Protein Alignment Grip75 and t-Grip128

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_729045.1
• Gene: t-Grip128 / 317930
• FlyBaseID: FBgn0052232
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 818
• Identity: 151/818 - (18%)
• Similarity: 255/818 - (31%)
• Gaps: 317/818 - (38%)

  Fly     1 MIHDLLLACRSHNPEQLGIKAFNETTVI----DQFIH--------PCEREIFMDIIKIIKVYQEV 53
            ::..|.:|..|   .|:..|..|.|..:    ||.||        | .:::..|  :|.::..|:
  Fly   144 ILEALQMATES---SQVDPKDKNNTKCVADTEDQLIHKKSQKPKSP-RKKLTPD--QIQRLCDEI 202

  Fly    54 EQFTHSS-GRKSDTHGELP--------DSLHGYYL-LNLAKGIEMALEEYYAEIG-RLEKYCLGN 107
            ...|.|. |.......::|        .|.:.|.. |||.|   :|::|.:...| ::|.
  Fly   203 RDLTSSKYGSLHTVRSQIPMEQSKPLDTSDYNYSRELNLGK---VAVKENFTIKGAKMEL----- 259

  Fly   108 ERNSLSYVYNALYAKFPLLV-FMRN------------------LITEIHVLNLRGC-----VLLH 148
               .|:.|.|...|:.|.|| |.:|                  :..:.|:|....|     :|:.
  Fly   260 ---ELNVVQNKPSAEKPALVDFFKNESDMLYRIQTNWWQVDISVYNQAHILASNFCQGYADILIF 321

  Fly   149 NLHQQC--------EHGDIQLEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDA 205
            .|.:..        ||   ||...:.::       ||:| |:...|.:::| :.||
  Fly   322 QLWESQASIRKLSEEH---QLLSELIVL-------FFAS-ANCRSFKILND-NWEF--------- 365

  Fly   206 VDGSSFSKSATCSLLSAEKNP---------------EDYIWQYEV------NMSQLPGFFSIVLA 249
                ...:..||:|...::.|               .:.|..|.|      .:..|. |||:.|.
  Fly   366 ----RADEPLTCALKQLQEGPHLGEIIKSLKQMRHLRELIETYAVKGIRYDRLKTLT-FFSVALR 425

  Fly   250 EKVLFVGQTVLVFKMGRNVKVKNKTDP------LAAKLAELDSDD-IYQLWSGRESEFFKMVVDL 307
            :.:    :.|:.|.:....::.:..:|      :......|::.. :|:|...:..|...: ..|
  Fly   426 QLL----RPVIEFLVHFERRLTSGLEPATLQHFIETSRGHLETIKLLYELSQNKNQELHSL-RSL 485

  Fly   308 SNEDTINVFRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIKDFFLLGRGEFYLEFCSQ--MV 370
            ...||:.....:|....:...:||.|                     ||.....|.:|...  ..
  Fly   486 KTLDTLFTKSSQKTQPKLLRSLSASL---------------------LLHTVRAYCKFLDNWWST 529

  Fly   371 GTMETYREE-RFKNVTRSFELAATVTGITDDLDKFSL----------------ICQRSTSEPDD- 417
            |....|.|| .|:.:            :||:..::.|                |.||...|..|
  Fly   530 GDFADYHEEFPFEKI------------VTDERTEYVLRKSLMQTELQNSELFRIIQRHLLESSDG 582

  Fly   418 ---------TSDFNFLQGL------------------------SLKYEYEWP------------- 436
                     .|:|:.|.|:                        :::..:..|
  Fly   583 VAILYDSRTISEFHTLHGIEPEIRLHNSLIDAVIGEIAPYQIKAIEASHYVPDILQQLQSTDHDG 647

  Fly   437 LNLLFSPTTIE-----------RYNNIFRFLLIIRTY-------QYEIQRVWAKQTWRAKSAKDV 483
            :..||....:|           ..|.:.|..|....|       ..|.||:.
  Fly   648 IRRLFYSFHMETRPDPRKPAGHSINELLRNFLTCADYTPITEIISQEFQRLL------------- 699

  Fly   484 PPNNKIITLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSD----FEVIQRAHTVFLANVL 544
              |.:...:.:|:...|...|.|..|..|.|.| :|.|....||:    ||.::|.|.|...|.|
  Fly   700 --NRRTRLVNSYISGLLQEFQGYKVVRHLRSVF-LLWNYDHFRSEFEFFFEFLRRKHLVEATNKL 761

  Fly   545 SHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGICEKFAH--MTQTKDPSDDL------EDEVDQ 601
            .|..|..:.                 ||..:|.:|...||  ....:..:|.|      :.::|.
  Fly   762 KHIVLCQDF-----------------TLGHMFKVCVTEAHPEFICLRVRNDTLLNRIISQQQMDM 809

  Fly   602 LNESFGVQIASLIQLLVDVKSASCLGPLSQLLLRLDFN 639
            :|..|                        :|||.|:|:
  Fly   810 MNSCF------------------------RLLLNLNFS 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	81/420 (19%)
		GCP_C_terminal	349..642	CDD:461187	70/387 (18%)
t-Grip128	NP_729045.1	GCP5_NTD	10..121	CDD:454848