Protein Alignment Myo31DF and nmy-2

DIOPT Version :10

• Sequence 1: NP_523538.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: NP_492186.3
• Gene: nmy-2 / 172562
• WormBaseID: WBGene00003777
• Length: 2003
• Species: Caenorhabditis elegans
• Alignment Length: 825
• Identity: 272/825 - (32%)
• Similarity: 436/825 - (52%)
• Gaps: 98/825 - (11%)

  Fly    10 QDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFENAP 74
            :|..:|..::....:.||::|:.:...|||.|..||.:|||:::.||......::|.::..|..|
 Worm    89 EDMSMLTCLNEASVLHNLKQRYFSNLYYTYSGLFCVVINPYKRIPIYTDTIAEQFKCKKRKEMPP 153

  Fly    75 HLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQ-------------GQ 126
            |:||:||.|||.:.|.:.|..||.:|||||||||.:|.:::|:|.|.|..             ..
 Worm   154 HIFAVADEAYRSMLQERDDQSILCTGESGAGKTENTKKVIQYLAYVANRSMVKNRKTSVDLDTST 218

  Fly   127 NEI-ERVKNVLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVV 190
            |.| .:::..|:|:|.|||.|||:||.:|||||||||::.:.||......|..|..||||||||:
 Worm   219 NRIMGQLEEQLLQANPILEAFGNSKTVKNDNSSRFGKFIRVHFDSTGCISGANIEFYLLEKSRVL 283

  Fly   191 QQQPGERNFHSFYQLLRGANDNELRQYELQKETGKYHYLNQGSMDI--LTEKSDYKGTCNAFKTL 253
            :|.|.||:||.|||||:|.:..:...|.|:....||.:::.|...:  :.:.::.|.|.||...:
 Worm   284 KQAPNERSFHIFYQLLKGLSKVQREHYLLEDSLSKYKFVSNGDSKLAGVDDGAEMKETLNAMSIM 348

  Fly   254 GFSTDEVQTIWRTIAAVLHLGNVEF---QTIEDELVISNKQHLKSTAKLLQVTETELSTALTKRV 315
            |.:.:|:..|.|.::||:..||:||   ....|:.|:.|....:..|.||.|..|||..|..|..
 Worm   349 GLNDEEIGGILRVVSAVMLFGNLEFSHENKNNDQAVLLNDAVAQKIASLLGVNVTELMRAFLKPK 413

  Fly   316 IAAGGNVMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIY 380
            |....:::.:..:..|..:...|:|||.|:|||.|::.|:|:::    .:|:.:..|.||:|||.
 Worm   414 IKVQRDLVHRAQSVDQVNFSVGAIAKASYERLFRWLVHRLNKSL----DRTRQQSVSFIGILDIA 474

  Fly   381 GFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEY-FNNKIICDLVEQPH 444
            |||||::|||||.||||.||||||||...:..:||:||..||:||..::: .|.:...||:::|
 Worm   475 GFEIFETNSFEQLCINYTNEKLQQLFNNTMFVREQQEYLDEGLEWKFLDFGLNLQPTIDLIDKP- 538

  Fly   445 KGIIAIMDEACLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIY 509
            .||::.:|:.|| ..:..|.:.:..::...|:||.|..       .|::.|.||.:.||||.|.|
 Worm   539 MGIMSTLDDVCL-FPQGNDQSFVQRLNNTHSQHPKYVV-------PEIRSRSDFAVVHYAGRVDY 595

  Fly   510 NINGFIEKNKDTLYQDFKRLLHNSKDANLSEMWPE-------------------GAQDIKKTTKR 555
            ...|:..||.|.|.::...:|..||::.:.:||.:                   |::..||...|
 Worm   596 QSEGWRVKNMDPLNENVIDVLKTSKESLIVDMWKDIADVCSLSAADSTSDTGVFGSRVPKKGMFR 660

  Fly   556 PLTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAG 620
              |...|::..:|.|:.||....|.:||||.||..|...|.:...|..|:|..|:||.:|:.|.|
 Worm   661 --TVSQLYKEQLARLMSTLNNTNPHFVRCIIPNHEKKHGVLNAHLVLDQLRCNGVLEGIRICRQG 723

  Fly   621 FVHRQRYDKFLLRY-KMISQYTWPNFRAGSDRDGVRVLIEEKKF----AQDVKYGHTKIFIRSPR 680
            |..|..:.:|..|| |:::    |:.......||...:....::    |...:.|.:|||.|| .
 Worm   724 FPTRLPFQEFRQRYEKLLA----PDVNPAGFMDGKNAVYRIVQYLEVDANLFRIGQSKIFFRS-G 783

  Fly   681 TLFALEHQRNEMIPHIVTLLQKRVRGWIVRR---NFKKMKAAITI----------VRAYKAYKLR 732
            .:...|..|::.:..::...|.:.|||:.||   ..::.:.||.|          :|.::.::|.
 Worm   784 VIAEFEEMRDQKLSALIESFQAQCRGWLGRRVMVRRREQEVAIKILQRNGLAWMRLREWQWWRLL 848

  Fly   733 SYV-----------------QEL---ANRLRKAKQ-MRDYGKSIQ 756
            :.|                 |||   |.:||:::. :.||.:.::
 Worm   849 TKVKPLLEVTNKDELIAEREQELKVTAEKLRRSEVFISDYKQQME 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_523538.1	MYSc_Myo1	21..677	CDD:276829	246/699 (35%)
		Myosin_TH1	801..977	CDD:461801
nmy-2	NP_492186.3	MYSc_class_II	100..781	CDD:276951	246/699 (35%)
		Myosin_tail_1	858..1934	CDD:460256	8/36 (22%)