Protein Alignment Myo31DF and Myo5b

DIOPT Version :10

• Sequence 1: NP_523538.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: XP_008770307.1
• Gene: Myo5b / 25132
• RGDID: 621347
• Length: 1854
• Species: Rattus norvegicus
• Alignment Length: 1051
• Identity: 318/1051 - (30%)
• Similarity: 495/1051 - (47%)
• Gaps: 193/1051 - (18%)

  Fly     8 GVQDFVLLDQVSMEKFMDNLRKRF-QNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFE 71
            |..|...|..:.....:.||:.|| ::..||||.|.|.|::|||.|:.|||.:.|..|.|:.:.:
  Rat    78 GENDLTALSHLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYAYSGQNMGD 142

  Fly    72 NAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVL 136
            ..||:||:|:.||:.:.:.:::..|::|||||||||.::|..|:|.|.|..:.....||   ..:
  Rat   143 MDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASDTNIE---EKV 204

  Fly   137 IQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHS 201
            :.|:.|:|..|||||.|||||||||||::|.||.|...:|..:..|||||||||.|...|||:|.
  Rat   205 LASSPIMEAIGNAKTTRNDNSSRFGKYIEIGFDKKYHIIGANMRTYLLEKSRVVFQADDERNYHI 269

  Fly   202 FYQLLRGANDNELRQYELQKETGKYHYLNQGSMDI--LTEKSDYKGTCNAFKTLGFSTDEVQTIW 264
            ||||...|:..|.::..|......::..:.|:..|  :.:..|::.|..|...||.......:|:
  Rat   270 FYQLCAAASLPEFKELALTCAEDFFYTAHGGNTTIEGVDDAEDFEKTRQALTLLGVRESHQISIF 334

  Fly   265 RTIAAVLHLGNVEFQTIEDE---LVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVMQKD 326
            :.||::||||:||.|...|.   .:....:||.:..:||.:..:::...|..|.:........|.
  Rat   335 KIIASILHLGSVEIQAERDGDSCSISPQDEHLSNFCRLLGIEHSQMEHWLCHRKLVTTSETYVKT 399

  Fly   327 HNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSNSFE 391
            .:..|....::||||.||.:||:||:..||:|:     :|..:.:|.||||||||||.|:.||||
  Rat   400 MSLQQVVNARNALAKHIYAQLFSWIVEHINKAL-----QTSLKQHSFIGVLDIYGFETFEINSFE 459

  Fly   392 QFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDEACL 456
            ||||||.||||||.|...|.|.|||||.:|.|.||.|::::|:...||:| ...||:.::||.|
  Rat   460 QFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIE-AKLGILDLLDEEC- 522

  Fly   457 SVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIYNINGFIEKNKDT 521
            .|.|.||......:.:..|...|:...::..|        .|.:.|:|..|.|..:||:|||:||
  Rat   523 KVPKGTDQNWAQKLYERHSNSQHFQKPRMSNT--------AFIVIHFADKVEYLSDGFLEKNRDT 579

  Fly   522 LYQDFKRLLHNSKDANLSEMWPEGAQDIKKT--------------TKRPL----------TAGTL 562
            :|::...:|..||...:::::.:....:..|              :.|||          :.|..
  Rat   580 VYEEQINILKASKFPLVADLFRDDKDSVPATNTAKSRSSSKINVRSSRPLMKAPNKEHKKSVGYQ 644

  Fly   563 FQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRY 627
            |:.|:..|:.||....|.|||||||||.|....||.:|...|:|..|:||.:|:..||:..|..|
  Rat   645 FRTSLNLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWTY 709

  Fly   628 DKFLLRYKMISQYTWPNFRAGSDRDGV--RVLIEEKKFAQDVKYGHTKIFIRSPRTLFALEHQRN 690
            ..|..||:::.:..  .....:|:..:  .||....|.....::|.||||.|:.:..: ||..|.
  Rat   710 HDFFNRYRVLMKKR--ELANTTDKKNICKSVLESLIKDPDKFQFGRTKIFFRAGQVAY-LEKLRA 771

  Fly   691 EMIPHIVTLLQKRVRGWIVRRNFKKMKAA-ITIVRAYKAYKLRSYVQELANRLRKA----KQMRD 750
            :.......::||.||||:.|..:::::|| :|:.|..:.|..|...:.| .|.|.|    ||.|
  Rat   772 DKFREATIMIQKTVRGWLQRVKYRRLRAATLTLQRFCRGYLARRLTEHL-RRTRAAIVFQKQYR- 834

  Fly   751 YGKSIQWPQPPLAGRKVEAKLHRMFDFWRANMILHKYPRSEWPQLRLQIIAATALAGRRPYWGQA 815
                      .|..|:...::.      ||.:|:..|.|              |:..||.|
  Rat   835 ----------MLKARRAYCRVR------RAAVIIQSYTR--------------AMCVRRSY---- 865

  Fly   816 RRWVGDYLANSQENSGYEAYNGSIKNIRNHPADGETFQQVLF---SSFVKKF-------NHFNKQ 870
                                                 :|||.   ::.::|:       .||.:|
  Rat   866 -------------------------------------RQVLTEHKATIIQKYARGWMARRHFQRQ 893

  Fly   871 ANRAFIV---------------------SDSTIHKLD-GIKNKFKDMKRTI------------KI 901
            .:.|.::                     |...:.:|: |::||...::|.|            ::
  Rat   894 RDAAIVIQCAFRRLKARQALKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSEQL 958

  Fly   902 RELTS---ISVSPGRDQLIVFHSSKNKDLVFSLESEYTPLK--------EDRIGEVVGIVCKKYH 955
            ..:||   :.|...:.:|..:..::..|....|:.|...|:        |.|       |.:..|
  Rat   959 SAVTSTHAMEVEKLKKELARYQQNQEADPSLQLQEEVQSLRTELQKAHSERR-------VLEDTH 1016

  Fly   956 DLTGTELRVNV 966
            :....|||..|
  Rat  1017 NRENGELRKRV 1027

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_523538.1	MYSc_Myo1	21..677	CDD:276829	249/687 (36%)
		Myosin_TH1	801..977	CDD:461801	35/221 (16%)
Myo5b	XP_008770307.1	MYSc_Myo5	91..759	CDD:276831	249/687 (36%)
		IQ	773..795	CDD:197470	7/21 (33%)
		IQ	821..842	CDD:197470	8/31 (26%)
		IQ	871..891	CDD:197470	2/19 (11%)
		SMC_prok_B	906..>1268	CDD:274008	23/129 (18%)
		Myo5b_CBD	1480..1851	CDD:271261