Protein Alignment Grip75 and tubgcp2

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_956416.1
• Gene: tubgcp2 / 386975
• ZFINID: ZDB-GENE-031118-150
• Length: 882
• Species: Danio rerio
• Alignment Length: 720
• Identity: 146/720 - (20%)
• Similarity: 270/720 - (37%)
• Gaps: 203/720 - (28%)

  Fly    27 VIDQFIHPCEREIFMDIIKIIKVYQEVEQFTHSSGRKSDTHGELPDSLHGYYLLNLAKGIEMALE 91
            ::|..:....:|:...|:.:...|..:.:||..  :.|..:|::..:        |...:...::
Zfish   247 IVDPSLDLSVKELVNRILPVASCYSTITRFTEE--KSSFEYGQVNHA--------LTAAMRTLMK 301

  Fly    92 EYYAEIGRLEKYCLGNERNSLS------YVYNALYAKFPLLVFMRNLITEIHVLNLRGCVLLHNL 150
            ||...:.:||..   :.:.:||      |:...:..    :..:.::.|.:......|...|..|
Zfish   302 EYLILVTQLEHL---HRQGTLSLQKLWFYIQPTMRT----MEILASIATSVEKGECMGGSTLSLL 359

  Fly   151 HQQCEH--GDIQLEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSK 213
            |.:..:  ||.|.::....:.|.....:|..|..|:..|:|.|.:|||.::...
Zfish   360 HDRTFYYTGDSQAQELCLYLTKAASVPYFEILEKWIYRGIIKDPYSEFMVEEHE----------- 413

  Fly   214 SATCSLLSAEKNPEDY---IW--QYEVNMSQLPGFFSIVLAEKVLFVGQTV-LVFKMGRNVKVKN 272
                  |..||..|||   .|  :|.:...::|.|.. .:|:|:|..|:.: :|.:.||:|
Zfish   414 ------LQKEKIQEDYNDKYWDQRYTIVQHRIPSFLQ-KMADKILNTGKYLNVVRECGRDV---- 467

  Fly   273 KTDPLAAKLAELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEIA 337
             |.|        |:.::  |::.:|..:              |.::||...    |.|..|.:..
Zfish   468 -TCP--------DAKEV--LYTLKERAY--------------VEQIEKAYY----YASKVLLDFL 503

  Fly   338 VNEVDLERQMGLIKDFFLLGRGEFYLEFCSQMVGTMETYREERFKNV--------TRSFELAATV 394
            :.|.:|..::..||.:||:.:|:|::.|       |:...||..|.|        ....|||..:
Zfish   504 MEEKELVSRLRSIKHYFLMDKGDFFVHF-------MDLTEEELKKPVDDIIPPRLEALLELALRM 561

  Fly   395 -TGITD--------DLDKFSLICQR--------------STSEPDDTSDFNFLQGLSLKYEYEWP 436
             |..||        ||....:|.|.              ..:||.:.| .:.|:..|..|..:||
Zfish   562 STANTDPFKDDLKIDLMPHDVITQLLRVLAIDTKQEKAIINAEPTEVS-LSGLEAFSFDYIVKWP 625

  Fly   437 LNLLFSPTTIERYNNIFRFLLIIRTYQYEIQRVW-----AKQ------TWRAKSAKDVPPNNKII 490
            |:|:.:...:.||..:||.:...:..:..:..||     .||      .|.|.:          .
Zfish   626 LSLIINRKALTRYQMLFRHMFYCKHVERLLCNVWISNKATKQYSLHTAKWFAAA----------F 680

  Fly   491 TLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESET 555
            .||..::.|:.|:|||:..:|:|..:.::.|.:|:.|:.:.:...||.||.|.|..|.|.|....
Zfish   681 ALRQRMLNFVQNIQYYMMFEVMEPTWHVMENNLKTASNIDDVLCHHTSFLDNCLKDCMLTNPELL 745

  Fly   556 QLNVTGSQNRNPIYGTLLKLFGICEKFAHMTQ--------------------TKDPSDDLEDE-- 598
            ::              ..||..:|..|.:..|                    |.:.:..|.||
Zfish   746 RI--------------FSKLMSVCVMFTNCMQRFTQSMRIDSEMKRLTLEHGTIEGTSVLADEAE 796

  Fly   599 -------------------------VDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLLLRLDF 638
                                     :.:.:.:|...:..|:..|....:..|...:..::.||||
Zfish   797 KKRLASKFLAEHVDALQSDSGFEGTISKFDSNFSTLLLDLLDKLSIYSTNDCEHSMINIIYRLDF 861

  Fly   639 NCWFS 643
            |.:::
Zfish   862 NGFYT 866

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	63/326 (19%)
		GCP_C_terminal	349..642	CDD:461187	81/381 (21%)
tubgcp2	NP_956416.1	GCP_N_terminal	218..506	CDD:465456	63/326 (19%)
		GCP_C_terminal	509..865	CDD:461187	82/387 (21%)