DRSC/TRiP Functional Genomics Resources

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Protein Alignment Grip75 and Tubgcp6

DIOPT Version :9

Sequence 1:NP_609412.1 Gene:Grip75 / 34441 FlyBaseID:FBgn0026431 Length:650 Species:Drosophila melanogaster
Sequence 2:NP_001156791.1 Gene:Tubgcp6 / 328580 MGIID:2146071 Length:1769 Species:Mus musculus


Alignment Length:376 Identity:81/376 - (21%)
Similarity:152/376 - (40%) Gaps:47/376 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   297 ESEFFKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEIAVN----EVDLERQMGLIKDFFLLG 357
            :|...:..|.||...|:.|.....::..:..:||. :|:.||:    |:.||.....::.|.|:.
Mouse  1414 QSAVDESAVQLSELLTLPVLMKRSLMAPLAAHVSL-VSKAAVDYFFVELHLETHFEALRHFLLME 1477

  Fly   358 RGEF---YLEFCSQMVGTMETYRE---ERFKNVTRSFELAATVTGITDDLDKFSLICQR-----S 411
            .|||   ..:...:.:|..:|..|   ....|...|..|..::.|.|......|...:.     :
Mouse  1478 DGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHASNLSFALKYLPEVFA 1542

  Fly   412 TSEPDDTSDFNFLQGLSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTYQYEIQRVWAKQTWR 476
            .:.||      .|..|.|:|:.:||||::.:.:.:.:|:.||.|||.::...:.::.:    .:.
Mouse  1543 PNAPD------VLSCLELRYKVDWPLNIVITESCLNKYSGIFSFLLQLKLMMWTLKDI----CFH 1597

  Fly   477 AKSAKDVPPNNKIITLRNYLMFFLNNMQYYIQV----------DVLESQFGILMNVIKSRSDFEV 531
            .|....|......:..|. |..|.:.||::::|          .|...:|...:.|:   .|.|.
Mouse  1598 LKRTALVSHTAGSVQFRQ-LQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVV---GDLEE 1658

  Fly   532 IQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFG--ICEKFAHMTQTKDPSDD 594
            |||||..:|...:....|..::...:|:..|     |:..:||...  |.:.:...|..:.....
Mouse  1659 IQRAHAEYLHRAVFRGLLTEKAAPVMNIIHS-----IFSLVLKFRSQLISQNWGPATGPRGAEHP 1718

  Fly   595 LEDEVDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLLLRLDFNCWFSAS 645
            ....:.|...:|......|.:::..:.:......|...|||::||.::..|
Mouse  1719 NFPLMQQSYSTFKYYSHFLFKVVTKLVNRGYQPHLEDFLLRINFNNYYQDS 1769

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Grip75NP_609412.1 Spc97_Spc98 25..548 CDD:282045 63/275 (23%)
Tubgcp6NP_001156791.1 Spc97_Spc98 355..>611 CDD:282045
NBP1 <622..>752 CDD:285709
ARGLU 631..759 CDD:291991
Ehrlichia_rpt 672..1249 CDD:118064
DUF4200 689..785 CDD:290574
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 809..842
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 859..881
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1284..1360
Spc97_Spc98 <1403..1667 CDD:282045 62/267 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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