Protein Alignment Grip75 and tubgcp3

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: XP_005171052.1
• Gene: tubgcp3 / 563517
• ZFINID: ZDB-GENE-030616-538
• Length: 906
• Species: Danio rerio
• Alignment Length: 687
• Identity: 144/687 - (20%)
• Similarity: 262/687 - (38%)
• Gaps: 134/687 - (19%)

  Fly    30 QFIHPCEREIFMDI---IKIIKVYQEVEQ------FTHSSGRK-SDTHGELPDSLHGYYLLNLAK 84
            :||..|..|....|   :.:.|..::...      :.|:..|| :|:|.  .|...|....:...
Zfish   262 KFIKMCSPENCYKIDSKVPLCKSLRDTSSRLAELGWLHNKIRKYTDSHS--LDRAFGLVGQSFCA 324

  Fly    85 GIEMALEEYYAEIGRLEKYCLGNERNSLSYVYNALYAKFPLLVFMRNLITEIHVL--------NL 141
            .:...|:|||..:..|.......:...::...::......|||:..:....:..|        ..
Zfish   325 ALHQELKEYYRLLSVLHAQLQVEDDQGVNMSVDSSLTLRRLLVWTYDPKVRLKTLAALVDYCQGR 389

  Fly   142 RGCVLLHNLHQQCEHGDIQLEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAV 206
            :|..|...:|...:.||..:...|:.|:..|.:...:.|..|:..|.::|.:.|||:...||...
Zfish   390 KGGELATAVHAYGKTGDPNMRALIQHILGLVSHPILNFLYRWIYDGELEDTYHEFFVASDPTVKT 454

  Fly   207 DGSSFSKSATCSLLSAEKNPEDYIW--QYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVK 269
                                 |.:|  :|.:..|.:|.|.::..|.|||.:|:::...    :..
Zfish   455 ---------------------DRLWHDKYSLRKSMIPSFITMDQARKVLLIGKSINFL----HQV 494

  Fly   270 VKNKTDP---LAAKLAELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDI--KNYV 329
            ..::|.|   :.|..::....|..:|::..|.. |:..:|.:      .|...|.::|:  |||
Zfish   495 CHDRTPPGKIMPASKSKDSPKDAAELFTDLEGT-FQSKIDAA------YFETSKYLLDVLNKNY- 551

  Fly   330 SARLSEIAVNEVDLERQMGLIKDFFLLGRGEFYLEFCSQMVGTMETYREERFK--------NVTR 386
                        .|...:..::.:.|||:|:|....       |:..:.|..:        |:|.
Zfish   552 ------------QLLEHLQAMRRYLLLGQGDFIRHL-------MDLLKPELARPATTLYQHNLTG 597

  Fly   387 SFELAATVTGITDDLDKF--SLICQRSTSEPDDTSDFNFLQGLSLKYEYEWPLNLLFSPTTIERY 449
            ..|.|...|....|..:.  .|..:.....|.||....|    ||.|..|.|:..:|:...:..|
Zfish   598 ILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVF----SLDYHVEGPIATVFTRECMSHY 658

  Fly   450 NNIFRFLLIIRTYQYEIQRVWAKQTWRAKSAKDVPPNNKII----TLRNYLMFFLNNMQYYIQVD 510
            ..:|.||...:..:|.:..:|..|...||..|.:|..:.::    .|.:.::.|::.|||||..:
Zfish   659 LRVFNFLWRAKRMEYILTDIWKGQMCNAKLLKSMPELSGVLHQCHVLASEMVHFIHQMQYYITFE 723

  Fly   511 VLESQFGILMNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQLN--------VTGSQN-RN 566
            |||..:..|.|.::...|.:.|..||.|||..::|.|.|...:.:.||        :...|| ::
Zfish   724 VLECSWDELWNKVQQAQDLDHIIAAHDVFLDTIISRCLLDVNNRSLLNQLRAVFDQIIEFQNAQD 788

  Fly   567 PIYGTLLK-------------------LFGI-----CEKFAHMTQTKDPSDDLEDEVDQLNESFG 607
            .:|.:.|:                   .:|:     .|:...:.:.||....:..::..|...:.
Zfish   789 TLYRSALEELQLRIQFEDKKRQREEMAEWGVTAEQEAEENRRVQEFKDTIPKMCSQLRLLTHFYQ 853

  Fly   608 VQIASLIQLLVDVKSASCLGPLSQLLLRLDFNCWFSA 644
            ..:...::||:.....|    |..|..|||||..:.|
Zfish   854 GIVQEFLRLLMTCSDES----LQFLSFRLDFNEHYKA 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	64/334 (19%)
		GCP_C_terminal	349..642	CDD:461187	78/339 (23%)
tubgcp3	XP_005171052.1	GCP_N_terminal	249..549	CDD:465456	61/320 (19%)
		GCP_C_terminal	553..884	CDD:461187	79/345 (23%)