Protein Alignment Myo31DF and hum-5

DIOPT Version :9

• Sequence 1: NP_001188784.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: NP_497809.1
• Gene: hum-5 / 175521
• WormBaseID: WBGene00002038
• Length: 1017
• Species: Caenorhabditis elegans
• Alignment Length: 1010
• Identity: 515/1010 - (50%)
• Similarity: 692/1010 - (68%)
• Gaps: 35/1010 - (3%)

  Fly     8 GVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFEN 72
            ||:|.|||..:.::..:.||:.|||.|.||||||||.|::|||||:.||...|:.:|||||::|.
 Worm    12 GVEDLVLLSTIDLKSVVQNLQLRFQKGRIYTYIGEVLVAVNPYRQLGIYEKSTVDQYKGREIYER 76

  Fly    73 APHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLI 137
            |||:|||||:|||.:|:..:|:||:|||||||||||.|||||||:||:||.:.|.|||||||||:
 Worm    77 APHVFAIADAAYRSMKRFGRDSCIVISGESGAGKTETSKIIMKYLAAITNVRQQGEIERVKNVLL 141

  Fly   138 QSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSF 202
            :||.|||.||.|||.||||||||||||.|.|||..|||||.|:||||||||||:||.||||||.|
 Worm   142 RSNCILEAFGCAKTTRNDNSSRFGKYMHINFDYDGDPVGGNISNYLLEKSRVVRQQEGERNFHVF 206

  Fly   203 YQLLRGANDNELRQYELQKETGKYHYLNQG---SMDILTEKSDYKGTCNAFKTL-GFSTDEVQTI 263
            |||:.|.:|..|||:.|.|:..:|::||||   .:..:.:..|:.....|.::: .|...:|:::
 Worm   207 YQLVNGGDDGLLRQFGLTKDAKQYYFLNQGQSHKVASINDSRDFAEVQTALRSIHTFDKQDVESM 271

  Fly   264 WRTIAAVLHLGNVEFQTIEDE-----LVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVM 323
            |..||.::|||||.|  |:.|     :.|:.|..|::.|:.|.||..||:.:|:.:|:||.|:::
 Worm   272 WSVIAGLIHLGNVRF--IDGENSSGAVHIAEKAALQNAARCLNVTPDELAKSLSSQVVAAHGDIV 334

  Fly   324 QKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSN 388
            :|.|:...|.|.:||||||:|:|||:|::|::|.||..:.|...:: :.|||||||||||||.:|
 Worm   335 KKQHDVNAAYYTRDALAKALYERLFSWMVSKVNEAISVQNSSRYSK-SHVIGVLDIYGFEIFGTN 398

  Fly   389 SFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDE 453
            ||||.|||||||||||||||||||||||||:||||:|..|||||||:||||||.|..||::|:||
 Worm   399 SFEQLCINYCNEKLQQLFIELVLKQEQEEYEREGIKWVKIEYFNNKVICDLVEIPRTGILSILDE 463

  Fly   454 ACLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIYNINGFIEKN 518
            ||.|:|.|||...||.:||.|..|.|||||.||.:||.:.. |:|:||||||||.|::.||::||
 Worm   464 ACASIGNVTDKVFLGELDKKLKSHKHYTSRNLKQSDKSMGF-EEFKITHYAGDVTYSVMGFMDKN 527

  Fly   519 KDTLYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVR 583
            ||||:||.||||::||:..:..::|:|::.:.:..:||.|||.||:.||::||..|.:|||.|:|
 Worm   528 KDTLFQDLKRLLYHSKNRLVKSLFPDGSKSMAEVNRRPPTAGFLFKNSMSELVKQLAQKEPHYIR 592

  Fly   584 CIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFRAG 648
            |||||:.|:|.|||.|||||||||||||||:|||||||.||..||:|:.|||:|...||||.|.|
 Worm   593 CIKPNEEKNSNVFDLERVEHQVRYLGLLENVRVRRAGFAHRMPYDRFVNRYKLICASTWPNPRRG 657

  Fly   649 SD-RDGVRVLIEEKKFAQDVKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWIVRRN 712
            .. :|....::|....|||...|.||||||||:|:|.||..|.|.:|:::|.|||.|||...|..
 Worm   658 QQLKDSCMQILESAGLAQDCVQGRTKIFIRSPQTVFRLEELRTEQLPNVITFLQKMVRGVQQRER 722

  Fly   713 FKKMKAAITIVRAYKAYKLRSYVQELANRLRKAKQMRDYGKSIQWPQPPLAGRKVEAKLHRMFDF 777
            :::|.|...|:.||:.|||:||:.:|.|..|..::|||.||||:||.|||...:..::|..|...
 Worm   723 YRRMLAVRKIIGAYRRYKLKSYIWQLINAFRDVRRMRDLGKSIRWPAPPLVLAQFVSRLRVMHQR 787

  Fly   778 WRANMILHKYP---RSEWPQLRLQIIAATALAGRRPYWGQARRWVGDYLANSQE---NSGYEAYN 836
            |||..||.:.|   |:..||   :|.|...|..::..||..|.|.||||:..:|   .:....|:
 Worm   788 WRAATILARMPPHLRASLPQ---KIAAFEVLNNKKENWGYTRMWRGDYLSQQEELELPTTVSTYH 849

  Fly   837 GSIKNIR-NHPADGETFQQVLFSSFVKKFNHFNKQANRAFIVSDSTIHKLDGIKNKFKDMKRTIK 900
            ..|:.:| :||     |.:||||::|:|||.|||.:.|..||:|..:.||:  ..|||.:|..|.
 Worm   850 DGIQALRQSHP-----FGKVLFSTYVQKFNKFNKSSLRVLIVTDRFVAKLE--NKKFKLLKEPIP 907

  Fly   901 IRELTSISVSPGRDQLIVFHSSKNKDLVFSLESEYTPLKEDRIGEVVGIVCKKYHDLTGTELRVN 965
            ::.::.|||....:.|.|.|...| |:|...::   ...|:|:||::|.:...|..:|.....|.
 Worm   908 LQSISRISVCAESNGLFVIHVGDN-DIVGCAKN---TKNEERVGEMIGTLLAHYDKITMRRSPVL 968

  Fly   966 VTTNISCRLDGKARIITVEAASNVEVPNFRPKEGN 1000
            :.:.:.|.|.||.|.|.|..|.|..||....|.||
 Worm   969 IQSAVVCTLGGKTRTIRVFDAENNNVPPVFKKNGN 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_001188784.1	MYSc	6..690	CDD:214580	397/691 (57%)
		MYSc_Myo1	21..677	CDD:276829	383/665 (58%)
		Myosin_TH1	801..983	CDD:283635	62/185 (34%)
hum-5	NP_497809.1	MYSc	6..699	CDD:214580	397/690 (58%)
		MYSc_Myo1	26..687	CDD:276829	383/664 (58%)
		Myosin_TH1	808..986	CDD:283635	63/188 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157624
Domainoid	1	1.000	779	1.000	Domainoid score	I30
eggNOG	1	0.900	-	-		E2759_KOG0164
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H45576
Inparanoid	1	1.050	974	1.000	Inparanoid score	I150
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53790
OrthoDB	1	1.010	-	-		D122881at2759
OrthoFinder	1	1.000	-	-		FOG0000187
OrthoInspector	1	1.000	-	-		oto19576
orthoMCL	1	0.900	-	-		OOG6_100187
Panther	1	1.100	-	-	LDO	PTHR13140
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2201
SonicParanoid	1	1.000	-	-		X2270
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800