Protein Alignment Grip75 and Tubgcp3

DIOPT Version :10

• Sequence 1: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_932148.1
• Gene: Tubgcp3 / 259279
• MGIID: 2183752
• Length: 905
• Species: Mus musculus
• Alignment Length: 657
• Identity: 137/657 - (20%)
• Similarity: 241/657 - (36%)
• Gaps: 139/657 - (21%)

  Fly    58 HSSGRKSDTHGELPDSLHGYYLLNLAKGIEMALEEYYAEIGRLEKYC---------LGNE----- 108
            |:..||......| |...|....:....:...|:|||..:..|....         ||.|
Mouse   299 HNKIRKYADQRSL-DRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQLEDDQGVNLGLESSLTL 362

  Fly   109 RNSLSYVYNALYAKFPLLVFMRNLITEI-HVLNLRGCVLLHNLHQQCEHGDIQLEKAIKIIMKPV 172
            |..|.:.|:.       .:.::.|...: |....:|..|...:|...:.||..::..::.|:..|
Mouse   363 RRLLVWTYDP-------KIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSLVQHILSLV 420

  Fly   173 KNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSKSATCSLLSAEKNPEDYIW--QYEV 235
            .:...|.|..|:..|.::|.:.|||:...||...                     |.:|  :|.:
Mouse   421 SHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKT---------------------DRLWHDKYTL 464

  Fly   236 NMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVKVKNKTDPLAAKLAELDSDDIYQLWSGRESEF 300
            ..|.:|.|.::..:.|||.:|:::....     :|.:...|....:|...|.:     |.|::.
Mouse   465 RKSMIPSFITMDQSRKVLLIGKSINFLH-----QVCHDQTPTTKMIAVTKSAE-----SPRDAA- 518

  Fly   301 FKMVVDLSN--EDTINV--FRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIKDFFLLGRGEF 361
             .:..||.|  :..|:.  |...|.::|:.|           .:..|...|..::.:.|||:|:|
Mouse   519 -DLFTDLENAFQGKIDAAYFETSKYLLDVLN-----------KKYSLLEHMQAMRRYLLLGQGDF 571

  Fly   362 YLEFCSQMVGTMETYREERFK--------NVTRSFELAATVTGITDDLDKF--SLICQRSTSEPD 416
            ....       |:..:.|..:        |:|...|.|...|....|..:.  .|..:.....|.
Mouse   572 IRHL-------MDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILKRLDVRLLEVSPG 629

  Fly   417 DTSDFNFLQGLSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTYQYEIQRVWAKQTWRAKSAK 481
            ||....|    ||.|..:.|:..:|:...:..|..:|.||...:..:|.:..:.......||..:
Mouse   630 DTGWDVF----SLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLR 690

  Fly   482 DVPPNNKII----TLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVIQRAHTVFLAN 542
            ::|..:.::    .|.:.::.|::.|||||..:|||..:..|.|.::...|.:.|..||..||..
Mouse   691 NMPEFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLNT 755

  Fly   543 VLSHCFLLNESETQLN--------VTGSQN-RNPIYGTLLKLFGICEKFAHMTQTKDPSDDLEDE 598
            :.|.|.|.:.|...||        :...|| ::.:|...|      |:.....|.::.....|.|
Mouse   756 ITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDVMYRAAL------EELQRRLQFEEKKKQREIE 814

  Fly   599 ----------------VDQLNESFGVQIASL----------IQLLVDVKSASCLGPLSQLLLRLD 637
                            :.:..:|.....:.|          :|..:.:.:.|....|..|..|||
Mouse   815 GQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQGVVQQFLVLLTTSSDESLQFLSFRLD 879

  Fly   638 FNCWFSA 644
            ||..:.|
Mouse   880 FNEHYKA 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	60/302 (20%)
		GCP_C_terminal	349..642	CDD:461187	74/341 (22%)
Tubgcp3	NP_932148.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..193
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..239
		GCP_N_terminal	249..550	CDD:465456	60/302 (20%)
		GCP_C_terminal	553..884	CDD:461187	76/347 (22%)