Protein Alignment Myo31DF and Myo1b

DIOPT Version :10

• Sequence 1: NP_523538.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: XP_038938878.1
• Gene: Myo1b / 117057
• RGDID: 70994
• Length: 1147
• Species: Rattus norvegicus
• Alignment Length: 1165
• Identity: 426/1165 - (36%)
• Similarity: 628/1165 - (53%)
• Gaps: 208/1165 - (17%)

  Fly     8 GVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFEN 72
            ||.|.|||:.::.|.|:|||:|||.:..||||||.|.:|:||||.:.||.||.:..|:.|..:|.
  Rat    16 GVGDTVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYEL 80

  Fly    73 APHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLI 137
            :||:||::|.|||.|:.:.:|.||||:||||||||||||::|.|:|||.....  |:.:||..|:
  Rat    81 SPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGA--EVNQVKEQLL 143

  Fly   138 QSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSF 202
            ||..:||.||||||.|||||||||||||||||:|.||:||:|:||||||||||:|..||||||.|
  Rat   144 QSTPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVF 208

  Fly   203 YQLLRGANDNELR-----------QYELQKETGKYHYLNQGSMDI--LTEKSDYKGTCNAFKTLG 254
            ||||.||::..||           :.:|:::..:|:||:..|..:  :.:.::::...||.:.:|
  Rat   209 YQLLSGASEELLRKSMGASEELLHKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVG 273

  Fly   255 FSTDEVQTIWRTIAAVLHLGNVEFQTIE-----DELVISNKQHLKSTAKLLQVTETELSTALTKR 314
            ||..|.:::...:||||.|||:||:...     ||..|.:|..||...:|..:.:..|..|.:.|
  Rat   274 FSDPEAESVLEVVAAVLKLGNIEFKPESRMNGLDESKIKDKNELKEICELTSIDQVVLERAFSFR 338

  Fly   315 VIAAGGNVMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDI 379
            .:.|....:....|..||.|.:|||||.:|.|||:|:::|||.:|   .::|:.| ..|:|||||
  Rat   339 TVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI---KAQTKVR-KKVMGVLDI 399

  Fly   380 YGFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPH 444
            ||||||:.||||||.||||||||||:||||.||:|||||.||.||||:|:||||.|||||:|...
  Rat   400 YGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNT 464

  Fly   445 KGIIAIMDEACLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPT----DKELKHREDFRITHYAG 505
            .||:|::||.||..|.|||:|.|..:::..:.|.|:.||..|.:    |..|.| ..|||.||||
  Rat   465 NGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTTLPH-SCFRIQHYAG 528

  Fly   506 DVIYNINGFIEKNKDTLYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADL 570
            .|:|.:.||::||.|.||:|..:.:..:..|.:..::||| ...|...|||.|||:.|:.|:|.|
  Rat   529 KVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEG-NPAKVNLKRPPTAGSQFKASVATL 592

  Fly   571 VVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYK 635
            :..|..|.|.|:|||||||.|::.:|.|..|.||:||||||||:||||||:..||.|:..|.|||
  Rat   593 MKNLQTKNPNYIRCIKPNDKKAAHIFSESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYK 657

  Fly   636 MISQYTWPNFRAGSDRDGVRVLIEEKKF-AQDVKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTL 699
            |:.:.|||::: |..|.||.||..|.:. .::..:|.:|||||:|||||.||..|.:.:..:.||
  Rat   658 MLCKQTWPHWK-GPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATL 721

  Fly   700 LQKRVRGWIVRRNFKKMKAAITIVRAY-------KAYK--------LRSYV-----QELANRLRK 744
            :||..|||..|.:|..||.:..::.|:       |.|:        ::||:     :::...|:.
  Rat   722 IQKIYRGWKCRTHFLLMKRSQVVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKH 786

  Fly   745 AKQMRDYGKSI--QWPQPPLAGRKVEAKLHRMFD-------------FWRANMILHKYPRSEWPQ 794
            .|:.::...:|  .|     .|.:...:..|:.|             ||     |....|.|..:
  Rat   787 QKRCKEAATTIAAYW-----HGTQARKERRRLKDEARNKHAIAVIWAFW-----LGSKARRELKR 841

  Fly   795 LRLQIIAATALAGRRPYW-G-QARRWVGDYLANSQENSGYEAYNGSIKNI--------------- 842
            |:.:.....|:|....|| | :.||   :|....:.|:|.:.|..:::.|
  Rat   842 LKEEARRKHAVAVIWAYWLGLKVRR---EYRKFFRANAGKKIYEFTLQRIVQKYLLEMKNKMPSL 903

  Fly   843 ----RNHPAD------------------------------------------------------- 848
                :|.|:.
  Rat   904 SPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPS 968

  Fly   849 --GETFQ---------------------QVLFSSFVKKFNHFN-KQANRAFIVSDSTIHKLDGIK 889
              |:.||                     :::.:..|.|.|..| |..:|.|:::::.:...|
  Rat   969 SVGQPFQGAYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLAD--- 1030

  Fly   890 NKFKDMKRTIKIRELTSISVSPGRDQLIVFH------SSKNKDLVFSLESEYTPLKEDRIGEVVG 948
            .|...:|..:.:.::|.:|:|...|.....|      ::...|.:||.:            .::.
  Rat  1031 QKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSD------------HLIE 1083

  Fly   949 IVCKKYH-DLTGTELRVNVTTN----ISCRLDGKARIITVEA-ASNVEVPNFRPKEGNII 1002
            :..|.|. .|:.|:.::|:..:    :..|.| |..:..::. ..|..||..:.|...::
  Rat  1084 MATKLYRTTLSQTKQKLNIEISDEFLVQFRQD-KVCVKFIQGNQKNGSVPTCKRKNNRLL 1142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_523538.1	MYSc_Myo1	21..677	CDD:276829	334/678 (49%)
		Myosin_TH1	801..977	CDD:461801	42/286 (15%)
Myo1b	XP_038938878.1	MYSc_Myo1	29..699	CDD:276829	334/678 (49%)
		IQ	760..782	CDD:197470	2/21 (10%)
		Myosin_TH1	952..1129	CDD:461801	29/192 (15%)