Protein Alignment Myo31DF and myo-1

DIOPT Version :9

• Sequence 1: NP_001188784.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: NP_492053.1
• Gene: myo-1 / 172471
• WormBaseID: WBGene00002348
• Length: 1938
• Species: Caenorhabditis elegans
• Alignment Length: 1111
• Identity: 314/1111 - (28%)
• Similarity: 514/1111 - (46%)
• Gaps: 180/1111 - (16%)

  Fly     7 AGVQDFVL----LDQVSMEKF-----------------MDNLRKRFQNGSIYTYIGEVCVSMNPY 50
            ||.:|..|    :.:|:..||                 :.|||.|:....||||.|..||.:|||
 Worm    63 AGGKDVTLKKDIVQEVNPPKFEKTEDMSNLTFLNDASVLWNLRSRYAAMLIYTYSGLFCVVINPY 127

  Fly    51 RQMNIYGPETIRKYKGRELFENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMK 115
            :::.||.....|.:.|:...|..|||||::|.|||.:.|..::..:||:|||||||||.:|.::.
 Worm   128 KRLPIYTDSVARMFMGKRRTEMPPHLFAVSDQAYRYMLQDHENQSMLITGESGAGKTENTKKVIC 192

  Fly   116 YIAAVTNAQ------GQNEIERVKNVLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADP 174
            |.|.|..:|      |:.|: .:::.::|:|.:||.||||||.||:|||||||::.|.|:.....
 Worm   193 YFATVGASQKAALKEGEKEV-TLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHFNKHGTL 256

  Fly   175 VGGIITNYLLEKSRVVQQQPGERNFHSFYQLLRGANDNELRQYELQKETGKYHYLNQGSM--DIL 237
            ....|.:||||||||::|.||||.:|.|||:..........:..|......|.::.|..:  |.:
 Worm   257 ASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFKPQLRDELLLNHPISNYWFVAQAELLIDGI 321

  Fly   238 TEKSDYKGTCNAFKTLGFSTDEVQTIWRTIAAVLHLGNVEF--QTIEDELVISNKQHLKSTAKLL 300
            .:..:::.|..||..|.||..|....:|.::|.:|:||::|  :..|::.....:...:....:.
 Worm   322 DDTEEFQLTDEAFDVLKFSPTEKMDCYRLMSAHMHMGNMKFKQRPREEQAEPDGQDEAERACNMY 386

  Fly   301 QVTETELSTALTKRVIAAGGNVMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSK 365
            .:...:...||....:..|...:.|..|..|..:...|:||.:|.|:|.|::.:.|..:..:|..
 Worm   387 GIDVDQFLKALVSPRVKVGTEWVSKGQNVDQVHWAIGAMAKGLYARVFHWLVKKCNLTLDQKGID 451

  Fly   366 TQARFNSVIGVLDIYGFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEY 430
            .    :..||||||.||||||.|||||..||:.||||||.|...:...|||||.||||:||.|::
 Worm   452 R----DYFIGVLDIAGFEIFDFNSFEQLWINFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDF 512

  Fly   431 FNNKIIC-DLVEQPHKGIIAIMDEACLSVGKVTDDTLLGAM-DKNLSKHPHYTSRQLKPTDKELK 493
            ..:...| :|:|:| .|||:::||.|: |.|.||.||...: |::|.|||::.    ||...:.|
 Worm   513 GLDLQACIELIEKP-LGIISMLDEECI-VPKATDMTLAQKLTDQHLGKHPNFE----KPKPPKGK 571

  Fly   494 HRE-DFRITHYAGDVIYNINGFIEKNKDTLYQDFKRLLHNSKDAN-LSEMW------PEGAQDIK 550
            ..| .|.:.||||.|.||:..::|||||.|......::..||..: |.|:|      .|.|...|
 Worm   572 QGEAHFAMRHYAGTVRYNVLNWLEKNKDPLNDTVVSVMKASKKNDLLVEIWQDYTTQEEAAAAAK 636

  Fly   551 KTTKRP-------LTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYL 608
            ....|.       :|...:::.|:..|:..|.|..|.::|||.||:.|.|.:.|...|.:|:...
 Worm   637 AGGGRKGGKSGSFMTVSMMYRESLNKLMTMLHKTHPHFIRCIIPNEKKQSGMIDAALVLNQLTCN 701

  Fly   609 GLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFRAGSDRDG-------VRVLIEEKKF-AQ 665
            |:||.:|:.|.||.:|.::..|:.||.:::..     .|.|..|.       ::.||.:|:. .:
 Worm   702 GVLEGIRICRKGFPNRTQHPDFVQRYAILAAK-----EAKSSDDMKTCAGAILQALINQKQLNDE 761

  Fly   666 DVKYGHTKIFIRSPRTLFALEHQRNEMIPHIVT--------------------------LLQKRV 704
            ..:.||||:|.:: ..:..:|..|::.:..|:|                          :||:.:
 Worm   762 QFRIGHTKVFFKA-GVVAHIEDLRDDKLNQIITGFQSAIRWYTATADAGARRKQLNSYIILQRNI 825

  Fly   705 RGWIVRRN------FKKMKAAITIVRAYKAYKLRSYVQELANRLRKAKQMRDYGKSIQWPQPPLA 763
            |.|.|.|.      |.|::..:         |.....:|:.....:.|.:....|..:      :
 Worm   826 RSWCVLRTWDWFLLFGKLRPQL---------KCGKMAEEMIKMAEEQKVLEAEAKKAE------S 875

  Fly   764 GRKVEAKLHRMFDFWRANMILHKYPRSEWPQLRLQIIAATALAGRRPYWGQARRWVGDYLANSQE 828
            .||.:.:.:......|:.::         ..|.|....:.|:..:......||:.|...|.::.:
 Worm   876 ARKSQEEAYAKLSAERSKLL---------EALELTQGGSAAIEEKLTRLNSARQEVEKSLNDAND 931

  Fly   829 N-SGYEAYNGSI-KNIRNHPADGETFQ---QVLFSSFVKKFNHFNKQANRAFIV------SDSTI 882
            . |.:|..|..: |..|....:.|..:   :.:..:..|.......:.|:...:      .|.||
 Worm   932 RLSEHEEKNADLEKQRRKAQQEVENLKKSIEAVDGNLAKSLEEKAAKENQIHSLQDEMNSQDETI 996

  Fly   883 HKLDGIKNKFKDMKRTI-------------------KIRE-LTSISVSPGRDQLIVFHSSKNKDL 927
            .|::..|...::..|.:                   |:.: |..:..:..|::.|...:.|:|..
 Worm   997 GKINKEKKLLEENNRQLVDDLQAEEAKQAQANRLRGKLEQTLDEMEEAVEREKRIRAETEKSKRK 1061

  Fly   928 VFSLESEYTPLK--EDRIGEVVGI-------VCKKYHDLTGTELRVNVTTNISCRL-----DGKA 978
            |   |.|   ||  ::.|.|:..|       :.||..|:....:|:.....::.||     :...
 Worm  1062 V---EGE---LKGAQETIDELSAIKLETDASLKKKEADIHALGVRIEDEQALANRLTRQSKENAQ 1120

  Fly   979 RIITVE 984
            |||.:|
 Worm  1121 RIIEIE 1126

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_001188784.1	MYSc	6..690	CDD:214580	251/738 (34%)
		MYSc_Myo1	21..677	CDD:276829	245/707 (35%)
		Myosin_TH1	801..983	CDD:283635	42/226 (19%)
myo-1	NP_492053.1	Myosin_N	33..71	CDD:280832	3/7 (43%)
		Myosin_head	86..773	CDD:278492	243/702 (35%)
		MYSc_class_II	98..773	CDD:276951	243/690 (35%)
		Myosin_tail_1	854..1918	CDD:279860	51/294 (17%)
		P-loop_NTPase	<863..>1071	CDD:304359	37/228 (16%)
		DUF2213	<1074..1224	CDD:303028	12/53 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910