Protein Alignment Myo31DF and Myo10A

DIOPT Version :10

• Sequence 1: NP_523538.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: XP_061508751.1
• Gene: Myo10A / 1274922
• VectorBaseID: AGAMI1_013284
• Length: 3076
• Species: Anopheles gambiae
• Alignment Length: 955
• Identity: 306/955 - (32%)
• Similarity: 477/955 - (49%)
• Gaps: 92/955 - (9%)

  Fly     6 EAGVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQM-NIYGPETIRKYKGREL 69
            :.||:|...|:.:.....:.||:.|:.||.|||..|.:.:::|||:.. ..||.|..:.|.||.|
Mosquito    97 KTGVEDMTQLEDLHEASLLWNLKLRYDNGLIYTNAGSILIAINPYKMFPESYGIEMAKLYSGRPL 161

  Fly    70 FENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKN 134
            ....||||||..:|:..|...|   .::||||||:||||::|::|:|:|||....|.......:.
Mosquito   162 GTLPPHLFAIGSAAHAALPSPQ---VVVISGESGSGKTESTKLVMQYLAAVVPGGGSASTVITEQ 223

  Fly   135 VLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNF 199
            :| ::..:||.||||:|.|||||||||||:::.|...| .:|..||.|||||||:|.|..||||:
Mosquito   224 IL-EAAPLLEAFGNARTVRNDNSSRFGKYLEVYFKSGA-IIGAKITQYLLEKSRIVTQAAGERNY 286

  Fly   200 HSFYQLLRGANDNELRQYELQKETGKYHYLNQGSMDILTEKSDYKGTCNAFKTLGFSTDEVQTIW 264
            |.||:||.|..:.|..:|.| .|..||.|||||..|....:.|:....:|.:.||.:..|.:.|.
Mosquito   287 HVFYELLGGLAEPERMKYGL-LEADKYFYLNQGGSDCAPGRMDWASLQSAMQVLGVTESEREGIV 350

  Fly   265 RTIAAVLHLGNVEFQTI-----EDELVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVMQ 324
            :.:|:|||||||.|...     ::.:.|.:...:|..|.|||:....:..:||.|:.......:.
Mosquito   351 KVLASVLHLGNVYFHRRQLRHGQEGVEIGSDAEIKWAAHLLQLPSEGILKSLTSRITETRSERLY 415

  Fly   325 KDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSNS 389
            ......||...:||||||:|..||.|::.||| :|:.||....|:   .:.:|||:|||....||
Mosquito   416 TPLGIDQALDARDALAKALYSGLFNWLVLRIN-SIVHRGGTHDAQ---RLSILDIFGFEDLAENS 476

  Fly   390 FEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDEA 454
            |||.||||.||.||..|.:.|.|.||.||.||.:||||:|:.:|..:..|:.:...||..::|:
Mosquito   477 FEQLCINYANESLQLYFNKHVFKLEQAEYARERLEWTNLEWEDNLPVIHLLAKKPVGIFHLLDD- 540

  Fly   455 CLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIYNINGFIEKNK 519
                    :.....|.|.:..:..||.....:...:.....::|.||||||.|.|.::||:|||:
Mosquito   541 --------ESNFPRANDSSFLEKCHYNHALNELYSRPRVGAQEFGITHYAGQVWYCVDGFLEKNR 597

  Fly   520 DTLYQDFKRLLHNSKDANLSEMWPE--GAQDIKKT----------TKRPL--TAGTLFQRSMADL 570
            |.|..|...||.:|.:..:.||..:  ..:|:.||          |.:|.  |....|..|:..|
Mosquito   598 DALRMDVIELLSSSTEPLVGEMTKQLRAQRDVGKTLPKGSNGRFVTMKPRTPTVAARFSDSLQQL 662

  Fly   571 VVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYK 635
            :.::.|..|::|||:|||:.|.:...|...|..|:||||:|:.:::|::|:..|.|:..|:.||:
Mosquito   663 LQSMAKCNPWFVRCVKPNNDKQALRMDMPCVLQQLRYLGMLDTIKIRQSGYPVRLRFQHFVERYR 727

  Fly   636 MISQYTWPNFRAGSDRDGVRVLIEE----KKFAQDVKYGHTKIFIRSP--RTLFALEHQRNEMIP 694
            .:.:...|  :....|:..|.:::|    .....|.:.|.|::|:|..  ||   ||..|.:.:.
Mosquito   728 HLMRTPLP--KGTPYRELCRFVLDELPGTTTEGPDFQLGATRVFLREALHRT---LEASRADRLR 787

  Fly   695 HIVTLLQKRVRGWIVRRNF-KKMKAAITIVRAYKAYKLRSYVQELANRLRKAK-------QMRDY 751
            .....:|:.|||.:.|:.. ::::.|:||.|.::.|:.|:....:.|.:.|.:       |.:.|
Mosquito   788 LAAVTIQRTVRGMLARKKVQREVRGAVTIQRYWRGYRDRNRYLTIKNGVVKYQALYKGHMQRKRY 852

  Fly   752 GKSIQWPQPPLAGRKVEAKLHRMFDFWRANMILHKYPRSEWPQLRLQIIAATALAGRRPYWGQAR 816
            .|.    :..|..|:...:|.:.    |....|.|........:.|.|.|..|
Mosquito   853 AKL----KNELKRRREAERLKKE----RTAQRLAKEQVERGSAVPLDIPAELA------------ 897

  Fly   817 RWVGDYLANSQEN-SGYEAYNGSIKNIRNHPADGET------FQQVLFSSFVKKFNHFNKQANRA 874
                 ::.:..|| ||.::....:|.:...|.....      ..|..|..|...:.:..|.|.|.
Mosquito   898 -----FIFSKSENWSGQQSDRNLVKVVGTVPGPPSAADLPPDLDQFAFGKFSSVYCNGVKLAPRR 957

  Fly   875 FIVSDSTIHKLDGIKNKFKDMKRTIK--IRELTSISVSPGRDQLI 917
            .|:|...:.:.......|||.....|  ||..|..::...|::::
Mosquito   958 DIISAPFLSRAAARDQDFKDAIAIFKLIIRWTTDATMDANREKIL 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_523538.1	MYSc_Myo1	21..677	CDD:276829	248/679 (37%)
		Myosin_TH1	801..977	CDD:461801	24/126 (19%)
Myo10A	XP_061508751.1	None