Protein Alignment Grip75 and Tubgcp4

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_001386209.1
• Gene: Tubgcp4 / 362203
• RGDID: 1306924
• Length: 667
• Species: Rattus norvegicus
• Alignment Length: 713
• Identity: 202/713 - (28%)
• Similarity: 335/713 - (46%)
• Gaps: 117/713 - (16%)

  Fly     1 MIHDLLLACRSHNPEQLGIKAFNETTVID-----QFIHPCEREIFMDIIKI----IKVYQEVEQF 56
            |||:||||...:..   .|..:|:.:.:.     .|:||.|..:...:.::    |:..:.:||:
  Rat     1 MIHELLLALSGYPG---SIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQY 62

  Fly    57 THSSGRKSDTH----GELPDSLHGYYLLNLAKGIEMALEEYYAEIGRLEKYCLGNERNSLSYVYN 117
            | ...::.|.|    |:  ..|||.||.....|::..|:.|...:..||:..|.:...|:|:| |
  Rat    63 T-GHVQQQDHHPSQQGQ--GGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLADPHLSISHV-N 123

  Fly   118 ALYAKFPLLV-FMRNLITEIHVLNLRGCVLLHNLHQQCEHGDIQLEKAIKIIMKPVKNAFFSSLA 181
            ....:|.||. .:..::.:|....:.||.:|..:::....|...:..|::.|:.......:..|:
  Rat   124 YSLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLS 188

  Fly   182 HWLLFGVIDDVHSEFFIKFTPTD-----------------AVDGSSFSKSATCSLLSAEKNPEDY 229
            .|:|.|::.|.|.|||||..|:.                 .:.|....:.....|:..|......
  Rat   189 AWMLHGLLLDQHEEFFIKQGPSSGNVSAQMEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPS 253

  Fly   230 IWQYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVK-------VKNKTDPLAAKLAELDSD 287
            :.|:.:.:..||.:..:.:|||:||||::|.:|: .:||.       :||:.|..||:|..|...
  Rat   254 LKQFSLRVEILPSYIPVRVAEKILFVGESVQMFE-NQNVNLTRKGSILKNQEDTFAAELHRLKQQ 317

  Fly   288 DIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIKD 352
            .::.|            ||           .|:|:..|::.|:..|.::.|.|.||..|:.:|||
  Rat   318 PLFSL------------VD-----------FEQVVDGIRSTVAEHLWKLMVEESDLLGQLKIIKD 359

  Fly   353 FFLLGRGEFYLEF---CSQMVGTMETYREERFKNVTRSFELAATVTGITDD--LDKFSL------ 406
            |:||||||.:..|   ...|:.|..|...|...||  :|:.:|....:.||  |....|
  Rat   360 FYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNV--AFQQSAHKVLLDDDNLLPLLHLTIEYHG 422

  Fly   407 ------------ICQRSTS--EPDDTSDFNFLQGLSLKYEYEWPLNLLFSPTTIERYNNIFRFLL 457
                        :..|.||  ||..:.    ...|.|.|:.:|||::||:|..:|:||.:|::||
  Rat   423 KDHKADATQPREVPSRETSPREPPSSG----WAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLL 483

  Fly   458 IIRTYQYEIQRVWAKQTWRAKSAKDVPPNNKIITLRNYLMFFLNNMQYYIQVDVLESQFGILMNV 522
            .:|..|.|:|..||.|..| |..|....:.....|||::.|.::|:|||:|||||||||..|::.
  Rat   484 SVRRVQAELQHCWALQMQR-KHLKSNQTDAVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQ 547

  Fly   523 IKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGICEKFAHM-T 586
            |.|..|||.|:.||..||:|:|:..|:|              ..|::..|.::..:|..|..: :
  Rat   548 INSTRDFESIRLAHDHFLSNLLAQSFIL--------------LKPVFHCLNEILDLCHSFCSLVS 598

  Fly   587 QTKDPSDDL-EDEVDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLLLRLDFNCWFSASHNT 648
            |...|.|:. ..::..|.:.|..|.:.|.::|..|::......|:|||||||:|.:::.:..|
  Rat   599 QNLGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGT 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	89/375 (24%)
		GCP_C_terminal	349..642	CDD:461187	107/319 (34%)
Tubgcp4	NP_001386209.1	GCP_N_terminal	2..347	CDD:465456	89/375 (24%)
		GCP_C_terminal	350..655	CDD:461187	109/325 (34%)