Protein Alignment Grip75 and tubgcp4

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_001128602.1
• Gene: tubgcp4 / 557155
• ZFINID: ZDB-GENE-081022-124
• Length: 668
• Species: Danio rerio
• Alignment Length: 716
• Identity: 202/716 - (28%)
• Similarity: 327/716 - (45%)
• Gaps: 122/716 - (17%)

  Fly     1 MIHDLLLACRSHNP-------EQLGIKAFNETTVIDQFIHPCEREIFMDIIKI----IKVYQEVE 54
            |||:||||...: |       ::.|::...:.    .|:||.|..:...:.|:    ::..:.:|
Zfish     1 MIHELLLALSGY-PGTIFTWNKRNGLQVSQDL----PFLHPSETSVLNRLCKMGTDYVRFTEFIE 60

  Fly    55 QFT-------HSSGRKSDTHGELPDSLHGYYLLNLAKGIEMALEEYYAEIGRLEKYCLGNERNSL 112
            |.|       |.|.:.|.:      .|||.||.....|:...|:.|...:..|||..||:...|:
Zfish    61 QHTGHVHQQEHYSSQPSQS------GLHGIYLRAFCTGLHSMLQPYRQALLDLEKEFLGDPHLSI 119

  Fly   113 SYVYNALYAKFPLLVFMRNLITE-IHVLNLRGCVLLHNLHQQCEHGDIQLEKAIKIIMKPVKNAF 176
            |:| |.:..:|.||.....::.| |....:.||.:|..:::....|...:..|::.|:.......
Zfish   120 SHV-NYMLEQFQLLFPSVMVVVETIKSQKIHGCQILETVYKHSCGGLPPVRMALEKILAVCHGVM 183

  Fly   177 FSSLAHWLLFGVIDDVHSEFFIKFTPT-----------------DAVDGSSFSKSATCSLLSAEK 224
            :..||.|:|.|::.|...|||:|..|:                 ..:.|....:.....|:..|.
Zfish   184 YKQLAAWMLHGLLLDQSEEFFVKQGPSAGGATAAQEEDEEDLGIGGLSGKQLRELQDLRLIEEEN 248

  Fly   225 NPEDYIWQYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVK-------VKNKTDPLAAKLA 282
            .....:.|:.:.:..||.:..:.:|||:||||::|.:|: ..|..       :|::.|..||:|.
Zfish   249 MLAPSLQQFSLRVEMLPSYIPVRVAEKILFVGESVQMFE-NHNQSPSRAGSILKHQEDMFAAELH 312

  Fly   283 ELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIID-IKNYVSARLSEIAVNEVDLERQ 346
            .|....::.|            ||..|            ::| |::.|:..|..:.|.|.||..|
Zfish   313 RLKQQPLFSL------------VDFEN------------LVDGIRSTVAEHLWTLMVEESDLLGQ 353

  Fly   347 MGLIKDFFLLGRGEFY---LEFCSQMVGTMETYREERFKNVTRSFELAATVTGITDD--LDKFSL 406
            :.:|||||||||||.|   ::....|:.|..:...|...||  :|:.||....:.||  |....|
Zfish   354 LKIIKDFFLLGRGELYQVFIDLAQHMLKTPPSAVTEHDVNV--AFQQAAHKVLLDDDNLLPLLHL 416

  Fly   407 IC-------------QRSTSEPDDTSDFNF----LQGLSLKYEYEWPLNLLFSPTTIERYNNIFR 454
            ..             :..|:.|.::|....    ...|.|.|:.:|||::||:|..:|:||.:||
Zfish   417 TIDYHGKESKEGSGNREGTTPPQESSPREAPPTGWAALGLAYKVQWPLHILFTPAVLEKYNVVFR 481

  Fly   455 FLLIIRTYQYEIQRVWAKQTWRAKSAKDVPPNNKIITLRNYLMFFLNNMQYYIQVDVLESQFGIL 519
            :||.:|..|.|:|..||.|..| |..|....:.....|||::.|.::|:|||:|||||||||..|
Zfish   482 YLLSVRRVQSELQHCWALQMQR-KHLKSNQTDAVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQL 545

  Fly   520 MNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGICEKFAH 584
            :..|.|..|||.|:.||..||:|:|:..|:|              ..|::..|.::..:|..|..
Zfish   546 LQQINSTRDFESIRLAHDHFLSNLLAQSFIL--------------LKPVFHCLNEILDLCHNFCS 596

  Fly   585 MTQTKDPSDDLED--EVDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLLLRLDFNCWFSASHN 647
            :......|.|...  ::|.|.:.|..|...|.::|..|::......|:|||||||:|.:::.:..
Zfish   597 LVSQNLGSLDERGTAQLDILVKGFSRQSFLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGG 661

  Fly   648 T 648
            |
Zfish   662 T 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	89/381 (23%)
		GCP_C_terminal	349..642	CDD:461187	107/316 (34%)
tubgcp4	NP_001128602.1	GCP_N_terminal	2..347	CDD:465456	89/381 (23%)
		GCP_C_terminal	350..656	CDD:461187	109/322 (34%)