Protein Alignment Grip75 and Grip163

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_648537.2
• Gene: Grip163 / 39365
• FlyBaseID: FBgn0026432
• Length: 1351
• Species: Drosophila melanogaster
• Alignment Length: 662
• Identity: 128/662 - (19%)
• Similarity: 232/662 - (35%)
• Gaps: 143/662 - (21%)

  Fly    29 DQFIHPCEREIFMDIIKIIKVYQEVEQFTHSSGRKSDTHGELPDSLHGYYLLNLAKGIEMALEEY 93
            ||| ..|...:.:         ||.:....::...|..|.|:|..::..  ||.....|:
  Fly   779 DQF-QQCHATVHL---------QESDLLKTAASTSSGLHAEIPQDINAN--LNCPDTKEL----- 826

  Fly    94 YAEIGRLEKYCLGNERNSLSYVYNALYAKFPLLVFMRNLITEIHVLNLRGCVLLHNLHQQCEHGD 158
             .|:.|..|   .||.:...:.:|:              ..:.|...||..     |:...|.|.
  Fly   827 -TELQRNRK---RNEHHDGFFSFNS--------------TEDEHTHRLRSL-----LNSNTERGR 868

  Fly   159 IQLEKAIKIIMKP-----VKNAFFSSLAHWLLFGVIDDVHSEF-FIKFTPTDAVDGSSFSKSATC 217
            .:|.     :|:.     .||....:.|...|...||.:|.|. ....||........|...
  Fly   869 NRLR-----VMETEFGLGYKNTDIETKATPCLPLEIDKLHVEIPLAVLTPMSTTSDVDFGDP--- 925

  Fly   218 SLLSAEKNPEDYIWQYEVNMSQLPGFFSIVLAEKVLFVGQ-TVLVFKMGRNVKVKNKTDPLAAKL 281
               |..:.||........|:|......|..|.:.||.:.: |.|:.|:...:|.:.:|
  Fly   926 ---SPRELPEIADTANNNNVSGSIESLSPELPKPVLAIAKPTSLLPKLDFGMKDERET------- 980

  Fly   282 AELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEI--AVNEVDLE 344
             |.|.|.:..|.........:..:.||            |:..:..|.....:|:  ...|..:.
  Fly   981 -EQDRDKVSTLPEACNPFMARRCLQLS------------VMAPLNAYYGLLRNEVLRIFQEQRIY 1032

  Fly   345 RQMGLIKDFFLLGRGEFYLEFCSQMVGTM------ETYREERFKNVTRSFELAATVTGITDDLDK 403
            .....::::|.|..|:|.....::::|.:      .:..::...:...:..|||.....|...:.
  Fly  1033 EHFRKLRNYFFLVDGQFGATLTNEILGRIRAGVGPRSLSQKGILDTILTNALAACSADETTVSEN 1097

  Fly   404 FSLICQRSTSEPDDTSDFNFL-----QGLSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIR--- 460
            .:|.|   |:.||   ..|||     ..|.|..:.:||||::.|..||.:|..||.:||.:|
  Fly  1098 LTLNC---TTIPD---TLNFLSVEATSMLKLNCKIDWPLNMVISSETISKYGQIFGYLLKLRHVS 1156

  Fly   461 -----TYQYEIQRVWAKQTWRAKSAKDVPPNNKIIT-------LRNYLMFFLNNMQYYIQVDVLE 513
                 ||:| :|::          .|.:.|..:..|       :|:.:..|:.:.|.::....|.
  Fly  1157 FVLDGTYEY-LQQM----------GKLLGPELRTCTHFRHMQMMRHKMSHFMTSFQTHLVAKALL 1210

  Fly   514 SQFGILMNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGI 578
            |.:......:.:....|.:.:.|..:|..| :...|||....:           :..|:..:..|
  Fly  1211 STWKSFKEELCTADSIEALYKQHVAYLKRV-AFLALLNRRSAK-----------VKETIDNILVI 1263

  Fly   579 CEKFAHMTQTKDPSDDLED--------EVDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLLLR 635
            ..:|..:.|::....|.::        .:.|....|...:..||.|.....::.....:..|:..
  Fly  1264 ILRFCKVIQSQSFIVDQDNYFVHPRFKRLQQEEAEFEKFLQYLIYLGNKAAASGYQEEIGDLICI 1328

  Fly   636 LDFNCWFSASHN 647
            ::||.::..|.|
  Fly  1329 INFNHYYKVSGN 1340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	61/319 (19%)
		GCP_C_terminal	349..642	CDD:461187	64/326 (20%)
Grip163	NP_648537.2	GCP_N_terminal	273..523	CDD:465456
		EnvC	<532..>677	CDD:443969
		GCP_C_terminal	1033..1335	CDD:461187	64/330 (19%)