Protein Alignment Grip75 and SPC98

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_014273.1
• Gene: SPC98 / 855597
• SGDID: S000005070
• Length: 846
• Species: Saccharomyces cerevisiae
• Alignment Length: 656
• Identity: 125/656 - (19%)
• Similarity: 230/656 - (35%)
• Gaps: 218/656 - (33%)

  Fly    15 EQLGIKAFNETTVIDQF----IHPCEREIFMDIIKIIKVYQEVEQFTHSSGRKSDTHGELPDSLH 75
            :.||.|       :::|    |.|.::.:      ||::.:|::.:|
Yeast   232 QSLGYK-------VEKFRMLNISPMKKAL------IIEISEELQNYT------------------ 265

  Fly    76 GYYLLNL-AKGIEMALEEYYAEIG----RLEKYCLGNERNSLSYVYNALYAKFPLLVFMRNLITE 135
             .::.|| :.|..::|:..|.||.    ||..||...|
Yeast   266 -AFVNNLVSSGTVVSLKSLYREIYENIIRLRIYCRFTE--------------------------- 302

  Fly   136 IHVLNLRGCVLLHNLHQQCEHGDIQLEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFI-K 199
             |:..|.|...|..|:....|||:.:.|....:...:.:.::..|.:||..|::...:.|||| :
Yeast   303 -HLEELSGDTFLIELNIFKSHGDLTIRKIATNLFNSMISLYYEYLMNWLTKGLLRATYGEFFIAE 366

  Fly   200 FTPTDAVDGSSFSKSATCSLLSAEKNPEDYIWQ--YEVNMSQLPGFFSIVLAEKVLFVGQTVLVF 262
            .|.|:..|                   :|:|:.  .|.|..::|.|....||.|:..:|::.:..
Yeast   367 NTDTNGTD-------------------DDFIYHIPIEFNQERVPAFIPKELAYKIFMIGKSYIFL 412

  Fly   263 KMGRNVKVKNKTDPLAAKLAELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDIKN 327
            :  :..|....|:..:.|...|...:.|:   |..:.||:::.|..:|              |.|
Yeast   413 E--KYCKEVQWTNEFSKKYHVLYQSNSYR---GISTNFFEIINDQYSE--------------IVN 458

  Fly   328 YVSARLSEIAVNEVDLERQMGLIKDFFLLGRGEF---YLEFCSQMVGT----METYREERFKNVT 385
            :.:..|::    :......:..:|:..|:|:.:|   .:|..:.::.|    :..|:      :|
Yeast   459 HTNQILNQ----KFHYRDVVFALKNILLMGKSDFMDALIEKANDILATPSDSLPNYK------LT 513

  Fly   386 RSFELAATVTGITDDLDKFSLICQRSTSEPDDTSDFNFLQG--------------LSLKYEYEWP 436
            |..:.|..::.:           :...:.|.::|..|.|..              .:|.|....|
Yeast   514 RVLQEAVQLSSL-----------RHLMNSPRNSSVINGLDARVLDLGHGSVGWDVFTLDYILYPP 567

  Fly   437 LNLLFS---PTTIERYNNIFRFLLIIRTYQYEIQRVWAKQTWRAKSAKDVPPNNKII-------- 490
            |:|:.:   |...:.|..||.||...:...|..|:...|.....:|.|.:...|.:|
Yeast   568 LSLVLNVNRPFGRKEYLRIFNFLWRFKKNNYFYQKEMLKSNDIIRSFKKIRGYNPLIRDIINKLS 632

  Fly   491 ---TLRNYLMFFLNNMQYYIQVDVLESQFGILMNVI-----KSRSDFEVI--------------- 532
               .||.....|.:.|:.|....::|..|..:...:     ||::.|::|
Yeast   633 RISILRTQFQQFNSKMESYYLNCIIEENFKEMTRKLQRTENKSQNQFDLIRLNNGTIELNGILTP 697

  Fly   533 ---------------------------QRAHTVFLANVLSH-CFLLNESETQLNVTGSQNRNPIY 569
                                       :..|..||.|:||| .|..|.||..:   |..:..| |
Yeast   698 KAEVLTKSSSSKPQKHAIEKTLNIDELESVHNTFLTNILSHKLFATNTSEISV---GDYSGQP-Y 758

  Fly   570 GTLLKL 575
            .|.|.|
Yeast   759 PTSLVL 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	65/336 (19%)
		GCP_C_terminal	349..642	CDD:461187	60/310 (19%)
SPC98	NP_014273.1	GCP_N_terminal	185..467	CDD:465456	65/336 (19%)
		GCP_C_terminal	476..823	CDD:461187	60/310 (19%)