Protein Alignment Myo31DF and Myo3b

DIOPT Version :10

• Sequence 1: NP_523538.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: NP_001380706.1
• Gene: Myo3b / 366069
• RGDID: 1560313
• Length: 1333
• Species: Rattus norvegicus
• Alignment Length: 983
• Identity: 293/983 - (29%)
• Similarity: 491/983 - (49%)
• Gaps: 183/983 - (18%)

  Fly    11 DFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFENAPH 75
            |.|.|:.:..:..:..|:||:.:..||||:|::.:::||::.::||.|:..|.|.|.:...|.||
  Rat   363 DLVNLEVLDEDTIIYWLQKRYADALIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRSSNPPH 427

  Fly    76 LFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLIQSN 140
            :||.||:||:.|....:|.||:||||||:||||.:.:|::::..:..|..|.    ::..::|.|
  Rat   428 IFASADNAYQCLVTFSKDQCIVISGESGSGKTENAHLIVQHLTFLGKANNQT----LRQKILQVN 488

  Fly   141 AILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSFYQL 205
            :::|.||||:|..||||||||||:::.|......:|..|:.||||||||:||..||:|||.||.:
  Rat   489 SLVEAFGNARTAINDNSSRFGKYLEMMFTPTGAVMGARISEYLLEKSRVIQQAAGEKNFHIFYYI 553

  Fly   206 LRGA-NDNELRQYELQKETGKYHYL----NQGSMDILTEKSDYKGTC----NAFKTLGFSTDEVQ 261
            ..|. :..:|.::.|.:|... .|:    .:.:.|| |.|..|:...    :.|:.:||:..||.
  Rat   554 YAGLYHQKKLAEFRLPEEKPP-RYIAAETERVTQDI-TSKESYRRQFDVIQHCFRIIGFTDKEVH 616

  Fly   262 TIWRTIAAVLHLGNVEFQTIE-----DELVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGN 321
            :::|.:|.:|::||:||..|.     |:..:.|.:.|::.|.:|.:...||..|||...:...|.
  Rat   617 SVYRILAGILNIGNIEFAAISSQHQTDKSEVPNPEALENAASVLCINSEELQEALTSHCVVTRGE 681

  Fly   322 VMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSK----TQARFNSVIGVLDIYGF 382
            .:.:.:...:||..:||::||:|.|||:||::|||  .|.:..|    .:.|.|  :|:|||:||
  Rat   682 TIVRANTVDRAEDVRDAMSKALYGRLFSWIVNRIN--TLLQPDKNICSAEDRMN--VGILDIFGF 742

  Fly   383 EIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGI 447
            |.|..|||||.|||..||::|..|.:.|...||.||::||::...::|.:|:.:.|:..|...|:
  Rat   743 EDFQRNSFEQLCINIANEQVQFYFNQHVFALEQMEYKKEGVDAVLVQYEDNRPLLDMFLQKPLGL 807

  Fly   448 IAIMDEACLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIYNIN 512
            :|::||.. ...:.||.||:...:.||.....:     :|...||    .|.|.||||.|:|:.:
  Rat   808 LALLDEES-RFPQGTDQTLVDKFEDNLRCKFFW-----RPKGVEL----SFGIQHYAGPVLYDAS 862

  Fly   513 GFIEKNKDTLYQDFKRLLHNSKDANLSEMW----------------------------------- 542
            |.:|||:|||..|...:|..|::..|.:::
  Rat   863 GVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRARITASSRSLPPHFSAGRAKV 927

  Fly   543 --------PEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEE 599
                    ||...::|:.     |..:.|:.|:.||:..::..:|.:||||||||.:.:..|.::
  Rat   928 DTLEVIRHPEETTNMKRQ-----TMASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDRKALQFSQD 987

  Fly   600 RVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFRA----GSDRDGVRVLIEE 660
            ||..|:|..|:||.:.:||.|:.||..:::|:.||..::      |||    .::::....::|:
  Rat   988 RVLAQLRSTGILETVSIRRQGYSHRILFEEFVRRYYYLA------FRAHQTPPANKESCVAILEK 1046

  Fly   661 KKFAQDVKYGHTKIFIRSPRTLFALEHQRNEMIPHI---VTLLQKRVRGWIVRRNFKKM-----K 717
            .:....| .|.||:|::    .:.:| |.|.::..:   |.:||...:||:..|.:|:.     |
  Rat  1047 SRLDHWV-LGKTKVFLK----YYHIE-QLNLLLREVMGRVVMLQAYTKGWLGARRYKRAKEKREK 1105

  Fly   718 AAITIVRAYKAYKLRSYVQELANRLRKAKQMRDYGKSIQWPQPPLAGRKVEAKLHRMFDFWRANM 782
            :||||..|::.|..|          ||.||.|.              |:.|:..|       ...
  Rat  1106 SAITIQSAWRGYDTR----------RKFKQTRH--------------RRNESAAH-------TQA 1139

  Fly   783 ILHKYPRSEWPQLRLQIIAATALAGRRPYWGQARRWVGDYLANSQENSGYEAYNGSIKNIRNHPA 847
            :|...|..:                |.|                  :||.|:.:...:..||.||
  Rat  1140 VLQTTPDEK----------------RFP------------------DSGVESNSRHEETSRNCPA 1170

  Fly   848 DGET-----FQQVLFSSFVKKFNHFNKQANRAFIVSDSTIHKLDGIKNKFKDMKRTIKIRELTSI 907
            :.:|     .|....||.|.. .|.:|:|..|  |::.::...||..::...............:
  Rat  1171 EADTDWHPQTQSSPASSDVTS-GHADKEAGNA--VAELSVAGTDGSPSRVCHTATAHHRLSPCEV 1232

  Fly   908 SVSPGRDQ 915
            |:.||.::
  Rat  1233 SLKPGSEE 1240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_523538.1	MYSc_Myo1	21..677	CDD:276829	238/720 (33%)
		Myosin_TH1	801..977	CDD:461801	24/120 (20%)
Myo3b	NP_001380706.1	Protein Kinases, catalytic domain	20..310	CDD:473864
		MYSc_Myo3	373..1062	CDD:276830	238/720 (33%)
		IQ	1102..1124	CDD:197470	10/31 (32%)