Protein Alignment Myo31DF and Mhc

DIOPT Version :10

• Sequence 1: NP_523538.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: NP_523587.4
• Gene: Mhc / 35007
• FlyBaseID: FBgn0264695
• Length: 1962
• Species: Drosophila melanogaster
• Alignment Length: 1058
• Identity: 318/1058 - (30%)
• Similarity: 503/1058 - (47%)
• Gaps: 202/1058 - (19%)

  Fly    14 LLDQVSMEKF-----------------MDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETI 61
            ||.||:..|:                 :.|||:|:.|..||||.|..||::|||::..:|.....
  Fly    76 LLQQVNPPKYEKAEDMSNLTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCA 140

  Fly    62 RKYKGRELFENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQ 126
            :.|:|:...|..||:|||:|.||..:.....:..:||:|||||||||.:|.::.|.|.|..::..
  Fly   141 KMYRGKRRNEVPPHIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGASKKT 205

  Fly   127 NEIERVKNVL----IQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKS 187
            :|..:.|..|    :|:|.:||.||||||.||||||||||::.|.|.......|..|..|||||:
  Fly   206 DEAAKSKGSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAGADIETYLLEKA 270

  Fly   188 RVVQQQPGERNFHSFYQLLRGA----------NDNELRQYELQKETGKYHYLNQGSMDI--LTEK 240
            ||:.||..||::|.|||::.|:          .||   .|:       ||.::||.:.:  :.:.
  Fly   271 RVISQQSLERSYHIFYQIMSGSVPGVKDICLLTDN---IYD-------YHIVSQGKVTVASIDDA 325

  Fly   241 SDYKGTCNAFKTLGFSTDEVQTIWRTIAAVLHLGNVEFQT--IEDELVISNKQHLKSTAKLLQVT 303
            .::..|..||..|||:..|.:.::|..|||:|:|.::|:.  .|::.....::.....:||....
  Fly   326 EEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEEGGRVSKLFGCD 390

  Fly   304 ETELSTALTKRVIAAGGNVMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQA 368
            ..||...|.|..|..|...:.:..|..|......||.|.::||||.|::.:.|..:     .||.
  Fly   391 TAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLVKKCNETL-----DTQQ 450

  Fly   369 RFNSVIGVLDIYGFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNN 433
            :....||||||.|||||:.|.|||.|||:.||||||.|...:...|||||||||||||.|::..:
  Fly   451 KRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQEEYQREGIEWTFIDFGMD 515

  Fly   434 KIIC-DLVEQPHKGIIAIMDEACLSVGKVTDDTLLGAMDKNLSKH-----PHYTSRQLKPTDKEL 492
            ..:| ||:|:| .||::|::|..: ..|.||.|.   .:|..:.|     |....:..|| .::.
  Fly   516 LQLCIDLIEKP-MGILSILEEESM-FPKATDQTF---SEKLTNTHLGKSAPFQKPKPPKP-GQQA 574

  Fly   493 KHREDFRITHYAGDVIYNINGFIEKNK----DTLYQDFKRLLHNSKDANLSEMWPE------GAQ 547
            .|   |.|.||||.|.|||.|::||||    ||:...||:    |::..|.|::.:      |.:
  Fly   575 AH---FAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKK----SQNKLLIEIFADHAGQSGGGE 632

  Fly   548 DIK----KTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYL 608
            ..|    |......|..:.::..:..|:.||...:|.:||||.||::|...|.|...|.||:...
  Fly   633 QAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCIIPNEMKQPGVVDAHLVMHQLTCN 697

  Fly   609 GLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFRAGSDRD--GVRVLIEEKKFAQD-VKYG 670
            |:||.:|:.|.||.:|..|..|.:|||::.    |....|.::|  ...::|:.....:| .:.|
  Fly   698 GVLEGIRICRKGFPNRMMYPDFKMRYKIMC----PKLLQGVEKDKKATEIIIKFIDLPEDQYRLG 758

  Fly   671 HTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWIVRRNFKKM---KAAITIVRAYKAYKLR 732
            :||:|.|: ..|..:|..|:|.:..|::.:|...||::.|:.|||:   :.|:.:|:
  Fly   759 NTKVFFRA-GVLGQMEEFRDERLGKIMSWMQAWARGYLSRKGFKKLQEQRVALKVVQ-------- 814

  Fly   733 SYVQELANRLRKAKQMRDYGKSIQWP--------QPPLAGRKVEAKLHRMFDFWRANMILHKYP- 788
                   ..|||..|:|      .||        :|.|...::|.::.|:.:..:....||...
  Fly   815 -------RNLRKYLQLR------TWPWYKLWQKVKPLLNVSRIEDEIARLEEKAKKAEELHAAEV 866

  Fly   789 --RSEWPQLRLQIIA-----ATALAGRRPYWGQARRWVGDYLANSQENSGYEAYNGSIKN----- 841
              |.|...|..:::|     ..:|:|.:   |..:    ||   .:.|:...|....::|
  Fly   867 KVRKELEALNAKLLAEKTALLDSLSGEK---GALQ----DY---QERNAKLTAQKNDLENQLRDI 921

  Fly   842 ----IRNHPADGETFQQVLFSSFVKKFNHFNKQANRAFIVSDSTIHKLDGIKNKFKDMKRTIKIR 902
                .:...|..:.|||             .|:|::          ::.|:|...:|::..::..
  Fly   922 QERLTQEEDARNQLFQQ-------------KKKADQ----------EISGLKKDIEDLELNVQKA 963

  Fly   903 ELTSISVSPGRDQLIVFHSSKN--------KDLVFSLESEYTPLKE--DRIGEVVGIVCKKYHDL 957
            |         :|:....|..:|        .:|:..|..|.....|  .:.||          :|
  Fly   964 E---------QDKATKDHQIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGE----------EL 1009

  Fly   958 TGTELRVNVTTNISCRLD 975
            ...|.::|....:..:|:
  Fly  1010 QAAEDKINHLNKVKAKLE 1027

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_523538.1	MYSc_Myo1	21..677	CDD:276829	251/713 (35%)
		Myosin_TH1	801..977	CDD:461801	32/199 (16%)
Mhc	NP_523587.4	Myosin_N	33..75	CDD:460670
		MYSc_Myh1_insects_crustaceans	100..765	CDD:276874	250/696 (36%)
		Myosin_tail_1	842..1922	CDD:460256	39/238 (16%)