Protein Alignment Cog4 and cog4

DIOPT Version :10

• Sequence 1: NP_609413.1
• Gene: Cog4 / 34442
• FlyBaseID: FBgn0032258
• Length: 776
• Species: Drosophila melanogaster
• Sequence 2: XP_031755720.1
• Gene: cog4 / 100145689
• XenbaseID: XB-GENE-6085196
• Length: 772
• Species: Xenopus tropicalis
• Alignment Length: 788
• Identity: 303/788 - (38%)
• Similarity: 474/788 - (60%)
• Gaps: 41/788 - (5%)

  Fly     2 SVLEQLGALDIGTNEQVDETLQRIADEEAKVNEKLESLLAKQCQIEAKMSGIGRSLSLLHTVDSD 66
            |||.......:...:.:.|..:|:..||..|..:|.:||.:|..:|.||..:.|....|..::.|
 Frog    13 SVLSMEHVRSLTDLQDLKEAYERLCAEEKDVESELLTLLGQQTIVEKKMLALQRMGPNLQLIEGD 77

  Fly    67 SNKLNDQIVNTAQLAESVSAKVRRLDLARCRASECQQRVHDLIDLHLCSQGVVKAIGEEDYEKSA 131
            :.:|:..|..|..|||:||:|||:||||:.|..:..||..|::||..|..||..|:..||||::|
 Frog    78 AQQLSGMITFTCNLAENVSSKVRQLDLAKSRLYQAIQRADDILDLKFCMDGVQTAMKNEDYEQAA 142

  Fly   132 THIARFLAMDQQLLRRTADDVQGSITSVSDAVKTLEDATEKTRVLIAKRFDEAVKADDLASVERF 196
            .||.|:|.:|:.::..:....:|:|...:  :..|::|.:..:|:::::||.|.|:.||..||||
 Frog   143 AHIHRYLCLDKSVIELSRQGKEGNIIEAN--LHHLQEAEQHLKVVVSEKFDAATKSGDLPQVERF 205

  Fly   197 FKIFPLVGCHRTGIEKFSLYICQKLANKAQKELRNAQDIAKAESRLQLAYADRLTAILENFARVV 261
            ||||||:|.|..||.|||.|:|:::|.||::.|:.|......|.|..|.:||.||.:.|..||:|
 Frog   206 FKIFPLLGLHEEGISKFSGYLCKQVAKKAEENLQLALGTEGGERRAALIFADTLTLLFEGIARIV 270

  Fly   262 EVNQPIIEAFYGQASSSLIDMVSILQHECDTEVKNLLMEFNKNRQIQYRSKQVNESTQRSAGGGN 326
            |.:|||:|.:||  ...|..::..||.|||.:|:.::.:|.::|....:.:||.....|
 Frog   271 ETHQPILETYYG--PGRLYMLIKHLQAECDRQVEKVVDKFVQHRDYHRKFQQVQSCMMR------ 327

  Fly   327 LGSNSIQALGHYRKPSGGSVDKLNPKEIDAIIAEITVMHARVELYFRFMRRRLQVHVE---TCVP 388
                            |.|.||:.|:::|.|::|:|:|.||.|||.||::||:....|   :...
 Frog   328 ----------------GSSTDKIEPRDLDPILSEVTLMSARTELYLRFIKRRVVSDFEVGDSMAT 376

  Fly   389 EKEQFDIMERYEKIMKNSDLRRQMQEILSTYLLLERYFMEESVLKAIGLDTYESGQQCSSMVDDV 453
            |:.:.:.::..:|::|:..|...:||::..|:.:|.::|.|||.||:.:||.|.||..|||||||
 Frog   377 EEVKQEHLQNLDKLIKHCLLSCSVQELIGYYITMEEFYMRESVNKAVAMDTCERGQLISSMVDDV 441

  Fly   454 FFILRKSIRRALTTQSINGTCAVINNVAACLDGDFVNALKAPLKSGYPSGYID-----LAQAYNA 513
            |:|::|.|.|||::.||:..||:||.....|:.||...|...|:.|:|:....     :..|.|.
 Frog   442 FYIVKKCIGRALSSSSIDCLCAMINLSTTMLESDFREVLCNKLRMGFPATTFQDIQRGVTSAVNL 506

  Fly   514 IQTSLQQGKLHS---SDADRGRANFLVQLNNADISTEYIETLCQTMEQEIAGTFPQTTQVE--RQ 573
            :|:||||||..:   ...|..:.:|||.|||.::.:|.|.||.:.:|.:....|.|....|  :.
 Frog   507 MQSSLQQGKFDTKGIESNDEAKMSFLVSLNNVEVCSENIMTLKKNLENDCNKMFSQGLGGEQAKA 571

  Fly   574 MLDSCLTELKAVRDALKATVDFGMQQLRSSVIKPRLNPWINQFLNYSHNLNEEELAAYEAGETFV 638
            .:||||:::.:|.:..|..:..|:.:|.|:.:||::.||||.||:.|||:.|||...|||.:.:|
 Frog   572 KIDSCLSDMASVSNKFKDLLQEGLGELNSTAVKPQVKPWINLFLSVSHNIEEEEFNDYEANDPWV 636

  Fly   639 QFFIVQLDGLLNSFKNSLSPRNYDALVSILATEVTIQLERAIKKISFNRLGGLVLDQEVRALGSY 703
            |.|||.|:.|:..||..||...|:.|.|:|.:.:.::||:.:.|.:|:|||||..|:|:|:|.:|
 Frog   637 QQFIVNLEQLMAEFKAGLSSVIYENLTSLLTSLIAMELEKVVLKSTFSRLGGLQFDKELRSLIAY 701

  Fly   704 LTGATSWSVRDKMTRISQIATLLNLDKITELSEYWNPENNKEMSSWHLTPNEVRTFLTLRNDFRI 768
            ||..|:|::|||..|::|:||:|||:::||:.:||.|  |....:|.|||.|||..|.||.|||.
 Frog   702 LTTVTTWTIRDKFARLTQMATILNLERVTEILDYWGP--NSGPLTWRLTPAEVRQVLALRIDFRS 764

  Fly   769 EDIKRLQL 776
            ||||||:|
 Frog   765 EDIKRLRL 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cog4	NP_609413.1	Cog4	166..497	CDD:214809	126/333 (38%)
cog4	XP_031755720.1	COG4	175..484	CDD:462425	126/332 (38%)