|.|..:.|..|.|.: ....|:|  |.: |...|.|.|:||:|.|...||:|||
Human   513 E----SRFPQGTDLTMLQKLNSVHAN-NKAFLQP--KNI-HDARFGIAHFAGEVYYQAEGFLEKN 569

  Fly   519 KDTLYQDFKRLLHNSKDANLSEMWPEGAQDIK-------------------KTTKRPLTAGTLFQ 564
            :|.|..|...|:::||:..|.|::.....:.|                   .:.|||.|.|:.|:
Human   570 RDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFK 634

  Fly   565 RSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDK 629
            :|:..|:..|...:|:::||||||:.|...:||.|....|:||.|::|.:.:|::||..|..:::
Human   635 QSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEE 699

  Fly   630 FLLRYKMISQYTWPNFRAGSDRDGVRVLIEEK-------------KFAQDVKYGHTKIFIRSPR- 680
            |..|:.::    .||        .:|:.::.|             :..:|.|.|.||||:|..:
Human   700 FSQRFGVL----LPN--------AMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQD 752

  Fly   681 TLFALEHQRNEMIPHIVTLLQKRVRGWIVRRNF-KKMKAAITIVRAYKAY--------------K 730
            ||  ||.||::::......:||.:||:..|:.| ::.:||:|:...::.|              :
Human   753 TL--LEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFER 815

  Fly   731 LRSYV--QELANRLRKAKQ--------MRDYGKSIQWPQPPLAGRKVEAKLHRMFDFWRANMILH 785
            |::..  |.||.:.:..:|        .|.|          |..::|:||.       ||.:::.
Human   816 LQAIARSQPLARQYQAMRQRTVQLQALCRGY----------LVRQQVQAKR-------RAVVVIQ 863

  Fly   786 KYPRSEWPQLRLQIIAATALAGRRPYWGQARR 817
            .:.|              .:|.||.:  |.|:
Human   864 AHAR--------------GMAARRNF--QQRK 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_001188784.1	MYSc	6..690	CDD:214580	265/723 (37%)
		MYSc_Myo1	21..677	CDD:276829	255/696 (37%)
		Myosin_TH1	801..983	CDD:283635	5/17 (29%)
MYO7B	XP_016859658.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910