Protein Alignment Myo31DF and Mhc

DIOPT Version :10

• Sequence 1: NP_523538.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: XP_061510840.1
• Gene: Mhc / 1279567
• VectorBaseID: AGAMI1_010506
• Length: 1964
• Species: Anopheles gambiae
• Alignment Length: 1027
• Identity: 317/1027 - (30%)
• Similarity: 501/1027 - (48%)
• Gaps: 155/1027 - (15%)

  Fly    10 QDFV--LLDQVSMEKF-----------------MDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNI 55
            :||.  |:.||:..|:                 :.|||:|:....||||.|..||.:|||::..:
Mosquito    71 KDFKKDLVSQVNPPKYEKCEDMSNLTYLNDASVLHNLRQRYYAKLIYTYSGLFCVVINPYKRYPL 135

  Fly    56 YGPETIRKYKGRELFENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAV 120
            |.....:.|:|:...|..|||||::|.||..:....::..:||:|||||||||.:|.::.|.|.:
Mosquito   136 YTNRCAKMYRGKRRNEVPPHLFAVSDGAYVNMLTNHENQSMLITGESGAGKTENTKKVIAYFATI 200

  Fly   121 -------TNAQGQNEIERVKNVLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGI 178
                   .||:.:..:|   :.::|:|.:||.||||||.||||||||||::.|.|.......|..
Mosquito   201 GASGKKDENAEKKGSLE---DQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFTGSGKLAGAD 262

  Fly   179 ITNYLLEKSRVVQQQPGERNFHSFYQLLRGANDNELRQYELQKETGKYHYLNQGSMDI--LTEKS 241
            |..|||||:||:.||..||::|.|||::.|:.........|..:...|:.::||.:.|  :.:..
Mosquito   263 IETYLLEKARVISQQTLERSYHIFYQIMSGSVKGLKEMCFLSNDIYDYNSVSQGKITIPNVDDGE 327

  Fly   242 DYKGTCNAFKTLGFSTDEVQTIWRTIAAVLHLGNVEFQT--IEDELVISNKQHLKSTAKLLQVTE 304
            :...|..||..|||:.:|...|:|..:||:|:|.::|:.  .|::......:.....||||.|..
Mosquito   328 ECLLTDEAFNVLGFTQEEKDNIYRITSAVMHMGRMQFKQKGREEQAEADGTEDGDRVAKLLGVGT 392

  Fly   305 TELSTALTKRVIAAGGNVMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQAR 369
            .:|...|.|..|..|...:.|..|..|......||.|.|:||||.|::.:.|..:     .|:.:
Mosquito   393 DDLYKNLLKPRIKVGNEFVTKGQNKDQVTNSVGALCKGIFDRLFKWLVKKCNETL-----DTKQK 452

  Fly   370 FNSVIGVLDIYGFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNK 434
            ....||||||.||||||.|.|||.|||:.||||||.|...:...|||||::|||.|..|::..:.
Mosquito   453 RAQFIGVLDIAGFEIFDFNGFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGINWAFIDFGMDL 517

  Fly   435 IIC-DLVEQPHKGIIAIMDEACLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKE----LKH 494
            :.| :|:|:| .||::|::|..: ..|.||.|.   .:|.::.|...::..:||...:    ..|
Mosquito   518 LACVELIEKP-MGILSILEEESM-FPKATDQTF---AEKLMTNHLGKSAPFMKPRPPKPGIPAGH 577

  Fly   495 REDFRITHYAGDVIYNINGFIEKNK----DTLYQDFKRLLHNSKDANLSEMW---------PEGA 546
               |.|.||||.|.|||.|::||||    ||:...||:    ..:|.:.|::         |..|
Mosquito   578 ---FAIGHYAGVVSYNITGWLEKNKDPLNDTVVDQFKK----GSNALMVEIFADHPGQSADPAAA 635

  Fly   547 QDIK-KTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGL 610
            :..: |......|..:.::..:.:|:.||...:|.:||||.||::|::.|.|...|.||:...|:
Mosquito   636 KGGRGKKGAGFATVSSSYKEQLNNLMTTLKSTQPHFVRCIIPNEMKTAGVVDAHLVMHQLTCNGV 700

  Fly   611 LENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFRAGSDRDGVRVLIEEKKFAQ---------- 665
            ||.:|:.|.||.:|..|..|.||||::      |.:|   .||:.|..|.:|.||
Mosquito   701 LEGIRICRKGFPNRMMYPDFKLRYKIL------NPKA---VDGLDVEKEGRKIAQLIIEAVGLNA 756

  Fly   666 -DVKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWIVRRNFKKMKAAITIVRAYKAY 729
             ..:.|.||:|.|: ..|..:|..|:|.:..|::.:|...||::.|:.||||:
Mosquito   757 DQYRLGMTKVFFRA-GVLGQMEEFRDERLSKIMSWMQAWCRGYLSRKEFKKMQ------------ 808

  Fly   730 KLRSYVQELANRLRKAKQMRDYG--KSIQWPQPPLAGRKVEAKLHRMFDFWRANMILHKYPRSEW 792
            :.|..::.:...|||..::|.:.  |..|..:|.|...:||.::.::.:  :|......|.:.|.
Mosquito   809 EQRVSLEIVQRNLRKYLKLRTWAWWKLWQKVKPLLNVSRVEDQIAKLEE--KATKAQEAYEKEEK 871

  Fly   793 PQLRLQIIAATALAGR--------------RPYWGQARRWVG------DYLANSQE--------- 828
            .:..|:.:.:..||.:              :.|..:|.:...      :.|.::||
Mosquito   872 LRKELEALNSKLLAEKTALLDSLSGEKGALQEYQEKAAKLTAQKNDLENQLRDTQERLAQEEDAR 936

  Fly   829 NSGYEAYNGSIKNIRNHPADGETFQ---QVLFSSFVKKFNHFNKQANRAFIVSDSTIHKLDGIKN 890
            |..::......:.|.:...|.|..:   |.:......| :|..:..|......|..|:||    |
Mosquito   937 NQLFQTKKKLEQEIGSQKKDAEDLELQIQKIEQDKASK-DHQIRNLNDEIAHQDELINKL----N 996

  Fly   891 KFKDMKRTIKIRELTSISVSPGRDQLIVFHSSKNK--------DLVFSLESE 934
            |.|.|:.  ::.:.|:..:....|:  |.|.:|.|        :|..|||.|
Mosquito   997 KEKKMQG--EVNQKTAEELQAAEDK--VNHLNKVKAKLEQTLDELEDSLERE 1044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_523538.1	MYSc_Myo1	21..677	CDD:276829	249/713 (35%)
		Myosin_TH1	801..977	CDD:461801	34/174 (20%)
Mhc	XP_061510840.1	None