DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6144 and alkbh6

DIOPT Version :9

Sequence 1:	NP_001033895.1	Gene:	CG6144 / 34443	FlyBaseID:	FBgn0032259	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_001005390.1	Gene:	alkbh6 / 317736	ZFINID:	ZDB-GENE-060407-1	Length:	234	Species:	Danio rerio

Alignment Length:	225	Identity:	106/225 - (47%)
Similarity:	151/225 - (67%)	Gaps:	4/225 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFTGFEVRKCPPTVMYIPNFITSEEEQRILSHIERTPKPRWTQLLNRRLVNYGGVPHPNGMIAE 65
            :|...:.|::.||||.|||:||:..||:.:|..:.|.|||:||||..|||.|:||:|:|.||:||
Zfish     9 VDLEKYIVKEAPPTVYYIPDFISEAEEEFLLQQVYRAPKPKWTQLSGRRLQNWGGLPNPKGMLAE 73

  Fly    66 EIPEWLQTYVDKVNNLGVFESQNANHVLVNEYLPGQGILPHTDGPLFHPIISTISTGAHTVLEFV 130
            ::|:||..|.:|::.||.|..:.|||||||||.||:||:||.||||:||.::||:.|:||:|:|.
Zfish    74 KLPDWLLEYTEKISALGAFAGKTANHVLVNEYKPGEGIMPHEDGPLYHPTVTTITVGSHTLLDFY 138

  Fly   131 KREDTTTETEAGDQTTREVLFKLLLEPRSLLILKDTLYTDYLHAISETSEDVLCDRISNYDLCEN 195
             |.....|.:|........:..||::.:|||||:|.:|..|||.|....||||.:.:.|  :...
Zfish   139 -RPVCQAEPDAPQTEESRYMLSLLVQRKSLLILQDDMYKCYLHGIRGVCEDVLSEHVVN--ISST 200

  Fly   196 TYKIGDHLVRRSPRISLTIRNVPKTSKMKL 225
            ..::||.| .||.|:|||||:|||..:..|
Zfish   201 GAQVGDTL-PRSTRVSLTIRHVPKIIRANL 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6144	NP_001033895.1	2OG-FeII_Oxy	15..215	CDD:304390	95/199 (48%)
alkbh6	NP_001005390.1	2OG-FeII_Oxy	23..219	CDD:304390	95/199 (48%)
		Alpha-ketoglutarate binding. /evidence=ECO:0000250	103..105		1/1 (100%)
		Alpha-ketoglutarate binding. /evidence=ECO:0000250	213..219		4/5 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596126
Domainoid	1	1.000	154	1.000	Domainoid score	I4225
eggNOG	1	0.900	-	-		E1_KOG3200
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15555
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3581
OMA	1	1.010	-	-		QHG58390
OrthoDB	1	1.010	-	-		D1573279at2759
OrthoFinder	1	1.000	-	-		FOG0005546
OrthoInspector	1	1.000	-	-		oto40067
orthoMCL	1	0.900	-	-		OOG6_103545
Panther	1	1.100	-	-	LDO	PTHR46030
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3661
SonicParanoid	1	1.000	-	-		X4499
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800