Protein Alignment Myo31DF and myo-6

DIOPT Version :9

• Sequence 1: NP_001188784.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: NP_001022590.1
• Gene: myo-6 / 176764
• WormBaseID: WBGene00009730
• Length: 1235
• Species: Caenorhabditis elegans
• Alignment Length: 1109
• Identity: 317/1109 - (28%)
• Similarity: 508/1109 - (45%)
• Gaps: 209/1109 - (18%)

  Fly     4 QREAGVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRE 68
            ::...:.:...|::.|:   :.|||:|:.:..||||.|..||.:|||:.:.||.......|..:.
 Worm    85 EKTEDMSNLTFLNEASV---LHNLRQRYYSMMIYTYSGLFCVFINPYKMLPIYTDSVASMYVNKR 146

  Fly    69 LFENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAV-TNAQGQNEIERV 132
            ..|..|||||::|.|:|.:...:::..:||:|||||||||.:|.::.|.|.: :..:.|.....:
 Worm   147 RAEMPPHLFAVSDEAFRNMMSDKENQSMLITGESGAGKTENTKKVIAYFAMIGSGNKDQKSESSL 211

  Fly   133 KNVLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGER 197
            :|.::|:|..:|.|||..|.||.||||:||::.|.||.|...|||.|.:||||||||::|.||||
 Worm   212 ENQVVQANPAIEAFGNGATTRNYNSSRYGKFIRIHFDRKGKLVGGDIEHYLLEKSRVIKQAPGER 276

  Fly   198 NFHSFYQLLRGANDNELRQ-YELQKETGKYHYLNQGSMDI--LTEKSDYKGTCNAFKTLGFSTDE 259
            ::|.|||::   ....||: |.|......|.:::|..:.:  :.:..:::.|..||..:|||..|
 Worm   277 SYHIFYQIM---TQKALRERYGLSDNIRDYKFVSQAEITVPGMNDTEEWQITDGAFNVMGFSERE 338

  Fly   260 VQTIWRTIAAVLHLGNVEF-QTIEDELV-ISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNV 322
            ...:::..:|::|:||..| |...||.. :.:.....:..||..:...:...|||:..|..|...
 Worm   339 KDDLYKLCSAIMHIGNSTFKQKPRDEQAEVDDMTSPTAACKLFGINTDQFLNALTRPRIKVGMEW 403

  Fly   323 MQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSV---IGVLDIYGFEI 384
            :.|..|..|.::...||:||||.|:|.|:|.|:|:.:       ||..:.:   ||||||.||||
 Worm   404 VNKGQNVQQVDWAVGALSKAIYARMFNWLIKRVNKTL-------QANSDEMVYYIGVLDIAGFEI 461

  Fly   385 FDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIIC-DLVEQPHKGII 448
            ||.|||||..||:.||||||.|...:...|||||||||||||.|::..:...| :|:|:| .||:
 Worm   462 FDRNSFEQLWINFVNEKLQQFFNHHMFVLEQEEYQREGIEWTFIDFGLDLQSCIELIEKP-LGIV 525

  Fly   449 AIMDEACLSVGKVTDDTLLG-AMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIYNIN 512
            :::||.|: |.|.:|.|.:. .:.::|.|||::  ::.|| .|..:....|.|.||||.|.||..
 Worm   526 SMLDEECI-VPKASDMTYVDKLLTQHLGKHPNF--QKAKP-PKGKQAEAHFSIMHYAGTVRYNAE 586

  Fly   513 GFIEKNKDTLYQDFKRLLHNS-KDANLSEMWPEGAQDI-------------KKTTKRP--LTAGT 561
            .:::||||.|......:|..| |:..|.::|.|...|:             ||..|..  ||..|
 Worm   587 QWLDKNKDPLNDSAVAILKTSDKEGVLYQLWEEYQTDVDREESEKRGKAQAKKKGKSASFLTVST 651

  Fly   562 LFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQR 626
            :::.|:..|:..|....|.::|||.||:.|:|.:.|...|.:|:...|:||.:|:.|.||.:|..
 Worm   652 MYRESLTSLMTMLHTTHPHFIRCIIPNEKKTSGLIDAPLVLNQLTCNGVLEGIRICRKGFPNRMM 716

  Fly   627 YDKFLLRYKMISQYTWPNFRAGSDRDG-------VRVLIEEKKFAQDV-KYGHTKIFIRSPRTLF 683
            :..|..||.:::.      ...||:|.       :|.|.:..:...|. |.|.||:|.|: ..|.
 Worm   717 FADFRFRYAILAA------DEASDKDAAKASKAMLRKLSKNNQLNVDTFKVGTTKVFFRA-GMLA 774

  Fly   684 ALEHQRNEMIPHIV--------------------------TLLQKRVRGWIVRRN------FKKM 716
            .||..|:|.:..::                          .::|:.:|.||..|:      |.::
 Worm   775 RLEELRDEALSAVILKFQCSLRHYLAQLEYKRRLDREDAYPIIQENIRAWIKLRSWPWYRLFSRL 839

  Fly   717 KAAITIVRAYKAYKLRSYVQELANRLRKAKQMRDYGKSIQWPQPPLAGRKVEAKLHRMFDFWRAN 781
            |..:      |..|..:.::.|.   :|.|::.:..|     :...|.:|...:|....|.:...
 Worm   840 KPML------KGMKSNAEIEALE---KKCKELEENHK-----REEEARKKYADELRAKIDQYEET 890

  Fly   782 MILHKYPR-------------------------------SEWPQLRLQIIAATALAGRRPYWGQA 815
            ...|:..|                               ||..:||.:         .:..|.:.
 Worm   891 KAAHERDRMLLDKRNKEIEELNRNLKAESESNYENAKKASELERLREK---------EKKEWDEK 946

  Fly   816 RRWVGDYLAN--SQENSGYEAYNGSIKNIRNHPADGETF------QQVLFSSFVKKFNHFNKQAN 872
            .|.:.....|  :|..:..|.....|..::   .|.|..      |:.:.:..|.:...|.::|.
 Worm   947 ERRMQMEAENEANQHKTQTEKLKDQISTLQ---TDFEKVSAQRKAQEQMNAELVDEVASFKQKAE 1008

  Fly   873 RAFIVSDSTIHKLDGIKNKFKDMKRTIKIRELTSISVSPGRDQLIVFHSSKNKDLVFSLESEYTP 937
            ||.......:..||.:.:|....||...                  .|...||.|...|::..|.
 Worm  1009 RAEEQKKKLVEDLDSLDDKLAAEKRANN------------------EHVKHNKKLEGQLKATQTQ 1055

  Fly   938 L----------------KEDRIGEVVGIVCKKYHDLTGTELRVNVTTNISCRLDGKARIITVEAA 986
            |                :|..|||:              :|:.....|:..:|....|    :..
 Worm  1056 LTLALKEKHEFDVDCKRRESEIGEL--------------KLKAQGDANLISKLQAMLR----KCI 1102

  Fly   987 SNVE 990
            |.:|
 Worm  1103 SRIE 1106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_001188784.1	MYSc	6..690	CDD:214580	256/718 (36%)
		MYSc_Myo1	21..677	CDD:276829	250/690 (36%)
		Myosin_TH1	801..983	CDD:283635	34/205 (17%)
myo-6	NP_001022590.1	Myosin_N	34..72	CDD:367160
		MYSc_class_II	99..769	CDD:276951	251/693 (36%)
		SbcC	<774..1178	CDD:223496	63/395 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910