Protein Alignment Grip75 and Tubgcp3

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: XP_063131531.1
• Gene: Tubgcp3 / 306599
• RGDID: 1305726
• Length: 929
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 116/544 - (21%)
• Similarity: 206/544 - (37%)
• Gaps: 106/544 - (19%)

  Fly    47 IKVYQEVEQFTHSSGRKSDT-----HGELPD------SLHGYYLLNLAKGIEMALEEYYAEIGRL 100
            |:.|.:......|.|....:     |.||.:      .||....|...:|:.:.||...
  Rat   299 IRKYADQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNVGLESSL------ 357

  Fly   101 EKYCLGNERNSLSYVYNALYAKFPLLVFMRNLITEI-HVLNLRGCVLLHNLHQQCEHGDIQLEKA 164
                  ..|..|.:.|:.       .:.::.|...: |....:|..|...:|...:.||..::..
  Rat   358 ------TLRRLLVWTYDP-------KIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSL 409

  Fly   165 IKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSKSATCSLLSAEKNPEDY 229
            ::.|:..|.:...|.|..|:..|.::|.:.|||:...||...                     |.
  Rat   410 VQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKT---------------------DR 453

  Fly   230 IW--QYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVKVKNKTDPLAAKLAELDSDDIYQL 292
            :|  :|.:..|.:|.|.::..:.|||.:|:::....     :|.:...|....:|...|.:
  Rat   454 LWHDKYTLRKSMIPSFITMDQSRKVLLIGKSINFLH-----QVCHDQTPTTKMIAVTKSAE---- 509

  Fly   293 WSGRESEFFKMVVDLSN--EDTINV--FRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIKDF 353
             |.|::.  .:..||.|  :..|:.  |...|.::|:.|           .:..|...|..::.:
  Rat   510 -SPRDAA--DLFTDLENAFQGKIDAAYFETSKYLLDVLN-----------RKYSLLEHMQAMRRY 560

  Fly   354 FLLGRGEFYLEFCSQMVGTMETYREERFK--------NVTRSFELAATVTGITDDLDKF--SLIC 408
            .|||:|:|....       |:..:.|..:        |:|...|.|...|....|..:.  .|..
  Rat   561 LLLGQGDFIRHL-------MDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDV 618

  Fly   409 QRSTSEPDDTSDFNFLQGLSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTYQYEIQRVWAKQ 473
            :.....|.||....|    ||.|..:.|:..:|:...:..|..:|.||...:..:|.:..:....
  Rat   619 RLLEVSPGDTGWDVF----SLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGH 679

  Fly   474 TWRAKSAKDVPPNNKII----TLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVIQR 534
            ...||..:::|..:.::    .|.:.::.|::.|||||..:|||..:..|.|.::...|.:.|..
  Rat   680 MCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIA 744

  Fly   535 AHTVFLANVLSHCFLLNESETQLN 558
            ||..||..:.|.|.|.:.|...||
  Rat   745 AHEAFLDTITSRCLLDSNSRVLLN 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	59/310 (19%)
		GCP_C_terminal	349..642	CDD:461187	55/224 (25%)
Tubgcp3	XP_063131531.1	None